Neurologic Oncology News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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D Scott Cunningham MD, PhD
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Articles

Latest (7) Full Text Articles (257) Focus on Renal

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

1 GRIM-19 opposes reprogramming of glioblastoma cell metabolism via HIF1{alpha} destabilization Carcinogenesis, May 23, 2013 Clinical Article

2 β-blockers increase response to chemotherapy via direct antitumour and anti-angiogenic mechanisms in neuroblastoma British Journal of Cancer, May 23, 2013 Clinical Article

3 Prognostic role for diffusion-weighted imaging of pediatric optic pathway glioma Journal of Neuro-Oncology, May 23, 2013 Clinical Article

4 Blood-based biomarkers for malignant gliomas Journal of Neuro-Oncology, May 23, 2013 Clinical Article

5 Defining pseudoprogression in glioblastoma multiforme European Journal of Neurology, May 23, 2013 Review Article

6 Pathologic and gene expression features of metastatic melanomas to the brain Cancer, May 23, 2013 Review Article

7 Refined brain tumor diagnostics and stratified therapies: the requirement for a multidisciplinary approach Acta Neuropathologica, May 23, 2013 Review Article

Prior Articles

8 The expression of cytoglobin as a prognostic factor in gliomas: a retrospective analysis of 88 patients Full Text BMC Cancer, May 22, 2013 Clinical Article

9 Anticancer activity of tolfenamic acid in medulloblastoma: a preclinical study Tumor Biology, May 22, 2013 Clinical Article

10 Health-related quality of life in patients with brain tumors: limitations and additional outcome measures Current Neurology and Neuroscience Reports, May 22, 2013 Clinical Article

11 Downregulation of miR-452 Promotes Stem-like traits and Tumorigenicity of Gliomas Clinical Cancer Research, May 22, 2013 Review Article

12 Ganglioneuroma in the papilla of Vater with neurofibromatosis type 1: report of a case Surgery Today, May 22, 2013

13 The impact of improved treatment strategies on overall survival in glioblastoma patients Acta Neurochirurgica, May 22, 2013 Review Article

14 Intraventricular ganglioglioma prognosis and hydrocephalus: The largest case series and systematic literature review Acta Neurochirurgica, May 22, 2013 Review Article

15 ZIP4 is a novel molecular marker for glioma Neuro-Oncology, May 21, 2013

16 Phase I study of temozolomide combined with oral etoposide in children with malignant glial tumors Journal of Neuro-Oncology, May 21, 2013 Clinical Article

17 Prediagnostic body weight and survival in high grade glioma Journal of Neuro-Oncology, May 21, 2013 Clinical Article

18 Histopathological correlates with survival in reoperated glioblastomas Journal of Neuro-Oncology, May 21, 2013 Clinical Article

19 O6-methylguanine-DNA methyltransferase (MGMT) immunohistochemistry as a predictor of resistance to temozolomide in primary CNS lymphoma Journal of Neuro-Oncology, May 21, 2013 Clinical Article

20 Cognitive rehabilitation for early post-surgery inpatients affected by primary brain tumor: a randomized, controlled trial Journal of Neuro-Oncology, May 21, 2013 Clinical Article

50 available pages FirstPrevious 1 2 3 4 5 6 7 8 9 10 Next Last

Clinical Pearls in Oncology

The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 Secondary hematological malignancies associated with temozolomide in patients with glioma Neuro-Oncology, March 26, 2013

2 Alphavbeta3 integrin and fibroblast growth factor receptor 1 (FGFR1): Prognostic factors in a phase I-II clinical trial associating continuous administration of tipifarnib with radiotherapy for patients with newly diagnosed glioblastoma European Journal of Cancer, April 11, 2013

3 Serum GFAP autoantibody as an ELISA-detectable glioma marker Tumor Biology, April 19, 2013

4 Phase 2 study of dose-intense temozolomide in recurrent glioblastoma Neuro-Oncology, April 9, 2013

5 Glioblastoma Resistance to Anti-VEGF Therapy: Has the Challenge Been MET Clinical Cancer Research, April 3, 2013

6 Phase II Study of Bevacizumab and Temsirolimus Combination Therapy for Recurrent Glioblastoma Multiforme Anticancer Research, April 9, 2013

7 Ex Vivo Activation of CD56+ Immune Cells That Eradicate Neuroblastoma Cancer Research, April 19, 2013

8 Molecular Pathways: Radiation-Induced Cognitive Impairment Clinical Cancer Research, April 2, 2013 Review Article

9 Hypofractionated Stereotactic Radiotherapy with the Hypoxic Sensitizer AK-2123 (Sanazole) for Reirradiation of Brain Metastases: A Preliminary Feasibility Report Anticancer Research, April 12, 2013

10 New Approaches to Understand Cognitive Changes Associated With Chemotherapy for Non-Central Nervous System Tumors Journal of Pain and Symptom Management, April 17, 2013 Review Article

11 Screening for brain metastases in patients with stage III non-small cell lung cancer: Is there additive value of magnetic resonance imaging above a contrast-enhanced computed tomography of the brain Lung Cancer, March 22, 2013

12 Seizures during the management of high-grade gliomas: clinical relevance to disease progression Journal of Neuro-Oncology, March 14, 2013 Review Article

13 The role of the CXCR4 cell surface chemokine receptor in glioma biology Journal of Neuro-Oncology, April 1, 2013

14 Chemotherapy plus radiotherapy versus radiotherapy alone in patients with anaplastic glioma: a systematic review and meta-analysis Journal of Cancer Research & Clinical Oncology, February 14, 2013 Evidence Based Medicine Review Article

15 Impact of radiotherapy delay on survival in glioblastoma Clinical and Translational Oncology, March 28, 2013

16 Phase I Trial, Pharmacokinetics, and Pharmacodynamics of Vandetanib and Dasatinib in Children with Newly Diagnosed Diffuse Intrinsic Pontine Glioma Clinical Cancer Research, March 29, 2013

17 A comparison of Ki-67 and mitotic count as prognostic markers for metastatic pancreatic and midgut neuroendocrine neoplasms British Journal of Cancer, April 16, 2013

18 The targeted therapy revolution in neuroendocrine tumors: in search of biomarkers for patient selection and response evaluation Cancer and Metastasis Reviews, April 18, 2013 Review Article

19 αvβ3 Integrin and Fibroblast growth factor receptor 1 (FGFR1): Prognostic factors in a phase I-II clinical trial associating continuous administration of Tipifarnib with radiotherapy for patients with newly diagnosed glioblastoma European Journal of Cancer, April 19, 2013

20 Headache as a risk factor for neurovascular events in pediatric brain tumor patients Neurology, April 3, 2013

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more

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Neurologic Oncology News & Articles

Articles

Prior Articles

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

HCC risk increased in patients with AIDS

RAB25 is a prognostic marker for ovarian cancer

Most Popular Oncology Articles

Other Topics in Oncology