Endocrine Oncology News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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D Scott Cunningham MD, PhD
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Articles

Latest (1) Full Text Articles (100) Focus on Bone

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

1 Tracheal invasion and perforation from advanced primary thyroid lymphoma: A case report and literature review American Journal of Otolaryngology, May 24, 2013

Prior Articles

2 Pheochromocytoma revealed by acute heart failure. When should we operate? Presented at the ESES Congress, Gothenburg May 25-26, 2012 Langenbeck's Archives of Surgery, May 22, 2013 Clinical Article

3 Resection of At-Risk Mesenteric Lymph Nodes Is Associated with Improved Survival in Patients with Small Bowel Neuroendocrine Tumors World Journal of Surgery, May 21, 2013 Review Article

4 Clinical implication of the BRAFV600E mutation in papillary thyroid carcinoma Full Text World Journal of Surgical Oncology, May 21, 2013 Review Article

5 Cytopathological review of patients that underwent thyroidectomies based on the diagnosis of papillary thyroid carcinoma by fine needle aspiration cytology but were later found to have benign tumors by histopathology Surgery Today, May 21, 2013 Review Article

6 The Clinical and Economic Burden of a Sustained Increase in Thyroid Cancer Incidence Cancer Epidemiology, Biomarkers & Prevention, May 20, 2013 Review Article

7 Tumor marker and measurement fluctuations may not reflect treatment efficacy in patients with medullary thyroid carcinoma on long-term RET inhibitor therapy Annals of Oncology, May 20, 2013 Review Article

8 Unbalanced estrogen metabolism in thyroid cancer International Journal of Cancer, May 20, 2013 Clinical Article
Exclusive Author Commentary

9 DNA methylation signatures identify biologically distinct thyroid cancer subtypes Journal of Clinical Endocrinology and Metabolism, May 17, 2013 Clinical Article

10 A comprehensive next generation sequencing based genetic testing strategy to improve diagnosis of inherited pheochromocytoma and paraganglioma Journal of Clinical Endocrinology and Metabolism, May 17, 2013 Review Article

11 Predicting difficult laryngoscopy in acromegalic patients undergoing surgery for excision of pituitary tumors: A comparison of extended Mallampati score with modified Mallampati classification Full Text Journal of Anaesthesiology Clinical Pharmacology, May 16, 2013 Clinical Article

12 The Biopsy-Proven Benign Thyroid Nodule: Is Long-Term Follow-Up Necessary? Journal of the American College of Surgeons, May 15, 2013 Clinical Article

13 Clinical and functional impact of TARBP2 over-expression in adrenocortical carcinoma Endocrine-Related Cancer, May 15, 2013 Clinical Article

14 Undifferentiated (Anaplastic) Thyroid Carcinoma and Iodine Intake in Salta, Argentina Endocrine Pathology, May 15, 2013 Review Article

15 Advanced medullary thyroid cancer: pathophysiology and management Full Text Cancer Management and Research, May 14, 2013 Clinical Article

16 Tumour Suppressor Role of the CL2/DRO1/CCDC80 Gene in Thyroid Carcinogenesis Journal of Clinical Endocrinology and Metabolism, May 14, 2013 Review Article

17 Diabetes And Cancer: Two Diseases With Obesity As A Common Risk Factor Diabetes, Obesity and Metabolism, May 14, 2013 Review Article

18 Hints to the Diagnosis of Mixed Acinar-Endocrine Carcinoma on Pancreatic Fine-Needle Aspiration: Avoiding a Potential Diagnostic Pitfall Acta Cytologica, May 14, 2013

19 Treatment with docetaxel and cisplatin in advanced adrenocortical carcinoma, a phase II study British Journal of Cancer, May 13, 2013 Clinical Article

20 Nodal status of central lymph nodes as a negative prognostic factor for papillary thyroid carcinoma Journal of Surgical Oncology, May 13, 2013 Review Article

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Clinical Pearls in Oncology

The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 Increased costs of perioperative risk assessment for thyroid surgery in elderly people (over 80 years) presenting with benign disease Langenbeck's Archives of Surgery, April 12, 2013

2 Phase I study of sorafenib in combination with everolimus (RAD001) in patients with advanced neuroendocrine tumors Cancer Chemotherapy and Pharmacology, March 15, 2013

3 Evolving Approaches to Patients with Advanced Differentiated Thyroid Cancer Endocrine Reviews, April 11, 2013 Review Article

4 Therapeutic Implications of Diffuse Hepatic Uptake Following I-131 Therapy for Differentiated Thyroid Cancer Endocrine Practice, April 1, 2013 Review Article

5 The targeted therapy revolution in neuroendocrine tumors: in search of biomarkers for patient selection and response evaluation Cancer and Metastasis Reviews, April 18, 2013 Review Article

6 Selective use of RAI for ablation and adjuvant therapy after total thyroidectomy for differentiated thyroid cancer: A practical approach to clinical decision making Oral Oncology , April 25, 2013

7 Anaplastic thyroid cancer Oral Oncology , April 26, 2013

8 Urapidil in the Preoperative Treatment of Pheochromocytomas: A Safe and Cost-effective Method World Journal of Surgery, April 11, 2013

9 Medullary Thyroid Carcinoma Endocrine Practice, March 22, 2013

10 Liver Transplantation for Neuroendocrine Tumors in Europe-Results and Trends in Patient Selection: A 213-Case European Liver Transplant Registry Study Annals of Surgery, April 16, 2013

11 Comparative Outcomes of Laparoscopic and Open Adrenalectomy for Adrenocortical Carcinoma: Single, High-Volume Center Experience Annals of Surgical Oncology, April 9, 2013

12 Adrenocortical carcinoma: A population-based study on incidence and survival in the Netherlands since 1993 European Journal of Cancer, April 10, 2013 Review Article

13 The number of positive lymph nodes in the central compartment has prognostic impact in papillary thyroid cancer Langenbeck's Archives of Surgery, April 1, 2013 Review Article

14 Lessons learned and questions unanswered from use of multitargeted kinase inhibitors in medullary thyroid cancer Oral Oncology , April 16, 2013 Review Article

15 Redifferentiation and induction of tumor suppressors miR-122 and miR-375 by the PAX8/PPARγ fusion protein inhibits anaplastic thyroid cancer: a novel therapeutic strategy Cancer Gene Therapy, April 23, 2013
Exclusive Author Commentary

16 A comparison of Ki-67 and mitotic count as prognostic markers for metastatic pancreatic and midgut neuroendocrine neoplasms British Journal of Cancer, April 16, 2013

17 Pathological characteristics and clinical perspectives of papillary thyroid cancer: study of 714 patients European Archives of Oto-Rhino-Laryngology, April 12, 2013

18 Risk stratification in medullary thyroid cancer: Moving beyond static anatomic staging Oral Oncology , April 26, 2013 Review Article

19 Relapsing, remitting hypercortisolism in Cushings disease due to intratumoral hemorrhages in pituitary microadenoma Journal of Clinical Neuroscience, April 25, 2013

20 Therapeutic strategies in the management of patients with metastatic anaplastic thyroid cancer: review of the current literature Current Opinion in Oncology, April 9, 2013 Review Article

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more

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Endocrine Oncology News & Articles

Articles

Prior Articles

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

HCC risk increased in patients with AIDS

RAB25 is a prognostic marker for ovarian cancer

Most Popular Oncology Articles

Other Topics in Oncology