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Oncology - Coagulation/Bleeding Dz News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (1) Full Text Articles (120) Focus on Lung
Ranked, sorted, and summarized by MDLinx editors from the latest literature
Topics:

981 Use of recombinant factor VIIa for the prevention and treatment of bleeding in patients without hemophilia: a systematic review and meta-analysis Full Text Canadian Medical Association Journal, January 12, 2011    Evidence Based Medicine

982 Fondaparinux cross-reacts with heparin antibodies in vitro in a patient with fondaparinux-related thrombocytopenia Blood Coagulation & Fibrinolysis, January 10, 2011

983 Perioperative bridging therapy with low molecular weight heparin for patients with inherited thrombophilia and antiphospholipid syndrome on long-term acenokumarol therapy Blood Coagulation & Fibrinolysis, January 10, 2011

984 Treatment of adverse perinatal outcome in inherited thrombophilias: a clinical study Blood Coagulation & Fibrinolysis, January 10, 2011

985 Reviewed diagnosis of primary and secondary immune thrombocytopenic purpura in 79 adult patients hospitalized in 2000–2002 Blood Coagulation & Fibrinolysis, January 10, 2011

986 Physical activity and joint function in adults with severe haemophilia on long-term prophylaxis Blood Coagulation & Fibrinolysis, January 10, 2011

987 A comparison of the mechanical, kinetic, and biochemical properties of fibrin clots formed with two different fibrin sealants Blood Coagulation & Fibrinolysis, January 10, 2011

988 Carbon monoxide releasing molecule-2 enhances coagulation and attenuates fibrinolysis by two mechanisms: insights gained with colloid dilution Blood Coagulation & Fibrinolysis, January 10, 2011

989 Carbon monoxide releasing molecule-2 attenuates the anticoagulant and amplifies the hypofibrinolytic effects of hypothermia in human plasma in vitro Blood Coagulation & Fibrinolysis, January 10, 2011

990 Partitagin, a unique beta, gamma-fibrinogenase that inhibits platelet aggregation from Hippasa partita spider venom Blood Coagulation & Fibrinolysis, January 10, 2011

991 Polymorphism of clotting factors in Hungarian patients with Raynaud's phenomenon Blood Coagulation & Fibrinolysis, January 10, 2011

992 ADAMTS-13 Antigen and Activity Levels in Thrombocytopenic Disorders Including Thrombotic Thrombocytopenic Purpura in Kuwait Acta Haematologica, January 10, 2011

993 A patient with 'spontaneous' heparin-induced thrombocytopenia and thrombosis after undergoing knee replacement Blood Coagulation & Fibrinolysis, January 10, 2011

994 In Vitro Effects of Detergent Sclerosants on Clot Formation and Fibrinolysis European Journal of Vascular and Endovascular Surgery, January 7, 2011

995 Challenges of multiple mutations in individual patients with haemophilia European Journal of Haematology, January 7, 2011

996 Etiology and Assessment of Hypercoagulability with Lessons from Heparin-Induced Thrombocytopenia Full Text Anesthesia & Analgesia, January 7, 2011

997 Venous thromboembolism following microsurgical breast reconstruction: an objective analysis in 225 consecutive patients using low-molecular-weight heparin prophylaxis Plastic and Reconstructive Surgery, January 7, 2011

998 Inflammation and thrombosis in essential thrombocythemia and polycythemia vera: different role of C-reactive protein and Pentraxin 3 Haematologica, January 6, 2011

999 Clinical and genetic aspects Bernard-Soulier syndrome: searching for genotype/phenotype correlations Haematologica, January 6, 2011

1000 Very long-term remission induced by short-term rituximab monotherapy in a patient with heavily pretreated, chronic immune thrombocytopenic purpura European Journal of Haematology, January 5, 2011    Clinical Article

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Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

Read the article summary

HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 Management and outcomes for patients with TTP: Analysis of 100 cases at a single institution American Journal of Hematology, April 29, 2013

2 Anticoagulation for prevention and treatment of cancer-related venous thromboembolism British Journal of Haematology, April 9, 2013

3 Adherence to anticoagulant treatment with dabigatran in a real-world setting Journal of Thrombosis and Haemostasis, April 19, 2013
Exclusive Author Commentary

4 Impact of a venous thromboembolism (VTE) prophylaxis smart order set: Improved compliance, fewer events American Journal of Hematology, April 8, 2013

5 Bleeding risk in warfarinized patients with a therapeutic INR: the effect of low factor IX levels Journal of Thrombosis and Haemostasis, April 18, 2013

6 Intracranial haemorrhage in von Willebrand disease: a report on six cases Haemophilia, April 23, 2013

7 Advances in megakaryocytopoiesis and thrombopoiesis: from bench to bedside British Journal of Haematology, April 25, 2013    Review Article

8 ADAMTS13 unbound to larger von Willebrand factor multimers in cryosupernatant: implications for selection of plasma preparations for thrombotic thrombocytopenic purpura treatment Transfusion, April 10, 2013

9 Venous thromboembolism in adults treated for acute lymphoblastic leukaemia: Effect of fresh frozen plasma supplementation Thrombosis and Haemostasis, April 23, 2013

10 The predictive ability of bleeding risk stratification models in very old patients on VKA treatment for venous thromboembolism Results of the Prospective Collaborative EPICA study Journal of Thrombosis and Haemostasis, April 15, 2013

11 FcRIIa proteolysis as a diagnostic biomarker for heparin-induced thrombocytopenia Journal of Thrombosis and Haemostasis, April 3, 2013

12 Unresponsive thrombotic thrombocytopenic purpura in critically ill adults Intensive Care Medicine, April 5, 2013

13 Statin Therapy and Levels of Hemostatic Factors in a Healthy Population: the Multi-Ethnic Study of Atherosclerosis Journal of Thrombosis and Haemostasis, April 11, 2013

14 Post-thrombotic syndrome: a clinical review Journal of Thrombosis and Haemostasis, March 8, 2013    Review Article

15 Product-dependent anti-factor VIII antibodies Haemophilia, April 25, 2013

16 Anticoagulant use in patients with cancer associated venous thromboembolism: A retrospective cohort study Thrombosis Research, March 22, 2013    Evidence Based Medicine

17 Plasma concentration of protein Z and protein Z-dependent protease inhibitor in patients with haemophilia A Thrombosis Research, April 2, 2013    Evidence Based Medicine

18 Whole blood clots are more resistant to lysis than plasma clots - greater efficacy of rivaroxaban Thrombosis Research, April 2, 2013

19 Platelet size for distinguishing between inherited thrombocytopenias and immune thrombocytopenia: a multicentric, real life study British Journal of Haematology, April 26, 2013    Review Article

20 Successful percutaneous coronary intervention in a patient with combined deficiency of FV and FVIII due to novel compound heterozygous mutations in LMAN1 Haemophilia, April 11, 2013

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncologymore

Other Topics in Oncology

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