Oncology - Colorectal Cancer/Polyps News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (10) Full Text Articles (362) Focus on Renal

Ranked, sorted, and summarized by MDLinx editors from the latest literature

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561 A correlation of the endoscopic characteristics of colonic laterally spreading tumours with genetic alterations European Journal of Gastroenterology & Hepatology, March 1, 2013 Review Article

562 Clinical significance of microRNA-93 downregulation in human colon cancer European Journal of Gastroenterology & Hepatology, March 1, 2013 Review Article

563 The association of hospital volume with rectal cancer surgery outcomes International Journal of Colorectal Disease, March 1, 2013 Clinical Article

564 A Phase II Study of Temozolomide in Patients with Advanced Aerodigestive Tract and Colorectal Cancers and Methylation of the O6-Methylguanine-DNA Methyltransferase Promoter Molecular Cancer Therapeutics, March 1, 2013 Clinical Article

565 Genetic amplification of the NOTCH modulator LNX2 upregulates the WNT/{beta}-catenin pathway in colorectal cancer Cancer Research, March 1, 2013 Review Article

566 Multicenter phase I trial of the mitogen-activated protein kinase 1/2 inhibitor BAY 86-9766 in patients with advanced cancer Clinical Cancer Research, February 28, 2013

567 Bevacizumab use and risk of cardiovascular adverse events among elderly patients with colorectal cancer receiving chemotherapy: a population-based study Annals of Oncology, February 28, 2013 Clinical Article

568 Efficiency of Colorectal Cancer Care Among Veterans: Analysis of Treatment Wait Times at Veterans Affairs Medical Centers Journal of Oncology Practice, February 28, 2013 Clinical Article

569 Laparoscopy for extraperitoneal rectal cancer reduces short-term morbidity: Results of a systematic review and meta-analysis United European Gastroenterology Journal, February 28, 2013 Review Article Clinical Article

570 Patterns of adjuvant chemotherapy for stage II and III colon cancer in France and Italy Digestive and Liver Diseases, February 28, 2013 Clinical Article

571 A novel MEK inhibitor trametinib and other RB-reactivating agents enhance efficacy of 5-fluorouracil on human colon cancer cells Cancer Science, February 28, 2013 Clinical Article

572 Colorectal cancer cells refractory to anti-VEGF treatment are vulnerable to glycolytic blockade due to persistent impairment of mitochondria Molecular Cancer Therapeutics, February 28, 2013 Clinical Article

573 Age, is it an obstacle for older surgeons to learn laparoscopic approach for colorectal cancer Medical Oncology, February 27, 2013 Clinical Article

574 Chemotherapy ± Cetuximab Modulates Peripheral Immune Responses in Metastatic Colorectal Cancer Oncology, February 27, 2013 Clinical Article

575 Tandutinib inhibits the Akt/mTOR signaling pathway to inhibit colon cancer growth Molecular Cancer Therapeutics, February 27, 2013 Clinical Article

576 The relationship between epithelial and stromal TRIM28 expression predicts survival in colorectal cancer patients Journal of Gastroenterology and Hepatology, February 26, 2013 Review Article

577 Factors predicting worse prognosis in patients affected by pT3 N0 colon cancer: long-term results of a monocentric series of 137 radically resected patients in a 5-year period International Journal of Colorectal Disease, February 26, 2013 Review Article

578 Factors related with symptom duration until diagnosis and treatment of symptomatic colorectal cancer Full Text BMC Cancer, February 26, 2013

579 Crizotinib induces PUMA-dependent apoptosis in colon cancer cells Molecular Cancer Therapeutics, February 26, 2013 Clinical Article

580 Colorectal cancer mortality in Hong Kong of China, Japan, South Korea, and Singapore Full Text World Journal of Gastroenterology, February 25, 2013 Clinical Article

50 available pages First Previous 29 30 31 32 33 34 35 36 37 38 Next Last

Clinical Pearls in Oncology

The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 Association between physical activity and mortality in colorectal cancer: A meta-analysis of prospective cohort studies International Journal of Cancer, April 22, 2013 Review Article

2 A randomised phase III intergroup trial comparing high-dose infusional 5-fluorouracil with or without folinic acid with standard bolus 5-fluorouracil/folinic acid in the adjuvant treatment of stage III colon cancer: The Pan-European Trial in Adjuvant Colon Cancer 2 study European Journal of Cancer, April 19, 2013

3 Management of stage Ii colon cancer - the use of molecular biomarkers for adjuvant therapy decision BMC Gastroenterology, March 19, 2013 Free full text

4 The beneficial effect of palliative resection in metastatic colorectal cancer British Journal of Cancer, March 14, 2013

5 Coffee consumption and risk of colorectal cancer: a dose-response analysis of observational studies Cancer Causes and Control, April 9, 2013 Review Article

6 Dietary Intervention with Mediterranean or Healthy Eating Goals has Similar Effects on Serum and Colon Concentrations of Carotenoids and Fatty Acids Cancer Prevention Research, April 23, 2013

7 Aflibercept Clinical Cancer Research, April 4, 2013

8 MicroRNA-215 inhibits relapse of colorectal cancer patients following radical surgery Medical Oncology, April 2, 2013

9 Current and emerging surveillance strategies to expand the window of opportunity for curative treatment after surgery in colorectal cancer Expert Review of Anticancer Therapy, April 19, 2013

10 A randomized, placebo-controlled phase 2 study of ganitumab or conatumumab in combination with FOLFIRI for second-line treatment of mutant KRAS metastatic colorectal cancer Annals of Oncology, March 22, 2013

11 Results of adjuvant FOLFOX regimens in stage III colorectal cancer patients: Retrospective analysis of 667 patients Oncology, February 8, 2013

12 Associations Between Cigarette Smoking Status and Colon Cancer Prognosis Among Participants in North Central Cancer Treatment Group Phase III Trial N0147 Journal of Clinical Oncology, April 4, 2013

13 Randomized controlled trial of cetuximab plus chemotherapy for patients with KRAS wild-type unresectable colorectal liver-limited metastases Journal of Clinical Oncology, April 15, 2013

14 Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial Clinical Cancer Research, April 18, 2013

15 Neoadjuvant FOLFIRI+bevacizumab in patients with resectable liver metastases from colorectal cancer: a phase 2 trial British Journal of Cancer, April 9, 2013

16 Promoter CPG island hypermethylation of the DNA repair enzyme MGMT predicts clinical response to dacarbazine in a phase II study for metastatic colorectal cancer Clinical Cancer Research, April 8, 2013

17 A randomised phase III intergroup trial comparing high-dose infusional 5-fluorouracil with or without folinic acid with standard bolus 5-fluorouracil/folinic acid in the adjuvant treatment of stage III colon cancer: The Pan-European Trial in Adjuvant Colon Cancer 2 study European Journal of Cancer, April 11, 2013

18 Androgen deprivation therapy and the risk of colorectal cancer in patients with prostate cancer Cancer Causes and Control, April 8, 2013

19 Oral bisphosphonate use and colorectal cancer incidence in the Womens Health Initiative Journal of Bone and Mineral Research, March 25, 2013

20 Liver Transplantation for Nonresectable Liver Metastases From Colorectal Cancer Annals of Surgery, April 15, 2013

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more

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Oncology - Colorectal Cancer/Polyps News & Articles

Articles

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

HCC risk increased in patients with AIDS

RAB25 is a prognostic marker for ovarian cancer

Most Popular Oncology Articles

Other Topics in Oncology