Oncology - Bone/Cartilage News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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Articles

Latest Full Text Articles (52) Focus on Neurologic

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

101 Hematopoietic stem cells give rise to osteo-chondrogenic cells Blood Cells, Molecules, and Diseases, February 1, 2013 Clinical Article

102 Alpha-CaMKII plays a critical role in determining the aggressive behavior of human osteosarcoma Molecular Cancer Research, February 1, 2013 Clinical Article

103 Endoscopic endonasal approach for the treatment of a large clival giant cell tumor complicated by an intraoperative internal carotid artery rupture Full Text Cancer Management and Research, January 31, 2013

104 Treatment of Bone Metastases with Microwave Thermal Ablation Journal of Vascular and Interventional Radiology, January 31, 2013 Clinical Article

105 DNA: leukemia's secret weapon of bone mass destruction Oncogene, January 30, 2013 Clinical Article

106 Single fraction conventional external beam radiation therapy for bone metastases: A systematic review of randomised controlled trials Radiotherapy & Oncology, January 30, 2013 Clinical Article

107 Preventing MEK1 activation influences the responses of human osteosarcoma cells to bone morphogenetic proteins 2 and 9 Anti-Cancer Drugs, January 29, 2013

108 Hand-Schüller-Christian Disease and Erdheim-Chester Disease: Coexistence and Discrepancy Full Text The Oncologist, January 29, 2013

109 Bone Sarcomas: From Biology to Targeted Therapies Sarcoma, January 28, 2013 Clinical Article

110 MAPK/ERK Signaling in Osteosarcomas, Ewing Sarcomas and Chondrosarcomas: Therapeutic Implications and Future Directions Sarcoma, January 28, 2013 Review Article

111 RAF265, a dual BRAF and VEGFR2 inhibitor, prevents osteoclast formation and resorption. Therapeutic implications Investigational New Drugs, January 28, 2013 Clinical Article

112 Imaging of primary bone tumors: determination of tumor extent by non-contrast sequences Pediatric Radiology, January 28, 2013 Clinical Article

113 Intronic deletion and duplication proximal of the EXT1 gene: A novel causative mechanism for multiple osteochondromas Genes, Chromosomes and Cancer, January 25, 2013 Clinical Article

114 The Genetics of Osteosarcoma Sarcoma, January 25, 2013 Review Article

115 Integrative molecular and functional profiling of ERBB2-amplified breast cancers identifies new genetic dependencies Oncogene, January 24, 2013 Clinical Article

116 Factors impacting stem cell mobilization failure rate and efficiency in multiple myeloma in the era of novel therapies - experience at Memorial Sloan Kettering Cancer Center Bone Marrow Transplantation, January 24, 2013 Clinical Article

117 Type I mutation in the F11 gene is a third ancestral mutation which causes factor XI deficiency in Ashkenazi Jews Journal of Thrombosis and Haemostasis, January 24, 2013 Clinical Article

118 Association analyses of osteoprotegerin gene polymorphisms with bone mineral density in Chinese postmenopausal women Medical Oncology, January 24, 2013 Clinical Article

119 Assessment of set-up discrepancies using daily portal imaging during radiotherapy treatment for patients with spine and bone metastases Journal of Radiotherapy in Practice, January 24, 2013 Clinical Article

120 Prognostic significance of programmed cell death-1-positive cells in follicular lymphoma patients may alter in the rituximab era European Journal of Haematology, January 22, 2013 Clinical Article

50 available pages First Previous 6 7 8 9 10 11 12 13 14 15 Next Last

Clinical Pearls in Oncology

The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 18F-FDG PET SUVmax as an indicator of histopathologic response after neoadjuvant chemotherapy in extremity osteosarcoma European Journal of Nuclear Medicine & Molecular Imaging, April 11, 2013

2 Preoperative and Therapeutic Embolization of Extremities of Bone and Soft Tissue Tumors Angiology, April 11, 2013

3 Pulmonary metastasectomy for osteogenic and soft tissue sarcoma: who really benefits from surgical treatment? European Journal of Cardio-Thoracic Surgery, April 5, 2013 Review Article

4 Incidence and relative survival of chordomas Cancer, April 4, 2013 Review Article

5 Osteosarcoma of the mobile spine Annals of Oncology, April 26, 2013

6 Risk of cancer following primary total hip replacement or primary resurfacing arthroplasty of the hip: a retrospective cohort study in Scotland British Journal of Cancer, April 5, 2013

7 Biological Reconstruction Following the Resection of Malignant Bone Tumors of the Pelvis Sarcoma, April 17, 2013

8 Do Malignant Bone Tumors of the Foot Have a Different Biological Behavior than Sarcomas at Other Skeletal Sites Sarcoma, April 1, 2013

9 The Correlation Between Dose of Folinic Acid and Neurotoxicity in Children and Adolescents Treated for Osteosarcoma With High-dose Methotrexate (HDMTX): A Neuropsychological and Psychosocial Study Journal of Pediatric Hematology/Oncology, April 29, 2013

10 MicroRNA-199b-5p is involved in the Notch signaling pathway in osteosarcoma Human Pathology, April 11, 2013

11 Repiphysis prosthesis for limb preservation in pediatric patients with bone cancer: a literature review Orthopaedic Nursing, April 8, 2013 Review Article

12 Soft Tissue Chordomas: A Clinicopathologic Analysis of 11 Cases American Journal of Surgical Pathology , April 26, 2013

13 Retrospective analysis of antitumor effects of zoledronic acid in breast cancer patients with bone-only metastases Cancer, April 16, 2012 Free full text

14 Giant Cell Tumor of Bone: Review, Mimics, and New Developments in Treatment RadioGraphics, January 21, 2013 Review Article

15 Osseous Myxochondroid Sarcoma: A Detailed Study of 5 Cases of Extraskeletal Myxoid Chondrosarcoma of the Bone American Journal of Surgical Pathology , April 29, 2013

16 Satb2 is a novel marker of osteoblastic differentiation In bone and soft tissue tumors Histopathology, April 4, 2013

17 A systematic review of vascular endothelial growth factor expression as a biomarker of prognosis in patients with osteosarcoma Tumor Biology, April 18, 2013 Review Article

18 A Disintegrin And Metalloproteinase 12 produced by tumour cells accelerates osteosarcoma tumour progression and associated osteolysis European Journal of Cancer, April 29, 2013

19 The Combination of Sorafenib and Everolimus Abrogates mTORC1 and mTORC2 Upregulation in Osteosarcoma Preclinical Models Clinical Cancer Research, April 12, 2013

20 Evaluation of Quercetin as a Potential Drug in Osteosarcoma Treatment Anticancer Research, April 11, 2013

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more

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Oncology - Bone/Cartilage News & Articles

Articles

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

HCC risk increased in patients with AIDS

RAB25 is a prognostic marker for ovarian cancer

Most Popular Oncology Articles

Other Topics in Oncology