Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Oncology
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101 Real-world outcomes with recombinant factor VIIa treatment of acute bleeds in haemophilia patients with inhibitors: results from the international ONE registry Haemophilia, April 18, 2013 Review Article Clinical Article
102 A chemically-modified inactive antithrombin as a potent antagonist of fondaparinux and heparins anticoagulant activity Journal of Thrombosis and Haemostasis, April 17, 2013 Clinical Article
103 Effect of splenectomy on iron balance in patients with β- Thalassaemia Major: a long term follow up European Journal of Haematology, April 16, 2013 Clinical Article
104 40K glycoPEGylated, recombinant FVIIa: 3-month, double-blind, randomized trial of safety, pharmacokinetics, and preliminary efficacy in hemophilia patients with inhibitors Journal of Thrombosis and Haemostasis, April 15, 2013 Clinical Article
105 The predictive ability of bleeding risk stratification models in very old patients on VKA treatment for venous thromboembolism Results of the Prospective Collaborative EPICA study Journal of Thrombosis and Haemostasis, April 15, 2013 Clinical Article
106 Maternal cerebral venous thrombosis, uncommon but serious disorder, pathologic predictors and contribution of prothrombotic abnormalities Blood Coagulation & Fibrinolysis, April 15, 2013 Clinical Article
107 Malignant epithelioid hemangioendothelioma progressing after chemotherapy and Interferon treatment: A case presentation and a brief review of the literature Journal of Cancer Research and Therapeutics, April 15, 2013
108 Patient-reported outcomes of 182 adults with severe haemophilia in Germany comparing prophylactic vs. on-demand replacement therapy Haemophilia, April 12, 2013 Clinical Article
109 Physical activity and functional abilities in adult males with haemophilia: a cross-sectional survey from a single US haemophilia treatment centre Haemophilia, April 12, 2013 Clinical Article
110 Statin Therapy and Levels of Hemostatic Factors in a Healthy Population: the Multi-Ethnic Study of Atherosclerosis Journal of Thrombosis and Haemostasis, April 11, 2013 Clinical Article
111 A randomised controlled trial of fresh frozen plasma for treating venom induced consumption coagulopathy in Australian snakebite (ASP-18) Journal of Thrombosis and Haemostasis, April 11, 2013 Clinical Article
112 Increased promyelocytic-derived microparticles: a novel potential factor for coagulopathy in acute promyelocytic leukemia Annals of Hematology, April 11, 2013 Clinical Article
113 Successful percutaneous coronary intervention in a patient with combined deficiency of FV and FVIII due to novel compound heterozygous mutations in LMAN1 Haemophilia, April 11, 2013 Clinical Article
114 Diagnostic possibilities of specific fibrin(ogen) degradation products in relation to venous thromboembolism Blood Coagulation & Fibrinolysis, April 11, 2013 Clinical Article
115 ADAMTS13 unbound to larger von Willebrand factor multimers in cryosupernatant: implications for selection of plasma preparations for thrombotic thrombocytopenic purpura treatment Transfusion, April 10, 2013 Clinical Article
116 Molecular basis of quantitative fibrinogen disorders in 27 patients from India Haemophilia, April 10, 2013 Clinical Article
117 Tranexamic acid without prophylactic factor replacement for prevention of bleeding in hereditary bleeding disorder patients undergoing endoscopy: a pilot study Haemophilia, April 10, 2013 Clinical Article
118 Prevalence and associations for abnormal bleeding times in patients with renal insufficiency Platelets, April 10, 2013 Clinical Article
119 The association between the 4G/5G polymorphism in the promoter of the plasminogen activator inhibitor-1 gene and extension of postsurgical calf vein thrombosis Blood Coagulation & Fibrinolysis, April 10, 2013 Clinical Article
120 Anticoagulation for prevention and treatment of cancer-related venous thromboembolism British Journal of Haematology, April 9, 2013 Clinical Article
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summary1 Management and outcomes for patients with TTP: Analysis of 100 cases at a single institution American Journal of Hematology, April 29, 2013
2 Anticoagulation for prevention and treatment of cancer-related venous thromboembolism British Journal of Haematology, April 9, 2013
3
Adherence to anticoagulant treatment with dabigatran in a real-world setting
Journal of Thrombosis and Haemostasis, April 19, 2013
Exclusive Author Commentary
4 Impact of a venous thromboembolism (VTE) prophylaxis smart order set: Improved compliance, fewer events American Journal of Hematology, April 8, 2013
5 Bleeding risk in warfarinized patients with a therapeutic INR: the effect of low factor IX levels Journal of Thrombosis and Haemostasis, April 18, 2013
6 Intracranial haemorrhage in von Willebrand disease: a report on six cases Haemophilia, April 23, 2013
7 Advances in megakaryocytopoiesis and thrombopoiesis: from bench to bedside British Journal of Haematology, April 25, 2013 Review Article
8 ADAMTS13 unbound to larger von Willebrand factor multimers in cryosupernatant: implications for selection of plasma preparations for thrombotic thrombocytopenic purpura treatment Transfusion, April 10, 2013
9 Venous thromboembolism in adults treated for acute lymphoblastic leukaemia: Effect of fresh frozen plasma supplementation Thrombosis and Haemostasis, April 23, 2013
10 The predictive ability of bleeding risk stratification models in very old patients on VKA treatment for venous thromboembolism Results of the Prospective Collaborative EPICA study Journal of Thrombosis and Haemostasis, April 15, 2013
11 FcRIIa proteolysis as a diagnostic biomarker for heparin-induced thrombocytopenia Journal of Thrombosis and Haemostasis, April 3, 2013
12 Unresponsive thrombotic thrombocytopenic purpura in critically ill adults Intensive Care Medicine, April 5, 2013
13 Statin Therapy and Levels of Hemostatic Factors in a Healthy Population: the Multi-Ethnic Study of Atherosclerosis Journal of Thrombosis and Haemostasis, April 11, 2013
14 Post-thrombotic syndrome: a clinical review Journal of Thrombosis and Haemostasis, March 8, 2013 Review Article
15 Product-dependent anti-factor VIII antibodies Haemophilia, April 25, 2013
16 Anticoagulant use in patients with cancer associated venous thromboembolism: A retrospective cohort study Thrombosis Research, March 22, 2013 Evidence Based Medicine
17 Plasma concentration of protein Z and protein Z-dependent protease inhibitor in patients with haemophilia A Thrombosis Research, April 2, 2013 Evidence Based Medicine
18 Whole blood clots are more resistant to lysis than plasma clots - greater efficacy of rivaroxaban Thrombosis Research, April 2, 2013
19 Platelet size for distinguishing between inherited thrombocytopenias and immune thrombocytopenia: a multicentric, real life study British Journal of Haematology, April 26, 2013 Review Article
20 Successful percutaneous coronary intervention in a patient with combined deficiency of FV and FVIII due to novel compound heterozygous mutations in LMAN1 Haemophilia, April 11, 2013
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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