Oncology - Bone/Cartilage News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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D Scott Cunningham MD, PhD
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Articles

Latest Full Text Articles (52) Focus on Bone

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

881 Denosumab in men receiving androgen-deprivation therapy for prostate cancer Full Text New England Journal of Medicine, August 26, 2009 Clinical Article

882 Prediction model of chemotherapy response in osteosarcoma by 18F-FDG PET and MRI The Journal of Nuclear Medicine, August 26, 2009
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883 Disease-specific risk for an osteonecrosis of the jaw under bisphosphonate therapy Journal of Cancer Research & Clinical Oncology, August 26, 2009

884 Tumoral calcium pyrophosphate dihydrate crystal deposition disease: A rare diagnosis by fine-needle aspiration Diagnostic Cytopathology, August 24, 2009

885 Role of fine-needle aspiration cytology in tuberculosis of bone Diagnostic Cytopathology, August 24, 2009

886 Opioid Switching and Burst Ketamine to Improve the Opioid Response in Patients With Movement-related Pain Due to Bone Metastases The Clinical Journal of Pain, August 21, 2009

887 Hypomethylation of the P3 promoter is associated with up-regulation of IGF2 expression in human osteosarcoma Human Pathology, August 19, 2009

888 Muramyl tripeptide (mifamurtide) for the treatment of osteosarcoma Expert Review of Anticancer Therapy, August 17, 2009

889 Antagonism of chemokine receptor CXCR3 inhibits osteosarcoma metastasis to lungs International Journal of Cancer, August 17, 2009

890 Pathogenesis and management of myeloma bone disease Expert Review of Hematology, August 17, 2009

891 Cathepsin G–Mediated Activation of Pro–Matrix Metalloproteinase 9 at the Tumor-Bone Interface Promotes Transforming Growth Factor-beta Signaling and Bone Destruction Molecular Cancer Research, August 14, 2009

892 Dominant role of CD47-thrombospondin-1 interactions in myeloma induced fusion of human dendritic cells: implications for bone disease Full Text Blood, August 12, 2009

893 Translocation (2;13) and other chromosome abnormalities in intraosseous schwannoma of the mandible Cancer Genetics, August 11, 2009

894 DNA SNPs in myeloma: genetic polymorphisms of EPHX1, Gsk3, TNFSF8 and myeloma cell DKK-1 expression linked to bone disease in myeloma Leukemia, August 11, 2009

895 Economic Analysis of Radiation Therapy Oncology Group 97-14: Multiple Versus Single Fraction Radiation Treatment of Patients With Bone Metastases American Journal of Clinical Oncology, August 10, 2009

896 EGFR-dependent and independent activation of Akt/mTOR cascade in bone and soft tissue tumors Modern Pathology, August 5, 2009

897 Kinome Profiling of Chondrosarcoma Reveals Src-Pathway Activity and Dasatinib as Option for Treatment Full Text Cancer Research, August 4, 2009

898 Addition of muramyl tripeptide to chemotherapy for patients with newly diagnosed metastatic osteosarcoma Full Text Cancer, August 3, 2009

899 ADA-deficient SCID is associated with a specific microenvironment and bone phenotype characterized by RANKL/OPG imbalance and osteoblast insufficiency Full Text Blood, July 29, 2009

900 A Caspase-6 and Anti-HER2 Antibody Chimeric Tumor-Targeted Proapoptotic Molecule Decreased Metastasis of Human Osteosarcoma Cancer Investigation, July 29, 2009

50 available pages First Previous 41 42 43 44 45 46 47 48 49 50 Next Last

Clinical Pearls in Oncology

The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 18F-FDG PET SUVmax as an indicator of histopathologic response after neoadjuvant chemotherapy in extremity osteosarcoma European Journal of Nuclear Medicine & Molecular Imaging, April 11, 2013

2 Preoperative and Therapeutic Embolization of Extremities of Bone and Soft Tissue Tumors Angiology, April 11, 2013

3 Pulmonary metastasectomy for osteogenic and soft tissue sarcoma: who really benefits from surgical treatment? European Journal of Cardio-Thoracic Surgery, April 5, 2013 Review Article

4 Incidence and relative survival of chordomas Cancer, April 4, 2013 Review Article

5 Osteosarcoma of the mobile spine Annals of Oncology, April 26, 2013

6 Risk of cancer following primary total hip replacement or primary resurfacing arthroplasty of the hip: a retrospective cohort study in Scotland British Journal of Cancer, April 5, 2013

7 Biological Reconstruction Following the Resection of Malignant Bone Tumors of the Pelvis Sarcoma, April 17, 2013

8 Do Malignant Bone Tumors of the Foot Have a Different Biological Behavior than Sarcomas at Other Skeletal Sites Sarcoma, April 1, 2013

9 The Correlation Between Dose of Folinic Acid and Neurotoxicity in Children and Adolescents Treated for Osteosarcoma With High-dose Methotrexate (HDMTX): A Neuropsychological and Psychosocial Study Journal of Pediatric Hematology/Oncology, April 29, 2013

10 MicroRNA-199b-5p is involved in the Notch signaling pathway in osteosarcoma Human Pathology, April 11, 2013

11 Repiphysis prosthesis for limb preservation in pediatric patients with bone cancer: a literature review Orthopaedic Nursing, April 8, 2013 Review Article

12 Soft Tissue Chordomas: A Clinicopathologic Analysis of 11 Cases American Journal of Surgical Pathology , April 26, 2013

13 Retrospective analysis of antitumor effects of zoledronic acid in breast cancer patients with bone-only metastases Cancer, April 16, 2012 Free full text

14 Giant Cell Tumor of Bone: Review, Mimics, and New Developments in Treatment RadioGraphics, January 21, 2013 Review Article

15 Osseous Myxochondroid Sarcoma: A Detailed Study of 5 Cases of Extraskeletal Myxoid Chondrosarcoma of the Bone American Journal of Surgical Pathology , April 29, 2013

16 Satb2 is a novel marker of osteoblastic differentiation In bone and soft tissue tumors Histopathology, April 4, 2013

17 A systematic review of vascular endothelial growth factor expression as a biomarker of prognosis in patients with osteosarcoma Tumor Biology, April 18, 2013 Review Article

18 A Disintegrin And Metalloproteinase 12 produced by tumour cells accelerates osteosarcoma tumour progression and associated osteolysis European Journal of Cancer, April 29, 2013

19 The Combination of Sorafenib and Everolimus Abrogates mTORC1 and mTORC2 Upregulation in Osteosarcoma Preclinical Models Clinical Cancer Research, April 12, 2013

20 Evaluation of Quercetin as a Potential Drug in Osteosarcoma Treatment Anticancer Research, April 11, 2013

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more

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Oncology - Bone/Cartilage News & Articles

Articles

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

HCC risk increased in patients with AIDS

RAB25 is a prognostic marker for ovarian cancer

Most Popular Oncology Articles

Other Topics in Oncology