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Oncology - Bone/Cartilage News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (2) Full Text Articles (52) Focus on Neurologic
Ranked, sorted, and summarized by MDLinx editors from the latest literature
Topics:

821 A balanced t(5;17) (p15;q22-23) in chondroblastoma: frequency of the re-arrangement and analysis of the candidate genes Full Text BMC Cancer, November 13, 2009

822 Deletion of the WWOX gene and frequent loss of its protein expression in human osteosarcoma Cancer Letters, November 12, 2009

823 Overexpression of A disintegrin and metalloproteinase 28 is correlated with high histologic grade in conventional chondrosarcoma Human Pathology, November 12, 2009

824 Fine-needle aspiration cytology of extraskeletal myxoid chondrosarcoma: A case report Diagnostic Cytopathology, November 11, 2009

825 Reconstruction Using a Frozen Bone Method for Osteosarcoma of the Talus. A Case Report and Review of the Literature Anticancer Research, November 11, 2009

826 Profiling of high-grade central osteosarcoma and its putative progenitor cells identifies tumourigenic pathways British Journal of Cancer, November 6, 2009

827 Endoprosthetic proximal femur replacement: Metastatic versus primary tumors Surgical Oncology, November 5, 2009

828 Honokiol induces cell apoptosis in human chondrosarcoma cells through mitochondrial dysfunction and endoplasmic reticulum stress Cancer Letters, November 5, 2009

829 Giant cell tumor of the extremity: A review of 349 cases from a single institution Cancer Treatment Reviews, November 5, 2009

830 Inactive Wnt/beta-catenin pathway in conventional high-grade osteosarcoma The Journal of Pathology, November 5, 2009

831 Bone and [ 18 F]Fluorodeoxyglucose positron-emission tomography/computed tomography scanning for the assessment of osseous involvement in Hodgkin lymphoma in children and young adults Leukemia and Lymphoma, November 4, 2009

832 Cell cycle inhibition and apoptosis induced by curcumin in Ewing sarcoma cell line SK-NEP-1 Medical Oncology, November 4, 2009

833 Frequent deletion of CDKN2A and recurrent coamplification of KIT, PDGFRA, and KDR in fibrosarcoma of bone - An array comparative genomic hybridization study Genes, Chromosomes and Cancer, November 2, 2009

834 Multidisciplinary treatment including sorafenib stabilized the bone metastases of renal cell carcinoma in an immunosuppressed renal transplant recipient International Journal of Clinical Oncology, October 30, 2009

835 Oncogenous osteomalacia Full Text Journal of Cancer Research and Therapeutics, October 28, 2009

836 Metastatic potential of an aneurysmal bone cyst Virchows Archiv, October 27, 2009

837 Interventions for central giant cell granuloma (CGCG) of the jaws Cochrane Reviews, October 27, 2009

838 Histological heterogeneity of Ewings sarcoma/PNET: an immunohistochemical analysis of 415 genetically confirmed cases with clinical support Virchows Archiv, October 27, 2009

839 Primary Ewing's sarcoma of the frontal bone with intracranial extension Full Text Journal of Cancer Research and Therapeutics, October 27, 2009

840 Synchronous and metachronous skeletal osteosarcomas: The Norwegian Radium Hospital experience Acta Oncologica, October 26, 2009

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Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 18F-FDG PET SUVmax as an indicator of histopathologic response after neoadjuvant chemotherapy in extremity osteosarcoma European Journal of Nuclear Medicine & Molecular Imaging, April 11, 2013

2 Preoperative and Therapeutic Embolization of Extremities of Bone and Soft Tissue Tumors Angiology, April 11, 2013

3 Pulmonary metastasectomy for osteogenic and soft tissue sarcoma: who really benefits from surgical treatment? European Journal of Cardio-Thoracic Surgery, April 5, 2013    Review Article

4 Incidence and relative survival of chordomas Cancer, April 4, 2013    Review Article

5 Osteosarcoma of the mobile spine Annals of Oncology, April 26, 2013

6 Risk of cancer following primary total hip replacement or primary resurfacing arthroplasty of the hip: a retrospective cohort study in Scotland British Journal of Cancer, April 5, 2013

7 Biological Reconstruction Following the Resection of Malignant Bone Tumors of the Pelvis Sarcoma, April 17, 2013

8 Do Malignant Bone Tumors of the Foot Have a Different Biological Behavior than Sarcomas at Other Skeletal Sites Sarcoma, April 1, 2013

9 The Correlation Between Dose of Folinic Acid and Neurotoxicity in Children and Adolescents Treated for Osteosarcoma With High-dose Methotrexate (HDMTX): A Neuropsychological and Psychosocial Study Journal of Pediatric Hematology/Oncology, April 29, 2013

10 MicroRNA-199b-5p is involved in the Notch signaling pathway in osteosarcoma Human Pathology, April 11, 2013

11 Repiphysis prosthesis for limb preservation in pediatric patients with bone cancer: a literature review Orthopaedic Nursing, April 8, 2013    Review Article

12 Soft Tissue Chordomas: A Clinicopathologic Analysis of 11 Cases American Journal of Surgical Pathology , April 26, 2013

13 Retrospective analysis of antitumor effects of zoledronic acid in breast cancer patients with bone-only metastases Cancer, April 16, 2012    Free full text

14 Giant Cell Tumor of Bone: Review, Mimics, and New Developments in Treatment RadioGraphics, January 21, 2013    Review Article

15 Osseous Myxochondroid Sarcoma: A Detailed Study of 5 Cases of Extraskeletal Myxoid Chondrosarcoma of the Bone American Journal of Surgical Pathology , April 29, 2013

16 Satb2 is a novel marker of osteoblastic differentiation In bone and soft tissue tumors Histopathology, April 4, 2013

17 A systematic review of vascular endothelial growth factor expression as a biomarker of prognosis in patients with osteosarcoma Tumor Biology, April 18, 2013    Review Article

18 A Disintegrin And Metalloproteinase 12 produced by tumour cells accelerates osteosarcoma tumour progression and associated osteolysis European Journal of Cancer, April 29, 2013

19 The Combination of Sorafenib and Everolimus Abrogates mTORC1 and mTORC2 Upregulation in Osteosarcoma Preclinical Models Clinical Cancer Research, April 12, 2013

20 Evaluation of Quercetin as a Potential Drug in Osteosarcoma Treatment Anticancer Research, April 11, 2013

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncologymore

Other Topics in Oncology

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