GI Oncology News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (9) Full Text Articles (274) Focus on Pediatric

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

101 Cullin 4B is a novel prognostic marker that correlates with colon cancer progression and pathogenesis Medical Oncology, May 10, 2013 Clinical Article

102 Unusually Early Presentation of Small-Bowel Adenocarcinoma in a Patient With Peutz-Jeghers Syndrome Journal of Pediatric Hematology/Oncology, May 10, 2013

103 Expression and prognostic role of c-Myb as a novel cell cycle protein in esophageal squamous cell carcinoma Clinical and Translational Oncology, May 10, 2013 Clinical Article

104 Myeloid Differentiation Factor 88 Promotes Growth and Metastasis of Human Hepatocellular Carcinoma Clinical Cancer Research, May 10, 2013 Clinical Article

105 Two-week Schedule of Hypofractionated Radiotherapy as a Local Salvage Treatment for Small Hepatocellular Carcinoma Journal of Gastroenterology and Hepatology, May 10, 2013 Clinical Article

106 What studies are appropriate and necessary for staging gastric adenocarcinoma- Results of an international RAND/UCLA expert panel Gastric Cancer, May 10, 2013 Review Article
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107 Gastrointestinal Lymphoma: Recent Advances in Diagnosis and Treatment Digestion, May 10, 2013 Review Article

108 A Direct Comparison of the Prevalence of Advanced Adenoma and Cancer between Surveillance and Screening Colonoscopies Digestion, May 10, 2013 Review Article

109 Association between tuberculosis infections and non-pulmonary malignancies: a nationwide population-based study British Journal of Cancer, May 9, 2013

110 Underwater EMR of sporadic laterally spreading nonampullary duodenal adenomas Gastrointestinal Endoscopy, May 9, 2013 Clinical Article

111 Palliative brachytherapy with or without primary stent placement in patients with oesophageal cancer, a randomised phase III trial Radiotherapy & Oncology, May 9, 2013 Clinical Article

112 Transarterial Chemoembolization Using DEBIRI for Treatment of Hepatic Metastases from Colorectal Cancer Anticancer Research, May 9, 2013 Clinical Article

113 Normalization of Serum p53 Antibody Levels in Patients after Curative Resection for Colorectal Cancer Anticancer Research, May 9, 2013 Clinical Article

114 BRAF V600E mutation detection by immunohistochemistry in colorectal carcinoma Genes, Chromosomes and Cancer, May 9, 2013 Clinical Article

115 Downregulated expression of hepatoma-derived growth factor (HDGF) reduces gallbladder cancer cell proliferation and invasion Medical Oncology, May 9, 2013 Clinical Article

116 Integrated Metabolite and Gene Expression Profiles Identify Lipid Biomarkers Associated With Progression of Hepatocellular Carcinoma and Patient Outcomes Gastroenterology, May 9, 2013 Clinical Article

117 Risk of endocrine pancreatic insufficiency in patients receiving adjuvant chemoradiation for resected gastric cancer Radiotherapy & Oncology, May 9, 2013 Clinical Article

118 Extended Lymphadenectomy in Gastric Cancer Is Debatable World Journal of Surgery, May 9, 2013 Clinical Article

119 Identification of Novel Variants in Colorectal Cancer Families by High-Throughput Exome Sequencing Cancer Epidemiology, Biomarkers & Prevention, May 8, 2013 Clinical Article

120 Macrophages stimulate gastric and colorectal cancer invasion through EGFR Y1086, c-Src, Erk1/2 and Akt phosphorylation and smallGTPase activity Oncogene, May 8, 2013 Clinical Article

50 available pages First Previous 6 7 8 9 10 11 12 13 14 15 Next Last

Clinical Pearls in Oncology

The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 Safety and efficacy of calcium and magnesium infusions in the chemoprevention of oxaliplatin induced sensory neuropathy in digestive tract cancers: A meta-analysis Journal of Digestive Diseases, March 18, 2013

2 Long-term outcome of palliative therapy for gastric outlet obstruction caused by unresectable gastric cancer in patients with good performance status: endoscopic stenting versus surgery Gastrointestinal Endoscopy, April 8, 2013

3 Assessment of HER2 gene amplification in adenocarcinomas of the stomach or gastroesophageal junction in the INT-0116/SWOG9008 clinical trial Annals of Oncology, April 4, 2013

4 Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2×2 factorial trial The Lancet Oncology, April 12, 2013

5 Impact of pathologic complete response on disease-free survival in patients with esophagogastric adenocarcinoma receiving preoperative docetaxel-based chemotherapy Annals of Oncology, April 19, 2013

6 Multicenter phase II study of S-1 and docetaxel combination chemotherapy for advanced or recurrent gastric cancer patients with peritoneal dissemination Cancer Chemotherapy and Pharmacology, April 1, 2013

7 Epirubicin, oxaliplatin, and capecitabine with or without panitumumab for patients with previously untreated advanced oesophagogastric cancer (REAL3): a randomised, open-label phase 3 trial The Lancet Oncology, April 23, 2013

8 Meat, fish, and esophageal cancer risk: a systematic review and dose-response meta-analysis Nutrition Reviews, April 16, 2013 Evidence Based Medicine Review Article

9 The safety and efficacy of peginterferon plus ribavirin in hepatitis C patients concomitant with malignancy other than hepatocellular carcinoma: a multicenter study Hepatology International, March 25, 2013

10 Efficacy, safety, and pharmacokinetics of imatinib dose escalation to 800mg/day in patients with advanced gastrointestinal stromal tumors Investigational New Drugs, April 18, 2013

11 Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis (HIPEC): the Danish experience Colorectal Disease, March 11, 2013

12 Robot Versus Laparoscopic Gastrectomy for Cancer by an Experienced Surgeon: Comparisons of Surgery, Complications, and Surgical Stress Annals of Surgical Oncology, March 26, 2013

13 Laparoscopic versus open resection of gastrointestinal stromal tumors of the stomach Surgical Endoscopy, April 15, 2013

14 Neoadjuvant Chemotherapy for Gastric Cancer: A Meta-Analysis of Randomized Controlled Trails Journal of Gastroenterology and Hepatology, March 5, 2013 Evidence Based Medicine Review Article

15 Changing patterns of anal canal carcinoma in the United States Journal of Clinical Oncology, March 22, 2013

16 A comparison of three treatment strategies for locally advanced and borderline resectable pancreatic cancer Journal of Gastrointestinal Oncology, April 26, 2013 Free full text

17 Treatment of hepatocellular carcinoma in Child-Pugh B patients Digestive and Liver Diseases, April 29, 2013

18 Vitamin D and the Epidemiology of Upper Gastrointestinal Cancers: A Critical Analysis of the Current Evidence Cancer Epidemiology, Biomarkers & Prevention, April 9, 2013 Evidence Based Medicine

19 Chemoradiotherapy with or without cetuximab in patients with oesophageal cancer (SCOPE1): a multicentre, phase 2/3 randomised trial The Lancet Oncology, April 26, 2013

20 Capecitabine and cisplatin with or without cetuximab for patients with previously untreated advanced gastric cancer (EXPAND): a randomised, open-label phase 3 trial The Lancet Oncology, April 23, 2013

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more

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GI Oncology News & Articles

Articles

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

HCC risk increased in patients with AIDS

RAB25 is a prognostic marker for ovarian cancer

Most Popular Oncology Articles

Other Topics in Oncology