Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
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41 Evolution of sites of recurrence after early breast cancer over the last 20 years: implications for patient care and future research Breast Cancer Research and Treatment, May 20, 2013 Review Article
42 Tau proteins expressions in advanced breast cancer and its significance in taxane-containing neoadjuvant chemotherapy Medical Oncology, May 20, 2013 Review Article
43 Magnetic Resonance Imaging Enhancement Features Before and After Neoadjuvant Chemotherapy in Patients With Breast Cancer: A Predictive Value for Responders Journal of Computer Assisted Tomography, May 20, 2013 Clinical Article
44 New Breast Cancer Risk Variant Discovered at 10q25 in East Asian Women Cancer Epidemiology, Biomarkers & Prevention, May 20, 2013 Review Article
45 The Redox State of Cytochrome C Modulates Resistance to Methotrexate in Human MCF7 Breast Cancer Cells PLOS ONE, May 20, 2013 Review Article
46 Randomized controlled trial of toremifene 120 mg compared with exemestane 25 mg after prior treatment with a non-steroidal aromatase inhibitor in postmenopausal women with hormone receptor-positive metastatic breast cancer Full Text BMC Cancer, May 20, 2013 Clinical Article
47 Postdiagnosis supplement use and breast cancer prognosis in the After Breast Cancer Pooling Project Breast Cancer Research and Treatment, May 20, 2013 Clinical Article
48 Prognostic Value of Disseminated Tumor Cells in the Bone Marrow of Patients with Operable Primary Breast Cancer: A Long-term Follow-up Study Annals of Surgical Oncology, May 20, 2013 Clinical Article
49 Efficacy and safety of 12-weekly versus 4-weekly zoledronic acid for prolonged treatment of patients with bone metastases from breast cancer (ZOOM): a phase 3, open-label, randomised, non-inferiority trial The Lancet Oncology, May 17, 2013 Clinical Article
50 Individually tailored screening of breast cancer with genes, tumour phenotypes, clinical attributes, and conventional risk factors British Journal of Cancer, May 17, 2013
51 Influence of compliance on bone mineral density changes in postmenopausal women with early breast cancer on Anastrozole Journal of Cancer Research & Clinical Oncology, May 17, 2013 Clinical Article
52 Major changes in chemotherapy regimens administered to breast cancer patients during 2000-2008 in the Netherlands The Breast Journal, May 17, 2013 Clinical Article
53
Prognostic Factors for Male Breast Cancer: Similarity to Female Counterparts
Anticancer Research, May 17, 2013
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54 Frequent inactivation of cysteine dioxygenase type 1 contributes to survival of breast cancer cells and resistance to anthracyclines Clinical Cancer Research, May 17, 2013 Clinical Article
55 The effects of primary care on breast cancer mortality and incidence among Medicare beneficiaries Cancer, May 17, 2013 Clinical Article
56 Structural equation modeling for implementation intentions, cancer worry, and stages of mammography adoption Psycho-Oncology, May 17, 2013 Clinical Article
57 The role of versican in modulating breast cancer cell self-renewal Molecular Cancer Research, May 17, 2013 Clinical Article
58 Consistency and inconsistency in testing biomarkers in breast cancer. A GRELL study in cut-off variability in the Romance language countries The Breast, May 17, 2013 Review Article
59 Influence of ABCB1 polymorphisms and docetaxel pharmacokinetics on pathological response to neoadjuvant chemotherapy in breast cancer patients Breast Cancer Research and Treatment, May 17, 2013 Review Article
60 Ki-67 is a prognostic parameter in breast cancer patients: results of a large population-based cohort of a cancer registry Breast Cancer Research and Treatment, May 17, 2013 Clinical Article
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summary1 Radiotherapy or tamoxifen after conserving surgery for breast cancers of excellent prognosis: British Association of Surgical Oncology (BASO) II trial European Journal of Cancer, April 2, 2013
2 Effect of low-dose tamoxifen after surgical excision of ductal intraepithelial neoplasia: results of a large retrospective monoinstitutional cohort study Annals of Oncology, April 1, 2013
3 Increased pathological complete response rate after a long-term neoadjuvant letrozole treatment in postmenopausal oestrogen and/or progesterone receptor-positive breast cancer British Journal of Cancer, April 16, 2013
4 Axillary dissection versus no axillary dissection in patients with sentinel-node micrometastases (IBCSG 23-01): a phase 3 randomised controlled trial The Lancet Oncology, March 12, 2013
5 Association of metformin use with cancer incidence and mortality: A meta-analysis Cancer Epidemiology, April 22, 2013 Review Article
6 Factors associated with surgical management following neoadjuvant therapy in patients with primary HER2-positive breast cancer: results from the NeoALTTO phase III trial Annals of Oncology, April 12, 2013
7 Neoadjuvant chemotherapy with paclitaxel and everolimus in breast cancer patients with non-responsive tumours to epirubicin/cyclophosphamide (EC)±bevacizumab: Results of the randomised GeparQuinto study (GBG 44) European Journal of Cancer, April 24, 2013
8 AVEREL: A randomized phase III trial evaluating bevacizumab in combination with docetaxel and trastuzumab as first-line therapy for HER2-positive locally recurrent/metastatic breast cancer Journal of Clinical Oncology, April 15, 2013
9 Estrogen plus progestin and breast cancer incidence and mortality in the Women's Health Initiative Observational Study Journal of the National Cancer Institute, April 4, 2013
10 Analysis in early stage triple-negative breast cancer treated with mastectomy without adjuvant radiotherapy: Patterns of failure and prognostic factors Cancer, April 12, 2013
11 Effect of body mass index on tumor characteristics and disease-free survival in patients from the HER2-positive adjuvant trastuzumab trial N9831 Cancer, April 19, 2013
12 Randomised phase 3 open-label trial of first-line treatment with gemcitabine in association with docetaxel or paclitaxel in women with metastatic breast cancer: a comparison of different schedules and treatments BMC Cancer, April 3, 2013 Free full text
13 Incidence of unilateral arm lymphoedema after breast cancer: a systematic review and meta-analysis The Lancet Oncology, April 9, 2013 Evidence Based Medicine Review Article
14 Magnitude of trastuzumab benefit in patients with HER2-positive, invasive lobular breast carcinoma: Results from the HERA Trial Journal of Clinical Oncology, April 25, 2013
15 Does night work increase the risk of breast cancer? A systematic review and meta-analysis of epidemiological studies Cancer Epidemiology, April 22, 2013 Review Article
16 Substantial breast cancer risk reduction and potential survival benefit after bilateral mastectomy when compared with surveillance in healthy BRCA1 and BRCA2 mutation carriers: a prospective analysis Annals of Oncology, April 16, 2013
17 Consensus on the regional lymph nodes irradiation in breast cancer Clinical and Translational Oncology, March 28, 2013
18 Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA study): overall survival results from a randomised, double-blind, placebo-controlled, phase 3 study The Lancet Oncology, April 19, 2013
19 Sedentary behavior, physical activity, and likelihood of breast cancer among black and white women: a report from the Southern Community Cohort Study Cancer Prevention Research, April 18, 2013
20 Incidence of unilateral arm lymphoedema after breast cancer: a systematic review and meta-analysis The Lancet Oncology, March 29, 2013 Review Article
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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