Oncology - Colorectal Cancer/Polyps News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (10) Full Text Articles (362) Focus on Bone

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

141 Can selenium levels act as a marker of colorectal cancer risk Full Text BMC Cancer, May 1, 2013 Clinical Article

142 Rural vs Urban Residence Affects Risk-Appropriate Colorectal Cancer Screening Clinical Gastroenterology and Hepatology , May 1, 2013 Clinical Article

143 ERK and AKT signaling cooperate to translationally regulate survivin expression for metastatic progression of colorectal cancer Oncogene, May 1, 2013 Clinical Article

144 Twist2 is a valuable prognostic biomarker for colorectal cancer Full Text World Journal of Gastroenterology, May 1, 2013 Clinical Article

145 Angiogenin outperforms VEGF, EPCs cells and CECs in predicting Dukes and AJCC stage in colorectal cancer European Journal of Clinical Investigation, May 1, 2013 Clinical Article

146 Novel adenoviral vector induces T-cell responses despite anti-adenoviral neutralizing antibodies in colorectal cancer patients Cancer Immunology, Immunotherapy, May 1, 2013 Clinical Article

147 The Role of ERK2 in Colorectal Carcinogenesis Is Partly Regulated by TRAPPC4 Molecular Carcinogenesis, May 1, 2013 Clinical Article

148 Colorectal Cancer Cells Refractory to Anti-VEGF Treatment Are Vulnerable to Glycolytic Blockade due to Persistent Impairment of Mitochondria Molecular Cancer Therapeutics, May 1, 2013 Clinical Article

149 Differential lymph node retrieval in rectal cancer: associated factors and effect on survival Full Text Journal of Gastrointestinal Oncology, May 1, 2013 Clinical Article

150 Signature of microsatellite instability, KRAS and BRAF gene mutations in German patients with locally advanced rectal adenocarcinoma before and after neoadjuvant 5-FU radiochemotherapy Full Text Journal of Gastrointestinal Oncology, May 1, 2013 Clinical Article

151 Patient satisfaction with breast and colorectal cancer survivorship care plans Clinical Journal of Oncology Nursing, May 1, 2013 Clinical Article

152 Predictive and prognostic role of BRAF mutation in metastatic colorectal cancer patients treated with anti- epidermal growth factor receptor monoclonal antibodies: A meta-analysis Journal of Digestive Diseases, April 30, 2013 Review Article

153 An analysis of the treatment effect of panitumumab on overall survival from a phase 3, randomized, controlled, multicenter trial (20020408) in patients with chemotherapy refractory metastatic colorectal cancer Targeted Oncology, April 30, 2013 Clinical Article

154 Palliative resection of the primary tumour in patients with Stage IV colorectal cancer: Systematic review and meta-analysis of the early outcome after laparoscopic and open colectomy Colorectal Disease, April 30, 2013 Clinical Article

155 γ-Glutamyl transpeptidase level is a novel adverse prognostic indicator in human metastatic colorectal cancer Colorectal Disease, April 30, 2013 Review Article

156 Are high initial CEA and CA 19-9 levels associated with the presence of K-ras mutation in patients with metastatic colorectal cancer Tumor Biology, April 30, 2013 Clinical Article

157 Serum miR-21 and miR-92a as biomarkers in the diagnosis and prognosis of colorectal cancer Tumor Biology, April 30, 2013 Clinical Article

158 Large variation between hospitals in follow-up for colorectal cancer in southern Netherlands International Journal of Colorectal Disease, April 30, 2013 Clinical Article

159 Impact of KRAS, BRAF and PI3KCA mutations in rectal carcinomas treated with neoadjuvant radiochemotherapy and surgery Full Text BMC Cancer, April 30, 2013 Review Article

160 SPROUTY2 is a β-catenin and FOXO3a target gene indicative of poor prognosis in colon cancer Oncogene, April 30, 2013 Review Article

50 available pages First Previous 8 9 10 11 12 13 14 15 16 17 Next Last

Clinical Pearls in Oncology

The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 Association between physical activity and mortality in colorectal cancer: A meta-analysis of prospective cohort studies International Journal of Cancer, April 22, 2013 Review Article

2 A randomised phase III intergroup trial comparing high-dose infusional 5-fluorouracil with or without folinic acid with standard bolus 5-fluorouracil/folinic acid in the adjuvant treatment of stage III colon cancer: The Pan-European Trial in Adjuvant Colon Cancer 2 study European Journal of Cancer, April 19, 2013

3 Management of stage Ii colon cancer - the use of molecular biomarkers for adjuvant therapy decision BMC Gastroenterology, March 19, 2013 Free full text

4 The beneficial effect of palliative resection in metastatic colorectal cancer British Journal of Cancer, March 14, 2013

5 Coffee consumption and risk of colorectal cancer: a dose-response analysis of observational studies Cancer Causes and Control, April 9, 2013 Review Article

6 Dietary Intervention with Mediterranean or Healthy Eating Goals has Similar Effects on Serum and Colon Concentrations of Carotenoids and Fatty Acids Cancer Prevention Research, April 23, 2013

7 Aflibercept Clinical Cancer Research, April 4, 2013

8 MicroRNA-215 inhibits relapse of colorectal cancer patients following radical surgery Medical Oncology, April 2, 2013

9 Current and emerging surveillance strategies to expand the window of opportunity for curative treatment after surgery in colorectal cancer Expert Review of Anticancer Therapy, April 19, 2013

10 A randomized, placebo-controlled phase 2 study of ganitumab or conatumumab in combination with FOLFIRI for second-line treatment of mutant KRAS metastatic colorectal cancer Annals of Oncology, March 22, 2013

11 Results of adjuvant FOLFOX regimens in stage III colorectal cancer patients: Retrospective analysis of 667 patients Oncology, February 8, 2013

12 Associations Between Cigarette Smoking Status and Colon Cancer Prognosis Among Participants in North Central Cancer Treatment Group Phase III Trial N0147 Journal of Clinical Oncology, April 4, 2013

13 Randomized controlled trial of cetuximab plus chemotherapy for patients with KRAS wild-type unresectable colorectal liver-limited metastases Journal of Clinical Oncology, April 15, 2013

14 Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial Clinical Cancer Research, April 18, 2013

15 Neoadjuvant FOLFIRI+bevacizumab in patients with resectable liver metastases from colorectal cancer: a phase 2 trial British Journal of Cancer, April 9, 2013

16 Promoter CPG island hypermethylation of the DNA repair enzyme MGMT predicts clinical response to dacarbazine in a phase II study for metastatic colorectal cancer Clinical Cancer Research, April 8, 2013

17 A randomised phase III intergroup trial comparing high-dose infusional 5-fluorouracil with or without folinic acid with standard bolus 5-fluorouracil/folinic acid in the adjuvant treatment of stage III colon cancer: The Pan-European Trial in Adjuvant Colon Cancer 2 study European Journal of Cancer, April 11, 2013

18 Androgen deprivation therapy and the risk of colorectal cancer in patients with prostate cancer Cancer Causes and Control, April 8, 2013

19 Oral bisphosphonate use and colorectal cancer incidence in the Womens Health Initiative Journal of Bone and Mineral Research, March 25, 2013

20 Liver Transplantation for Nonresectable Liver Metastases From Colorectal Cancer Annals of Surgery, April 15, 2013

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more

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Oncology - Colorectal Cancer/Polyps News & Articles

Articles

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

HCC risk increased in patients with AIDS

RAB25 is a prognostic marker for ovarian cancer

Most Popular Oncology Articles

Other Topics in Oncology