Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Oncology
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D Scott Cunningham MD, PhD
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161 Pharmacological Inhibition of Platelet-tumor Cell Cross-talk Prevents Platelet-induced Overexpression of Cyclooxygenase-2 in HT29 Human Colon Carcinoma Cells Molecular Pharmacology, April 24, 2013 Review Article
162 Response of liver metastases to preoperative radiochemotherapy in patients with locally advanced rectal cancer and resectable synchronous liver metastases Surgery, April 24, 2013 Clinical Article
163
Adequate lymph node recovery improves survival in colorectal cancer patients
Journal of Surgical Oncology, April 24, 2013
Clinical Article
Exclusive Author Commentary
164 Dietary Intervention with Mediterranean or Healthy Eating Goals has Similar Effects on Serum and Colon Concentrations of Carotenoids and Fatty Acids Cancer Prevention Research, April 23, 2013 Clinical Article
165 Gankyrin activates IL-8 to promote hepatic metastasis of colorectal cancer Cancer Research, April 23, 2013 Clinical Article
166 Identification of two new HLA-A*0201-restricted cytotoxic T lymphocyte epitopes from colorectal carcinoma-associated antigen PLAC1/CP1 Journal of Gastroenterology, April 23, 2013 Review Article
167 Differential expression of colon cancer associated transcript1 (CCAT1) along the colonic adenoma-carcinoma sequence Full Text BMC Cancer, April 23, 2013 Clinical Article
168 Fifteen-year-old colon cancer patient with a 10-year history of ulcerative colitis Full Text World Journal of Gastroenterology, April 23, 2013
169 Special AT-rich sequence-binding protein 1 promotes cell growth and metastasis in colorectal cancer Full Text World Journal of Gastroenterology, April 23, 2013 Review Article
170 HY-1 induce G2/M cell cycle arrest in human colon cancer cells via ATR-Chk1-Cdc25C and Weel pathways Cancer Science, April 23, 2013 Clinical Article
171 Bisphosphonate Use and Risk of Colorectal Cancer: A Systematic Review and Meta-analysis British Journal of Clinical Pharmacology, April 23, 2013 Evidence Based Medicine Review Article
172 Metachronous colorectal cancer in Taiwan: analyzing 20 years of data from Taiwan Cancer Registry International Journal of Clinical Oncology, April 23, 2013 Clinical Article
173 The aspartate aminotransferase to platelet ratio before chemotherapy predicts adverse events for FOLFOX and XELOX regimens including bevacizumab as the first-line therapy for stage IV, recurrent and metastatic colorectal cancer Full Text Journal of Gastrointestinal Oncology, April 23, 2013 Clinical Article
174 Oxidative DNA damage and β-catenin expression in colorectal cancer evolution International Journal of Colorectal Disease, April 23, 2013 Evidence Based Medicine Review Article
175 Are Right-Sided Colectomy Outcomes Different From Left-Sided Colectomy Outcomes?: Study of Patients With Colon Cancer in the ACS NSQIP Database JAMA Surgery, April 23, 2013 Clinical Article
176 Transanal Drainage to Treat Anastomotic Leaks After Low Anterior Resection for Rectal Cancer: A Valuable Option Diseases of the Colon and Rectum, April 23, 2013 Review Article Clinical Article
177 Association between physical activity and mortality in colorectal cancer: A meta-analysis of prospective cohort studies International Journal of Cancer, April 22, 2013 Review Article
178 Association of metformin use with cancer incidence and mortality: A meta-analysis Cancer Epidemiology, April 22, 2013 Review Article
179 Screening Participation Predictors for People at Familial Risk of Colorectal Cancer: A Systematic Review American Journal of Preventive Medicine, April 22, 2013 Evidence Based Medicine Review Article
180 Modern multidisciplinary treatment of rectal cancer based on staging with magnetic resonance imaging leads to excellent local control, but distant control remains a challenge European Journal of Cancer, April 22, 2013 Clinical Article
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summary1 Association between physical activity and mortality in colorectal cancer: A meta-analysis of prospective cohort studies International Journal of Cancer, April 22, 2013 Review Article
2 A randomised phase III intergroup trial comparing high-dose infusional 5-fluorouracil with or without folinic acid with standard bolus 5-fluorouracil/folinic acid in the adjuvant treatment of stage III colon cancer: The Pan-European Trial in Adjuvant Colon Cancer 2 study European Journal of Cancer, April 19, 2013
3 Management of stage Ii colon cancer - the use of molecular biomarkers for adjuvant therapy decision BMC Gastroenterology, March 19, 2013 Free full text
4 The beneficial effect of palliative resection in metastatic colorectal cancer British Journal of Cancer, March 14, 2013
5 Coffee consumption and risk of colorectal cancer: a dose-response analysis of observational studies Cancer Causes and Control, April 9, 2013 Review Article
6 Dietary Intervention with Mediterranean or Healthy Eating Goals has Similar Effects on Serum and Colon Concentrations of Carotenoids and Fatty Acids Cancer Prevention Research, April 23, 2013
7 Aflibercept Clinical Cancer Research, April 4, 2013
8 MicroRNA-215 inhibits relapse of colorectal cancer patients following radical surgery Medical Oncology, April 2, 2013
9 Current and emerging surveillance strategies to expand the window of opportunity for curative treatment after surgery in colorectal cancer Expert Review of Anticancer Therapy, April 19, 2013
10 A randomized, placebo-controlled phase 2 study of ganitumab or conatumumab in combination with FOLFIRI for second-line treatment of mutant KRAS metastatic colorectal cancer Annals of Oncology, March 22, 2013
11 Results of adjuvant FOLFOX regimens in stage III colorectal cancer patients: Retrospective analysis of 667 patients Oncology, February 8, 2013
12 Associations Between Cigarette Smoking Status and Colon Cancer Prognosis Among Participants in North Central Cancer Treatment Group Phase III Trial N0147 Journal of Clinical Oncology, April 4, 2013
13 Randomized controlled trial of cetuximab plus chemotherapy for patients with KRAS wild-type unresectable colorectal liver-limited metastases Journal of Clinical Oncology, April 15, 2013
14 Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial Clinical Cancer Research, April 18, 2013
15 Neoadjuvant FOLFIRI+bevacizumab in patients with resectable liver metastases from colorectal cancer: a phase 2 trial British Journal of Cancer, April 9, 2013
16 Promoter CPG island hypermethylation of the DNA repair enzyme MGMT predicts clinical response to dacarbazine in a phase II study for metastatic colorectal cancer Clinical Cancer Research, April 8, 2013
17 A randomised phase III intergroup trial comparing high-dose infusional 5-fluorouracil with or without folinic acid with standard bolus 5-fluorouracil/folinic acid in the adjuvant treatment of stage III colon cancer: The Pan-European Trial in Adjuvant Colon Cancer 2 study European Journal of Cancer, April 11, 2013
18 Androgen deprivation therapy and the risk of colorectal cancer in patients with prostate cancer Cancer Causes and Control, April 8, 2013
19 Oral bisphosphonate use and colorectal cancer incidence in the Womens Health Initiative Journal of Bone and Mineral Research, March 25, 2013
20 Liver Transplantation for Nonresectable Liver Metastases From Colorectal Cancer Annals of Surgery, April 15, 2013
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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