Oncology - Coagulation/Bleeding Dz News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (3) Full Text Articles (120) Focus on Hematology

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

201 Whole blood clots are more resistant to lysis than plasma clots - greater efficacy of rivaroxaban Thrombosis Research, April 2, 2013 Clinical Article

202 Plasma concentration of protein Z and protein Z-dependent protease inhibitor in patients with haemophilia A Thrombosis Research, April 2, 2013 Evidence Based Medicine

203 Low ADAMTS-13 activity during hemorrhagic events with disseminated intravascular coagulation International Journal of Hematology, April 2, 2013 Clinical Article

204 Reduced prevalence of arterial thrombosis in von Willebrand disease Journal of Thrombosis and Haemostasis, March 29, 2013 Clinical Article

205 Ankle fusion in patients with haemophilia Haemophilia, March 29, 2013 Clinical Article

206 Effect of low-dose supplements of menaquinone-7 [vitamin K2(35)] on the stability of oral anticoagulant treatment: dose-response relationship in healthy volunteers Journal of Thrombosis and Haemostasis, March 28, 2013 Clinical Article

207 Randomized, Controlled, Parallel-Group Trial of Routine Prophylaxis Versus On-Demand Treatment With rFVIII-FS in Adults With Severe Hemophilia A (SPINART) Journal of Thrombosis and Haemostasis, March 28, 2013 Clinical Article

208 Adjudication of bleeding outcomes in an international thromboprophylaxis trial in critical illness Thrombosis Research, March 27, 2013 Evidence Based Medicine Clinical Article

209 Aptamer BAX 499 Mediates Inhibition of Tissue Factor Pathway Inhibitor Via Interaction with Multiple Domains of the Protein Journal of Thrombosis and Haemostasis, March 27, 2013 Clinical Article

210 Differentiating disseminated intravascular coagulation (DIC) with the fibrinolytic phenotype from coagulopathy of trauma and acute coagulopathy of trauma-shock (COT/ACOTS) Journal of Thrombosis and Haemostasis, March 27, 2013 Clinical Article

211 Activated prothrombin complex concentrate (APCC)-mediated activation of factor (F)VIII in mixtures of FVIII and APCC enhances hemostatic effectiveness Journal of Thrombosis and Haemostasis, March 27, 2013 Clinical Article

212 Influence of CYP2C19*2 and *3 loss-of-function alleles on pharmacodynamic effects of standard- and high-dose clopidogrel in East Asians undergoing percutaneous coronary intervention: the results of the ACCEL-DOUBLE-2N3 study Journal of Thrombosis and Haemostasis, March 26, 2013 Clinical Article

213 Cardiac catheterization and intervention in haemophilia patients: prospective evaluation of the 2009 institutional guideline Haemophilia, March 26, 2013 Clinical Guideline Clinical Article

214 Fibrocytes mediate intimal hyperplasia post-vascular injury and are regulated by two tissue factor-dependent mechanisms Journal of Thrombosis and Haemostasis, March 25, 2013 Clinical Article

215 Genotyping and phenotyping of platelet function disorders Journal of Thrombosis and Haemostasis, March 25, 2013 Clinical Article

216 Monitoring rFVIII prophylaxis dosing using global haemostasis assays Haemophilia, March 25, 2013 Clinical Article

217 Predicting Response to rFVIIa in Neonates With Intractable Bleeding or Severe Coagulation Disturbances Journal of Pediatric Hematology/Oncology, March 25, 2013 Clinical Article

218 Blood hypomethylation of inflammatory genes mediates the effects of metal-rich airborne pollutants on blood coagulation Occupational and Environmental Medicine, March 22, 2013 Review Article

219 Protected by nature Effects of strenuous physical exercise on FVIII activity in moderate and mild haemophilia A patients: a pilot study Haemophilia, March 22, 2013 Clinical Article

220 Immune tolerance induction in haemophilia A patients with inhibitors by treatment with recombinant factor VIII: a retrospective non-interventional study Haemophilia, March 22, 2013 Clinical Article

50 available pages First Previous 11 12 13 14 15 16 17 18 19 20 Next Last

Clinical Pearls in Oncology

The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 Antiplatelet drugs for polycythaemia vera and essential thrombocythaemia Cochrane Reviews, May 10, 2013 Evidence Based Medicine

2 Management and outcomes for patients with TTP: Analysis of 100 cases at a single institution American Journal of Hematology, April 29, 2013

3 Use of New Oral Anticoagulants in Antiphospholipid Syndrome Current Rheumatology Reports, May 7, 2013

4 Prophylaxis of catheter-related deep vein thrombosis in cancer patients with low-dose warfarin, low molecular weight heparin, or control: a randomized, controlled, phase III study Cancer Chemotherapy and Pharmacology, May 6, 2013

5 The role of Epstein-Barr virus (EBV) and cytomegalovirus (CMV) in immune thrombocytopenia Hematology, May 24, 2013

6 Anticoagulation for prevention and treatment of cancer-related venous thromboembolism British Journal of Haematology, April 9, 2013

7 Non-transfusional approach to increase platelet count in patients with cirrhosis and thrombocytopenia Hepatology, May 29, 2013 Review Article

8 Advances in the treatment of inherited coagulation disorders Haemophilia, May 1, 2013

9 Periprocedural antiplatelet therapy: recommendations for standardized reporting in patients on antiplatelet therapy Journal of Thrombosis and Haemostasis, May 13, 2013

10 Safety and efficacy of splenectomy in over-65 year old patients with immune thrombocytopenia European Journal of Haematology, May 22, 2013

11 Pacemaker or Defibrillator Surgery without Interruption of Anticoagulation New England Journal of Medicine, May 20, 2013 Evidence Based Medicine

12 The New Oral Anticoagulants in Clinical Practice Mayo Clinic Proceedings, May 13, 2013

13 Alloantibodies in previously untreated hemophilia A patients: the role of environmental factors Hematology, May 24, 2013

14 Screening for occult malignancy with FDG-PET/CT in patients with unprovoked venous thromboembolism International Journal of Cancer, April 30, 2013

15 D-Dimer Elevation and Paresis Predict Thromboembolic Events During Bevacizumab Therapy for Recurrent Malignant Glioma Anticancer Research, May 8, 2013

16 Desmopressin acetate (DDAVP) for preventing and treating acute bleeds during pregnancy in women with congenital bleeding disorders Cochrane Reviews, May 10, 2013 Evidence Based Medicine

17 Inhibitors in haemophilia B: the Italian experience Haemophilia, May 6, 2013

18 Normal cleavage of von Willebrand factor by ADAMTS13 in the absence of factor VIII in patients with severe hemophilia A Journal of Thrombosis and Haemostasis, May 21, 2013

19 Acquired von Willebrand syndrome in a patient with monoclonal gammopathy of undetermined significance Blood Coagulation & Fibrinolysis, May 14, 2013

20 Towards standardization of the clot waveform analysis and recommendations for its clinical applications Journal of Thrombosis and Haemostasis, May 13, 2013

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more

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Oncology - Coagulation/Bleeding Dz News & Articles

Articles

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

HCC risk increased in patients with AIDS

RAB25 is a prognostic marker for ovarian cancer

Most Popular Oncology Articles

Other Topics in Oncology