Oncology - Bone/Cartilage News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (2) Full Text Articles (52) Focus on Pancreas

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

141 Prospective Histomorphometric and DXA Evaluation of Bone Remodeling in Imatinib-Treated CML Patients: Evidence for Site-Specific Skeletal Effects Journal of Clinical Endocrinology and Metabolism, January 3, 2013 Clinical Article

142 Osteosarcoma Phenotype Is Inhibited by 3,4-Methylenedioxy-β-nitrostyrene Sarcoma, January 3, 2013 Clinical Article

143 Prognostic Implications of miR-146b Expression and Its Functional Role in Papillary Thyroid Carcinoma Journal of Clinical Endocrinology and Metabolism, December 31, 2012

144 Nosocomial infections in leukemic and solid-tumor cancer patients: distribution, outcome and microbial spectrum of anaerobes Future Microbiology, December 26, 2012

145 p38 MAPK in Myeloma Cells Regulates Osteoclast and Osteoblast Activity and Induces Bone Destruction Cancer Research, December 19, 2012

146 Nrf2 expression is associated with poor outcome in osteosarcoma Pathology, December 19, 2012

147 TGF-β1 Signal is Crucial for De-Differentiation of Cancer Cells to Cancer Stem Cells in Osteosarcoma Stem Cells, December 14, 2012

148 Overexpression of CD9 in human breast cancer cells promotes the development of bone metastases Anticancer Research, December 10, 2012

149 Low-grade Central Osteosarcoma of the Metatarsal Bone: A Clinicopathological, Immunohistochemical, Cytogenetic and Molecular Cytogenetic Analysis Anticancer Research, December 10, 2012

150 The US postmarketing surveillance study of adult osteosarcoma and teriparatide: Study design and findings from the first 7 years Journal of Bone and Mineral Research, December 6, 2012 Clinical Article

151 Bone and soft tissue tumors of hip and pelvis European Journal of Radiology, December 6, 2012

152 Identification of circulating microRNAs as diagnostic biomarkers for use in multiple myeloma British Journal of Cancer, November 28, 2012

153 Healthcare utilization and costs associated with skeletal-related events in prostate cancer patients with bone metastases Prostate Cancer & Prostatic Diseases, November 26, 2012

154 Single-fraction radiotherapy versus multifraction radiotherapy for palliation of painful vertebral bone metastases--Equivalent efficacy, less toxicity, more convenient Cancer, November 26, 2012

155 Giant cell tumor of the tendon sheath mimicking a primary intramedullary metatarsal tumor Skeletal Radiology, November 20, 2012

156 Increased expression of CD24 is associated with tumor progression and prognosis in patients suffering osteosarcoma Clinical and Translational Oncology, November 15, 2012

157 Composite Reconstruction of the Hip Following Resection of Periacetabular Tumors: Middle-Term Outcome Journal of Arthroplasty, November 12, 2012

158 Analysis of the efficacy and prognosis of limb-salvage surgery for osteosarcoma around the knee European Journal of Surgical Oncology, November 12, 2012

159 Epiphysis preserving operations for the treatment of lower limb malignant bone tumors European Journal of Surgical Oncology, November 12, 2012

160 Osteosarcomas of the mandible: multidisciplinary management of a rare tumor of the young adult a cooperative study of the GSF-GETO, Rare Cancer Network, GETTEC/REFCOR and SFCE Annals of Oncology, November 8, 2012

50 available pages First Previous 8 9 10 11 12 13 14 15 16 17 Next Last

Clinical Pearls in Oncology

The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 18F-FDG PET SUVmax as an indicator of histopathologic response after neoadjuvant chemotherapy in extremity osteosarcoma European Journal of Nuclear Medicine & Molecular Imaging, April 11, 2013

2 Preoperative and Therapeutic Embolization of Extremities of Bone and Soft Tissue Tumors Angiology, April 11, 2013

3 Pulmonary metastasectomy for osteogenic and soft tissue sarcoma: who really benefits from surgical treatment? European Journal of Cardio-Thoracic Surgery, April 5, 2013 Review Article

4 Incidence and relative survival of chordomas Cancer, April 4, 2013 Review Article

5 Osteosarcoma of the mobile spine Annals of Oncology, April 26, 2013

6 Risk of cancer following primary total hip replacement or primary resurfacing arthroplasty of the hip: a retrospective cohort study in Scotland British Journal of Cancer, April 5, 2013

7 Biological Reconstruction Following the Resection of Malignant Bone Tumors of the Pelvis Sarcoma, April 17, 2013

8 Do Malignant Bone Tumors of the Foot Have a Different Biological Behavior than Sarcomas at Other Skeletal Sites Sarcoma, April 1, 2013

9 The Correlation Between Dose of Folinic Acid and Neurotoxicity in Children and Adolescents Treated for Osteosarcoma With High-dose Methotrexate (HDMTX): A Neuropsychological and Psychosocial Study Journal of Pediatric Hematology/Oncology, April 29, 2013

10 MicroRNA-199b-5p is involved in the Notch signaling pathway in osteosarcoma Human Pathology, April 11, 2013

11 Repiphysis prosthesis for limb preservation in pediatric patients with bone cancer: a literature review Orthopaedic Nursing, April 8, 2013 Review Article

12 Soft Tissue Chordomas: A Clinicopathologic Analysis of 11 Cases American Journal of Surgical Pathology , April 26, 2013

13 Retrospective analysis of antitumor effects of zoledronic acid in breast cancer patients with bone-only metastases Cancer, April 16, 2012 Free full text

14 Giant Cell Tumor of Bone: Review, Mimics, and New Developments in Treatment RadioGraphics, January 21, 2013 Review Article

15 Osseous Myxochondroid Sarcoma: A Detailed Study of 5 Cases of Extraskeletal Myxoid Chondrosarcoma of the Bone American Journal of Surgical Pathology , April 29, 2013

16 Satb2 is a novel marker of osteoblastic differentiation In bone and soft tissue tumors Histopathology, April 4, 2013

17 A systematic review of vascular endothelial growth factor expression as a biomarker of prognosis in patients with osteosarcoma Tumor Biology, April 18, 2013 Review Article

18 A Disintegrin And Metalloproteinase 12 produced by tumour cells accelerates osteosarcoma tumour progression and associated osteolysis European Journal of Cancer, April 29, 2013

19 The Combination of Sorafenib and Everolimus Abrogates mTORC1 and mTORC2 Upregulation in Osteosarcoma Preclinical Models Clinical Cancer Research, April 12, 2013

20 Evaluation of Quercetin as a Potential Drug in Osteosarcoma Treatment Anticancer Research, April 11, 2013

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more

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Oncology - Bone/Cartilage News & Articles

Articles

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

HCC risk increased in patients with AIDS

RAB25 is a prognostic marker for ovarian cancer

Most Popular Oncology Articles

Other Topics in Oncology