Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Oncology
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D Scott Cunningham MD, PhD
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121 Alpha Internexin Expression Related with Molecular Characteristics in Adult Glioblastoma and Oligodendroglioma Full Text Journal of Korean Medical Science, April 25, 2013 Clinical Article
122 MR Imaging Predictors of Molecular Profile and Survival: Multi-institutional Study of the TCGA Glioblastoma Data Set Radiology, April 25, 2013 Clinical Article
123 Anatomic MR Imaging and Functional Diffusion Tensor Imaging of Peripheral Nerve Tumors and Tumorlike Conditions American Journal of Neuroradiology, April 25, 2013 Clinical Article
124 Limited plastic potential of the left ventral premotor cortex in speech articulation: Evidence From intraoperative awake mapping in glioma patients Human Brain Mapping, April 25, 2013 Clinical Article
125 Non-promoter DNA hypermethylation of Zygote Arrest 1 (ZAR1) in neuroblastomas Journal of Pediatric Surgery, April 25, 2013 Clinical Article
126 Modeling Tumor-Associated Edema in Gliomas during Anti-Angiogenic Therapy and Its Impact on Imageable Tumor Frontiers in Oncology, April 25, 2013 Review Article
127 Methylation of the TERT promoter and risk stratification of childhood brain tumours: an integrative genomic and molecular study The Lancet Oncology, April 24, 2013
128 The role of the WNT/β-catenin pathway in central nervous system primitive neuroectodermal tumours (CNS PNETs) British Journal of Cancer, April 24, 2013 Clinical Article
129
BLyS levels correlate with vaccine-induced antibody titers in patients with glioblastoma lymphodepleted by therapeutic temozolomide
Cancer Immunology, Immunotherapy, April 24, 2013
Clinical Article
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130 Differentiation between high and low grade tumours in paediatric patients by using apparent diffusion coefficients European Journal of Paediatric Neurology, April 24, 2013 Review Article
131 Sporadic intracranial haemangioblastomas: surgical outcome in a single institution series Acta Neurochirurgica, April 24, 2013 Review Article
132 Malignant astrocytomas of elderly patients lack favorable molecular markers: an analysis of the NOA-08 study collective Neuro-Oncology, April 23, 2013 Clinical Article
133 Vaccination with anti-idiotype antibody ganglidiomab mediates a GD2-specific anti-neuroblastoma immune response Cancer Immunology, Immunotherapy, April 23, 2013 Clinical Article
134 Advanced Neuroimaging Studies in a Patient with Brain Metastases from Transitional Cell Carcinoma of the Bladder Journal of Neuroimaging, April 23, 2013
135 Occurrence of extensive spherical amyloid deposits in a prolactin-secreting pituitary macroadenoma: a radiologic-pathologic correlation Annals of Diagnostic Pathology, April 23, 2013
136 Use of a tissue expander as a radio-protective spacer with a latissimus dorsi flap in the management of a peripheral primitive neuroectodermal tumour (pPNET) Journal of Plastic, Reconstructive & Aesthetic Surgery, April 23, 2013
137 Distinguishing Pseudoprogression From Progression in High-Grade Gliomas: A Brief Review of Current Clinical Practice and Demonstration of the Potential Value of 18F-FDG PET Clinical Nuclear Medicine , April 23, 2013
138 FoxG1 Interacts with Bmi1 to Regulate Self-Renewal and Tumorigenicity of Medulloblastoma Stem Cells Stem Cells, April 22, 2013 Clinical Article
139 Bevacizumab and Glioblastoma Multiforme: A Thrombosis and Bleeding Dilemma American Journal of Therapeutics, April 22, 2013 Review Article
140 Optimizing Contrast-Enhanced Magnetic Resonance Imaging Characterization of Brain Metastases: Relevance to Stereotactic Radiosurgery Neurosurgery, April 22, 2013 Clinical Article
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summary1 Secondary hematological malignancies associated with temozolomide in patients with glioma Neuro-Oncology, March 26, 2013
2 Alphavbeta3 integrin and fibroblast growth factor receptor 1 (FGFR1): Prognostic factors in a phase I-II clinical trial associating continuous administration of tipifarnib with radiotherapy for patients with newly diagnosed glioblastoma European Journal of Cancer, April 11, 2013
3 Serum GFAP autoantibody as an ELISA-detectable glioma marker Tumor Biology, April 19, 2013
4 Phase 2 study of dose-intense temozolomide in recurrent glioblastoma Neuro-Oncology, April 9, 2013
5 Glioblastoma Resistance to Anti-VEGF Therapy: Has the Challenge Been MET Clinical Cancer Research, April 3, 2013
6 Phase II Study of Bevacizumab and Temsirolimus Combination Therapy for Recurrent Glioblastoma Multiforme Anticancer Research, April 9, 2013
7 Ex Vivo Activation of CD56+ Immune Cells That Eradicate Neuroblastoma Cancer Research, April 19, 2013
8 Molecular Pathways: Radiation-Induced Cognitive Impairment Clinical Cancer Research, April 2, 2013 Review Article
9 Hypofractionated Stereotactic Radiotherapy with the Hypoxic Sensitizer AK-2123 (Sanazole) for Reirradiation of Brain Metastases: A Preliminary Feasibility Report Anticancer Research, April 12, 2013
10 New Approaches to Understand Cognitive Changes Associated With Chemotherapy for Non-Central Nervous System Tumors Journal of Pain and Symptom Management, April 17, 2013 Review Article
11 Screening for brain metastases in patients with stage III non-small cell lung cancer: Is there additive value of magnetic resonance imaging above a contrast-enhanced computed tomography of the brain Lung Cancer, March 22, 2013
12 Seizures during the management of high-grade gliomas: clinical relevance to disease progression Journal of Neuro-Oncology, March 14, 2013 Review Article
13 The role of the CXCR4 cell surface chemokine receptor in glioma biology Journal of Neuro-Oncology, April 1, 2013
14 Chemotherapy plus radiotherapy versus radiotherapy alone in patients with anaplastic glioma: a systematic review and meta-analysis Journal of Cancer Research & Clinical Oncology, February 14, 2013 Evidence Based Medicine Review Article
15 Impact of radiotherapy delay on survival in glioblastoma Clinical and Translational Oncology, March 28, 2013
16 Phase I Trial, Pharmacokinetics, and Pharmacodynamics of Vandetanib and Dasatinib in Children with Newly Diagnosed Diffuse Intrinsic Pontine Glioma Clinical Cancer Research, March 29, 2013
17 A comparison of Ki-67 and mitotic count as prognostic markers for metastatic pancreatic and midgut neuroendocrine neoplasms British Journal of Cancer, April 16, 2013
18 The targeted therapy revolution in neuroendocrine tumors: in search of biomarkers for patient selection and response evaluation Cancer and Metastasis Reviews, April 18, 2013 Review Article
19 αvβ3 Integrin and Fibroblast growth factor receptor 1 (FGFR1): Prognostic factors in a phase I-II clinical trial associating continuous administration of Tipifarnib with radiotherapy for patients with newly diagnosed glioblastoma European Journal of Cancer, April 19, 2013
20 Headache as a risk factor for neurovascular events in pediatric brain tumor patients Neurology, April 3, 2013
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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