Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
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81 Repression of mammary adipogenesis by genistein limits mammosphere formation of human MCF-7 cells Journal of Endocrinology, May 14, 2013 Review Article
82 Survival times of women with metastatic breast cancer starting first-line chemotherapy in routine clinical practice versus contemporary randomised trials Internal Medicine Journal, May 14, 2013 Clinical Article
83 Small breast epithelial mucin tumor tissue expression is associated with increased risk of recurrence and death in triple-negative breast cancer patients Full Text Diagnostic Pathology, May 14, 2013 Clinical Article
84 Coffee and caffeine intake and breast cancer risk: An updated dose-response meta-analysis of 37 published studies Gynecologic Oncology, May 13, 2013 Evidence Based Medicine Clinical Article
85 Targeting FGFR With Dovitinib (TKI258): Preclinical and Clinical Data in Breast Cancer Clinical Cancer Research, May 13, 2013 Clinical Article
86 Metabolic factors and breast cancer risk in Korean women Cancer Causes and Control, May 13, 2013 Clinical Article
87 Intensity modulated proton therapy for postmastectomy radiation of bilateral implant reconstructed breasts: A treatment planning study Radiotherapy & Oncology, May 13, 2013 Clinical Article
88 Genetic ancestry modifies the association between genetic risk variants and breast cancer risk among Hispanic and non-Hispanic white women Carcinogenesis, May 13, 2013 Review Article Clinical Article
89 Characterization of Low Molecular Weight Protein Tyrosine Phosphatase Isoforms in Human Breast Cancer Epithelial Cell Lines Anticancer Research, May 13, 2013 Clinical Article
90 Evaluation of Current Prognostic and Predictive Markers in Breast Cancer: A Validation Study of Tissue Microarrays Anticancer Research, May 13, 2013 Clinical Article
91 TPD52 Represents a Survival Factor in ERBB2-Amplified Breast Cancer Cells Molecular Carcinogenesis, May 13, 2013 Clinical Article
92 Use of bisphosphonates in metastatic breast cancer: single institution review at the Dr. H. Bliss Murphy Cancer Centre Supportive Care in Cancer, May 13, 2013 Review Article Clinical Article
93 A pilot study of prospective memory functioning in early breast cancer survivors The Breast, May 13, 2013 Review Article Clinical Article
94 Detection of prognostic factors in metastatic breast cancer Journal of Research in Medical Sciences, May 13, 2013 Evidence Based Medicine Clinical Article
95 Prophylactic use of levonorgestrel-releasing intrauterine system in women with breast cancer treated with tamoxifen: a randomized controlled trial Obstetrics and Gynecology, May 13, 2013 Clinical Article
96 Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in Patients with Cytologically Proven Node-positive Breast Cancer at Diagnosis Annals of Surgical Oncology, May 13, 2013 Clinical Article
97 The Role of Nipple-Sparing Mastectomy in Breast Cancer: A Comprehensive Review of the Literature Plastic and Reconstructive Surgery, May 13, 2013 Review Article
98 Role of radiotherapy boost in women with ductal carcinoma in situ: A single-center experience in a series of 389 patients European Journal of Surgical Oncology, May 13, 2013 Review Article
99 Adipocytokines, inflammation, and breast cancer risk in postmenopausal women: a prospective study Cancer Epidemiology, Biomarkers & Prevention, May 10, 2013
100 Breast cancer risk following Hodgkin lymphoma radiotherapy in relation to menstrual and reproductive factors British Journal of Cancer, May 10, 2013
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summary1 Radiotherapy or tamoxifen after conserving surgery for breast cancers of excellent prognosis: British Association of Surgical Oncology (BASO) II trial European Journal of Cancer, April 2, 2013
2 Effect of low-dose tamoxifen after surgical excision of ductal intraepithelial neoplasia: results of a large retrospective monoinstitutional cohort study Annals of Oncology, April 1, 2013
3 Increased pathological complete response rate after a long-term neoadjuvant letrozole treatment in postmenopausal oestrogen and/or progesterone receptor-positive breast cancer British Journal of Cancer, April 16, 2013
4 Axillary dissection versus no axillary dissection in patients with sentinel-node micrometastases (IBCSG 23-01): a phase 3 randomised controlled trial The Lancet Oncology, March 12, 2013
5 Association of metformin use with cancer incidence and mortality: A meta-analysis Cancer Epidemiology, April 22, 2013 Review Article
6 Factors associated with surgical management following neoadjuvant therapy in patients with primary HER2-positive breast cancer: results from the NeoALTTO phase III trial Annals of Oncology, April 12, 2013
7 Neoadjuvant chemotherapy with paclitaxel and everolimus in breast cancer patients with non-responsive tumours to epirubicin/cyclophosphamide (EC)±bevacizumab: Results of the randomised GeparQuinto study (GBG 44) European Journal of Cancer, April 24, 2013
8 AVEREL: A randomized phase III trial evaluating bevacizumab in combination with docetaxel and trastuzumab as first-line therapy for HER2-positive locally recurrent/metastatic breast cancer Journal of Clinical Oncology, April 15, 2013
9 Estrogen plus progestin and breast cancer incidence and mortality in the Women's Health Initiative Observational Study Journal of the National Cancer Institute, April 4, 2013
10 Analysis in early stage triple-negative breast cancer treated with mastectomy without adjuvant radiotherapy: Patterns of failure and prognostic factors Cancer, April 12, 2013
11 Effect of body mass index on tumor characteristics and disease-free survival in patients from the HER2-positive adjuvant trastuzumab trial N9831 Cancer, April 19, 2013
12 Randomised phase 3 open-label trial of first-line treatment with gemcitabine in association with docetaxel or paclitaxel in women with metastatic breast cancer: a comparison of different schedules and treatments BMC Cancer, April 3, 2013 Free full text
13 Incidence of unilateral arm lymphoedema after breast cancer: a systematic review and meta-analysis The Lancet Oncology, April 9, 2013 Evidence Based Medicine Review Article
14 Magnitude of trastuzumab benefit in patients with HER2-positive, invasive lobular breast carcinoma: Results from the HERA Trial Journal of Clinical Oncology, April 25, 2013
15 Does night work increase the risk of breast cancer? A systematic review and meta-analysis of epidemiological studies Cancer Epidemiology, April 22, 2013 Review Article
16 Substantial breast cancer risk reduction and potential survival benefit after bilateral mastectomy when compared with surveillance in healthy BRCA1 and BRCA2 mutation carriers: a prospective analysis Annals of Oncology, April 16, 2013
17 Consensus on the regional lymph nodes irradiation in breast cancer Clinical and Translational Oncology, March 28, 2013
18 Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA study): overall survival results from a randomised, double-blind, placebo-controlled, phase 3 study The Lancet Oncology, April 19, 2013
19 Sedentary behavior, physical activity, and likelihood of breast cancer among black and white women: a report from the Southern Community Cohort Study Cancer Prevention Research, April 18, 2013
20 Incidence of unilateral arm lymphoedema after breast cancer: a systematic review and meta-analysis The Lancet Oncology, March 29, 2013 Review Article
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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