Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
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1 Breast cancer phenotype, nodal status and palpability may be useful in the detection of overdiagnosed screening-detected breast cancers Annals of Oncology, May 21, 2013
2 Breast density and breast cancer risk by mammogram timing Cancer Epidemiology, Biomarkers & Prevention, May 21, 2013
3 Is it safe and efficacious for women with lymphedema secondary to breast cancer to lift heavy weights during exercise: a randomised controlled trial Journal of Cancer Survivorship, May 21, 2013 Clinical Article
4 Overdiagnosis in breast cancer screening: the importance of length of observation period and lead time Breast Cancer Research, May 21, 2013 Clinical Article
5 HER2/CEP17 ratio and HER2 immunohistochemistry predict clinical outcome after first-line trastuzumab plus taxane chemotherapy in patients with HER2 fluorescence in situ hybridization-positive metastatic breast cancer Cancer Chemotherapy and Pharmacology, May 21, 2013 Clinical Article
6 Fulvestrant regulates epidermal growth factor (EGF) family ligands to activate EGF receptor (EGFR) signaling in breast cancer cells Breast Cancer Research and Treatment, May 21, 2013 Review Article
7 Preoperative Serum C-Reactive Protein Levels and Early Breast Cancer by BMI and Menopausal Status Cancer Investigation, May 21, 2013 Review Article
8 Circulating tumor cell detection during chemotherapy in patients with breast cancer is not associated with plasma homocysteine levels Tumor Biology, May 21, 2013 Clinical Article
9 Overexpression of CRKL correlates with malignant cell proliferation in breast cancer Tumor Biology, May 21, 2013 Clinical Article
10 C282Y polymorphism in the HFE gene is associated with risk of breast cancer Tumor Biology, May 21, 2013 Clinical Article
11 Positive versus negative sentinel nodes in early breast cancer patients: Axillary or loco-regional relapse and survival. A study spanning 2000–2012 The Breast, May 21, 2013 Review Article
12 Trastuzumab therapy in Australia: Which patients with HER2+ metastatic breast cancer are assessed for cardiac function? The Breast, May 21, 2013 Clinical Article
13 Detection of disseminated tumor cells in locally advanced breast cancer patients before primary systemic therapy The Breast, May 21, 2013 Clinical Article
14 Caspase-2 is involved in cell death induction by taxanes in breast cancer cells Cancer Cell International, May 21, 2013 Clinical Article
15 Role of Galactography in the Early Diagnosis of Breast Cancer Breast Care, May 21, 2013 Review Article
16 Patients Anastrozole Compliance to Therapy (PACT) Program: Baseline Data and Patient Characteristics from a Population-Based, Randomized Study Evaluating Compliance to Aromatase Inhibitor Therapy in Postmenopausal Women with Hormone-Sensitive Early Breast Cancer Breast Care, May 21, 2013 Clinical Article
17 Effect of Endocrine Therapy on Quality of Life and Cognitive Functions in Patients with Breast Cancer Breast Care, May 21, 2013 Review Article
18 Chemotherapy-induced prospective memory impairment in patients with breast cancer Psycho-Oncology, May 21, 2013 Clinical Article
19 Relationship between cancer-related fatigue and personality in patients with breast cancer after chemotherapy Psycho-Oncology, May 21, 2013 Clinical Article
20 Quantitation of sentinel node metastatic burden and Her-2/neu over-expression accurately predicts residual axillary nodal involvement and extranodal disease in breast cancer European Journal of Surgical Oncology, May 21, 2013 Clinical Article
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summaryIndexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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