Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Oncology
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D Scott Cunningham MD, PhD
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421 The caregivers perspective on the end-of-life phase of glioblastoma patients Journal of Neuro-Oncology, February 28, 2013 Review Article
422 Neuroanatomical target theory as a predictive model for radiation-induced cognitive decline Neurology, February 28, 2013 Clinical Article
423 Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations Acta Neuropathologica, February 28, 2013 Clinical Article
424 Cerebral Revascularization for Difficult Skull Base Tumors: A Contemporary Series of 18 Patients World Neurosurgery, February 27, 2013 Clinical Article
425 Disseminated glioneuronal tumor with neuropil-like islands of the spinal cord: A distinctive entity World Neurosurgery, February 27, 2013
426 Vasculogenic mimicry is a prognostic factor for postoperative survival in patients with glioblastoma Journal of Neuro-Oncology, February 27, 2013 Clinical Article
427 Evaluation of mini-mental status examination score after gamma knife radiosurgery as the first radiation treatment for brain metastases Journal of Neuro-Oncology, February 27, 2013 Clinical Article
428 Distant metastases in meningioma: an underestimated problem Journal of Neuro-Oncology, February 27, 2013 Clinical Article
429 FOXO3a Is A Major Target Of Inactivation By PI3K/AKT Signaling In Aggressive Neuroblastoma Cancer Research, February 27, 2013 Clinical Article
430 Use of poly dl-lactide-ε-caprolactone (Neurolac) conduit for enveloping traumatic neuromas European Journal of Plastic Surgery, February 26, 2013 Clinical Article
431 Morphologic MRI features, diffusion tensor imaging and radiation dosimetric analysis to differentiate pseudo-progression from early tumor progression Journal of Neuro-Oncology, February 26, 2013 Clinical Article
432 Expression of aquaporin 5 and the AQP5 polymorphism A(-1364)C in association with peritumoral brain edema in meningioma patients Journal of Neuro-Oncology, February 26, 2013 Clinical Article
433 Adult Cerebellar Glioblastoma: Understanding Survival and Prognostic Factors Using A Population-Based Database from 1973 - 2009 World Neurosurgery, February 26, 2013 Clinical Article
434 Combined Primary Tumor and Extracranial Metastasis Status as Constituent Factor of Prognostic Indices for Predicting the Overall Survival in Patients with Brain Metastases Full Text Journal of Korean Medical Science, February 26, 2013
435 Glutamine synthetase expression as a valuable marker of epilepsy and longer survival in newly diagnosed glioblastoma multiforme Neuro-Oncology, February 25, 2013 Clinical Article
436 MiR-106a is an independent prognostic marker in patients with glioblastoma Neuro-Oncology, February 25, 2013 Clinical Article
437 Focused Ultrasound Delivers Targeted Immune Cells To Metastatic Brain Tumors Cancer Research, February 25, 2013 Clinical Article
438 Harmine hydrochloride inhibits Akt phosphorylation and depletes the pool of cancer stem-like cells of glioblastoma Journal of Neuro-Oncology, February 25, 2013 Clinical Article
439 Validity of two recently-proposed prognostic grading indices for lung, gastro-intestinal, breast and renal cell cancer patients with radiosurgically-treated brain metastases Journal of Neuro-Oncology, February 25, 2013 Clinical Article
440 VP22 and cytosine deaminase fusion gene modified tissue-engineered neural stem cells for glioma therapy Journal of Cancer Research & Clinical Oncology, February 25, 2013 Review Article
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summary1 Secondary hematological malignancies associated with temozolomide in patients with glioma Neuro-Oncology, March 26, 2013
2 Alphavbeta3 integrin and fibroblast growth factor receptor 1 (FGFR1): Prognostic factors in a phase I-II clinical trial associating continuous administration of tipifarnib with radiotherapy for patients with newly diagnosed glioblastoma European Journal of Cancer, April 11, 2013
3 Serum GFAP autoantibody as an ELISA-detectable glioma marker Tumor Biology, April 19, 2013
4 Phase 2 study of dose-intense temozolomide in recurrent glioblastoma Neuro-Oncology, April 9, 2013
5 Glioblastoma Resistance to Anti-VEGF Therapy: Has the Challenge Been MET Clinical Cancer Research, April 3, 2013
6 Phase II Study of Bevacizumab and Temsirolimus Combination Therapy for Recurrent Glioblastoma Multiforme Anticancer Research, April 9, 2013
7 Ex Vivo Activation of CD56+ Immune Cells That Eradicate Neuroblastoma Cancer Research, April 19, 2013
8 Molecular Pathways: Radiation-Induced Cognitive Impairment Clinical Cancer Research, April 2, 2013 Review Article
9 Hypofractionated Stereotactic Radiotherapy with the Hypoxic Sensitizer AK-2123 (Sanazole) for Reirradiation of Brain Metastases: A Preliminary Feasibility Report Anticancer Research, April 12, 2013
10 New Approaches to Understand Cognitive Changes Associated With Chemotherapy for Non-Central Nervous System Tumors Journal of Pain and Symptom Management, April 17, 2013 Review Article
11 Screening for brain metastases in patients with stage III non-small cell lung cancer: Is there additive value of magnetic resonance imaging above a contrast-enhanced computed tomography of the brain Lung Cancer, March 22, 2013
12 Seizures during the management of high-grade gliomas: clinical relevance to disease progression Journal of Neuro-Oncology, March 14, 2013 Review Article
13 The role of the CXCR4 cell surface chemokine receptor in glioma biology Journal of Neuro-Oncology, April 1, 2013
14 Chemotherapy plus radiotherapy versus radiotherapy alone in patients with anaplastic glioma: a systematic review and meta-analysis Journal of Cancer Research & Clinical Oncology, February 14, 2013 Evidence Based Medicine Review Article
15 Impact of radiotherapy delay on survival in glioblastoma Clinical and Translational Oncology, March 28, 2013
16 Phase I Trial, Pharmacokinetics, and Pharmacodynamics of Vandetanib and Dasatinib in Children with Newly Diagnosed Diffuse Intrinsic Pontine Glioma Clinical Cancer Research, March 29, 2013
17 A comparison of Ki-67 and mitotic count as prognostic markers for metastatic pancreatic and midgut neuroendocrine neoplasms British Journal of Cancer, April 16, 2013
18 The targeted therapy revolution in neuroendocrine tumors: in search of biomarkers for patient selection and response evaluation Cancer and Metastasis Reviews, April 18, 2013 Review Article
19 αvβ3 Integrin and Fibroblast growth factor receptor 1 (FGFR1): Prognostic factors in a phase I-II clinical trial associating continuous administration of Tipifarnib with radiotherapy for patients with newly diagnosed glioblastoma European Journal of Cancer, April 19, 2013
20 Headache as a risk factor for neurovascular events in pediatric brain tumor patients Neurology, April 3, 2013
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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