Oncology - Colorectal Cancer/Polyps News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (10) Full Text Articles (362) Focus on Neurologic

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

581 Increased Risk of Advanced Neoplasms Among Asymptomatic Siblings of Patients With Colorectal Cancer Gastroenterology, March 7, 2013 Clinical Article

582 CD44-positive cancer stem cells expressing cellular prion protein contribute to metastatic capacity in colorectal cancer Cancer Research, March 7, 2013 Clinical Article

583 Fifteen different 18F-FDG PET/CT qualitative and quantitative parameters investigated as pathological response predictors of locally advanced rectal cancer treated by neoadjuvant chemoradiation therapy European Journal of Nuclear Medicine & Molecular Imaging, March 7, 2013 Clinical Article

584 Harms of colonoscopy in a colorectal cancer screening programme with faecal occult blood test: A population-based cohort study Digestive and Liver Diseases, March 5, 2013 Clinical Article

585 One-Stage Hepatectomy Following Portal Vein Embolization for Colorectal Liver Metastasis World Journal of Surgery, March 4, 2013 Clinical Article

586 Robotic single-incision anterior resection for sigmoid colon cancer: access port creation and operative technique Surgical Endoscopy, March 4, 2013 Clinical Article

587 Patients with non-alcoholic fatty liver disease have higher risk of colorectal adenoma after negative baseline colonoscopy Colorectal Disease, March 1, 2013 Clinical Article

588 Use of FDG-PET or PET/CT to detect recurrent colorectal cancer in patients with elevated CEA: a systematic review and meta-analysis International Journal of Colorectal Disease, March 1, 2013 Evidence Based Medicine Review Article

589 Frequent epigenetic silencing of PCDH10 by methylation in human colorectal cancer Journal of Cancer Research & Clinical Oncology, March 1, 2013 Clinical Article

590 Genetic variations in the TGF{beta} signaling pathway, smoking and risk of colorectal cancer in a Chinese population Carcinogenesis, March 1, 2013 Clinical Article

591 PPP1R13L variant associated with prognosis for patients with rectal cancer Journal of Cancer Research & Clinical Oncology, February 28, 2013 Clinical Article

592 Evaluation of a Multimodality MR/US Coregistration System for Investigation of Hepatic Metastases from Colorectal Cancer Journal of Vascular and Interventional Radiology, February 25, 2013 Clinical Article

593 Polymorphisms in genes of APE1, PARP1, and XRCC1: risk and prognosis of colorectal cancer in a Northeast Chinese population Medical Oncology, February 25, 2013 Review Article

594 Delta-catenin promotes the proliferation and invasion of colorectal cancer cells by binding to E-cadherin in a competitive manner with p120 catenin Targeted Oncology, February 22, 2013 Clinical Article

595 Associations between Red Meat and Risks for Colon and Rectal Cancer Depend on the Type of Red Meat Consumed The Journal of Nutrition, February 22, 2013 Clinical Article

596 Clinical implications of initial FDG-PET/CT in locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy Cancer Chemotherapy and Pharmacology, February 21, 2013 Clinical Article

597 Impact of the MTHFR C677T polymorphism on colorectal cancer in a population with low genetic variability International Journal of Colorectal Disease, February 21, 2013 Review Article

598 Conditionally replicative adenovirus-based mda-7/IL-24 expression enhances sensitivity of colon cancer cells to 5-fluorouracil and doxorubicin Journal of Gastroenterology, February 21, 2013 Review Article

599 Expression and prognostic significance of GATA-binding protein 2 in colorectal cancer Medical Oncology, February 21, 2013 Clinical Article

600 Secondary mucosa-associated lymphoid tissue (MALT) lymphoma of the colon Medical Oncology, February 20, 2013 Review Article

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Clinical Pearls in Oncology

The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 Association between physical activity and mortality in colorectal cancer: A meta-analysis of prospective cohort studies International Journal of Cancer, April 22, 2013 Review Article

2 A randomised phase III intergroup trial comparing high-dose infusional 5-fluorouracil with or without folinic acid with standard bolus 5-fluorouracil/folinic acid in the adjuvant treatment of stage III colon cancer: The Pan-European Trial in Adjuvant Colon Cancer 2 study European Journal of Cancer, April 19, 2013

3 Management of stage Ii colon cancer - the use of molecular biomarkers for adjuvant therapy decision BMC Gastroenterology, March 19, 2013 Free full text

4 The beneficial effect of palliative resection in metastatic colorectal cancer British Journal of Cancer, March 14, 2013

5 Coffee consumption and risk of colorectal cancer: a dose-response analysis of observational studies Cancer Causes and Control, April 9, 2013 Review Article

6 Dietary Intervention with Mediterranean or Healthy Eating Goals has Similar Effects on Serum and Colon Concentrations of Carotenoids and Fatty Acids Cancer Prevention Research, April 23, 2013

7 Aflibercept Clinical Cancer Research, April 4, 2013

8 MicroRNA-215 inhibits relapse of colorectal cancer patients following radical surgery Medical Oncology, April 2, 2013

9 Current and emerging surveillance strategies to expand the window of opportunity for curative treatment after surgery in colorectal cancer Expert Review of Anticancer Therapy, April 19, 2013

10 A randomized, placebo-controlled phase 2 study of ganitumab or conatumumab in combination with FOLFIRI for second-line treatment of mutant KRAS metastatic colorectal cancer Annals of Oncology, March 22, 2013

11 Results of adjuvant FOLFOX regimens in stage III colorectal cancer patients: Retrospective analysis of 667 patients Oncology, February 8, 2013

12 Associations Between Cigarette Smoking Status and Colon Cancer Prognosis Among Participants in North Central Cancer Treatment Group Phase III Trial N0147 Journal of Clinical Oncology, April 4, 2013

13 Randomized controlled trial of cetuximab plus chemotherapy for patients with KRAS wild-type unresectable colorectal liver-limited metastases Journal of Clinical Oncology, April 15, 2013

14 Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial Clinical Cancer Research, April 18, 2013

15 Neoadjuvant FOLFIRI+bevacizumab in patients with resectable liver metastases from colorectal cancer: a phase 2 trial British Journal of Cancer, April 9, 2013

16 Promoter CPG island hypermethylation of the DNA repair enzyme MGMT predicts clinical response to dacarbazine in a phase II study for metastatic colorectal cancer Clinical Cancer Research, April 8, 2013

17 A randomised phase III intergroup trial comparing high-dose infusional 5-fluorouracil with or without folinic acid with standard bolus 5-fluorouracil/folinic acid in the adjuvant treatment of stage III colon cancer: The Pan-European Trial in Adjuvant Colon Cancer 2 study European Journal of Cancer, April 11, 2013

18 Androgen deprivation therapy and the risk of colorectal cancer in patients with prostate cancer Cancer Causes and Control, April 8, 2013

19 Oral bisphosphonate use and colorectal cancer incidence in the Womens Health Initiative Journal of Bone and Mineral Research, March 25, 2013

20 Liver Transplantation for Nonresectable Liver Metastases From Colorectal Cancer Annals of Surgery, April 15, 2013

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more

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Oncology - Colorectal Cancer/Polyps News & Articles

Articles

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

HCC risk increased in patients with AIDS

RAB25 is a prognostic marker for ovarian cancer

Most Popular Oncology Articles

Other Topics in Oncology