Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Oncology
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D Scott Cunningham MD, PhD
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341 In vitro characterization of recombinant factor VIII concentrates reveals significant differences in protein content, activity and thrombin activation profile Haemophilia, January 4, 2013 Review Article
342 A pilot study to assess the hemostatic function of pathogen-reduced platelets in patients with thrombocytopenia Transfusion, January 3, 2013 Clinical Article
343 Repeated short-term use of eltrombopag in patients with chronic immune thrombocytopenia (ITP) British Journal of Haematology, January 3, 2013 Clinical Article
344 Derivation and Validation of a Scoring System to Identify Patients with Bacteremia and Hematological Malignancies at Higher Risk for Mortality PLOS ONE, January 2, 2013
345 Pain in thalassaemia: the effects of age on pain frequency and severity British Journal of Haematology, January 2, 2013 Review Article
346
Lack of Prognostic Effect of Carbonic Anhydrase-9, Hypoxia Inducible Factor-1alpha and Bcl-2 in 286 Patients with Early Squamous Cell Carcinoma of the Glottic Larynx Treated with Radiotherapy
Clinical Oncology, December 31, 2012
Exclusive Author Commentary
347 The effect of a preoperative erythropoietin protocol as part of a multifaceted blood management program in daily clinical practice Transfusion, December 28, 2012
348 Avoiding room temperature storage and delayed cryopreservation provide better postthaw potency in hematopoietic progenitor cell grafts Transfusion, December 28, 2012
349 Does anemia impact hospital readmissions after coronary artery bypass surgery? Transfusion, December 28, 2012
350 Blood supply safety in Afghanistan: a national assessment of high-volume facilities Transfusion, December 26, 2012
351 Hydroxyurea responsiveness in β-thalassemic patients is determined by the stress response adaptation of erythroid progenitors and their differentiation propensity Full Text Haematologica, December 21, 2012
352 CD72 gene expression in immune thrombocytopenia Platelets, December 21, 2012
353 Effects of FEIBA on platelet and leucocyte activation in severe haemophilia patients with inhibitors Platelets, December 21, 2012
354 Comparison of biventricular dimensions and function between pediatric sickle-cell disease and thalassemia major patients without cardiac iron American Journal of Hematology, December 21, 2012
355 Successful Management of a Possible Antibiotic-Related Acquired Factor V Inhibitor: A Case Report and Review of the Literature Acta Haematologica, December 21, 2012
356 Differential effects of the type of iron chelator on the absolute number of hematopoietic peripheral progenitors in patients with β-thalassemia major Full Text Haematologica, December 20, 2012
357 Splenectomy as a curative treatment for immune thrombocytopenia: a retrospective analysis of 233 patients with a minimum follow-up of 10years Full Text Haematologica, December 20, 2012
358 Correlation between platelet phenotype and NBEAL2 genotype in patients with congenital thrombocytopenia and α-granule deficiency Full Text Haematologica, December 20, 2012
359 Hydrogen sulfide–releasing aspirin derivative acs14 exerts strong antithrombotic effects in vitro and in vivo Arteriosclerosis, Thrombosis, and Vascular Biology, December 20, 2012
360 Prevalence of clinical hip abnormalities in haemophilia A and B: an analysis of the UDC database Haemophilia, December 19, 2012
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summary1 Management and outcomes for patients with TTP: Analysis of 100 cases at a single institution American Journal of Hematology, April 29, 2013
2 Anticoagulation for prevention and treatment of cancer-related venous thromboembolism British Journal of Haematology, April 9, 2013
3
Adherence to anticoagulant treatment with dabigatran in a real-world setting
Journal of Thrombosis and Haemostasis, April 19, 2013
Exclusive Author Commentary
4 Impact of a venous thromboembolism (VTE) prophylaxis smart order set: Improved compliance, fewer events American Journal of Hematology, April 8, 2013
5 Bleeding risk in warfarinized patients with a therapeutic INR: the effect of low factor IX levels Journal of Thrombosis and Haemostasis, April 18, 2013
6 Intracranial haemorrhage in von Willebrand disease: a report on six cases Haemophilia, April 23, 2013
7 Advances in megakaryocytopoiesis and thrombopoiesis: from bench to bedside British Journal of Haematology, April 25, 2013 Review Article
8 ADAMTS13 unbound to larger von Willebrand factor multimers in cryosupernatant: implications for selection of plasma preparations for thrombotic thrombocytopenic purpura treatment Transfusion, April 10, 2013
9 Venous thromboembolism in adults treated for acute lymphoblastic leukaemia: Effect of fresh frozen plasma supplementation Thrombosis and Haemostasis, April 23, 2013
10 The predictive ability of bleeding risk stratification models in very old patients on VKA treatment for venous thromboembolism Results of the Prospective Collaborative EPICA study Journal of Thrombosis and Haemostasis, April 15, 2013
11 FcRIIa proteolysis as a diagnostic biomarker for heparin-induced thrombocytopenia Journal of Thrombosis and Haemostasis, April 3, 2013
12 Unresponsive thrombotic thrombocytopenic purpura in critically ill adults Intensive Care Medicine, April 5, 2013
13 Statin Therapy and Levels of Hemostatic Factors in a Healthy Population: the Multi-Ethnic Study of Atherosclerosis Journal of Thrombosis and Haemostasis, April 11, 2013
14 Post-thrombotic syndrome: a clinical review Journal of Thrombosis and Haemostasis, March 8, 2013 Review Article
15 Product-dependent anti-factor VIII antibodies Haemophilia, April 25, 2013
16 Anticoagulant use in patients with cancer associated venous thromboembolism: A retrospective cohort study Thrombosis Research, March 22, 2013 Evidence Based Medicine
17 Plasma concentration of protein Z and protein Z-dependent protease inhibitor in patients with haemophilia A Thrombosis Research, April 2, 2013 Evidence Based Medicine
18 Whole blood clots are more resistant to lysis than plasma clots - greater efficacy of rivaroxaban Thrombosis Research, April 2, 2013
19 Platelet size for distinguishing between inherited thrombocytopenias and immune thrombocytopenia: a multicentric, real life study British Journal of Haematology, April 26, 2013 Review Article
20 Successful percutaneous coronary intervention in a patient with combined deficiency of FV and FVIII due to novel compound heterozygous mutations in LMAN1 Haemophilia, April 11, 2013
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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