Oncology - Bone/Cartilage News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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Articles

Latest (3) Full Text Articles (52) Focus on Liver

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

641 Hypoxia and hypoglycaemia in Ewing's sarcoma and osteosarcoma: regulation and phenotypic effects of Hypoxia-Inducible Factor Full Text BMC Cancer, July 30, 2010

642 Serum follistatin in patients with prostate cancer metastatic to the bone Clinical and Experimental Metastasis, July 29, 2010

643 Intercohort Gene Expression Co-Analysis Reveals Chemokine Receptors as Prognostic Indicators in Ewing's Sarcoma Full Text Clinical Cancer Research, July 28, 2010

644 Differential gene expression in classic giant cell tumours of bone: Tenascin C as biological risk factor for local relapses and metastases Histopathology, July 28, 2010

645 Inflammatory myofibroblastic tumor of bone: two cases occurring in long bone Skeletal Radiology, July 26, 2010

646 Bisphosphonates Induce Apoptosis of Circulating Endothelial Cells in Multiple Myeloma Patients and in Subjects with Bisphosphonate-Induced Osteonecrosis of the Jaws Acta Haematologica, July 23, 2010

647 Symptomatic vertebral hemangioma: Treatment with radiotherapy Journal of Cancer Research and Therapeutics, July 23, 2010

648 Genomic Alterations and Allelic Imbalances are Strong Prognostic Predictors in Osteosarcoma Full Text Clinical Cancer Research, July 22, 2010

649 N-telopeptide of type I collagen is useful for monitoring therapeutic response in non-small cell lung cancer patients with bone metastases International Journal of Clinical Oncology, July 22, 2010

650 The epidemiology of bone cancer in 0-39 year olds in northern England, 1981-2002 Full Text BMC Cancer, July 21, 2010

651 Immunohistochemical analysis of MDM2 and CDK4 distinguishes low-grade osteosarcoma from benign mimics Modern Pathology, July 20, 2010

652 Prognostic impact of adenomatous polyposis coli gene expression in osteosarcoma of the extremities European Journal of Cancer, July 16, 2010

653 Inhaled GM-CSF for First Pulmonary Recurrence of Osteosarcoma; Effects on Disease Free Survival and Immunomodulation: A Report from The Children's Oncology Group Full Text Clinical Cancer Research, July 14, 2010

654 Prognostic factors for skeletal complications from metastatic bone disease in breast cancer Breast Cancer Research and Treatment, July 14, 2010

655 Evidence for the role of matrix metalloproteinase-13 in bone resorption by giant cell tumor of bone Human Pathology, July 13, 2010

656 Understanding Micrometastatic Disease and Anoikis Resistance in Ewing Family of Tumors and Osteosarcoma Full Text The Oncologist, July 13, 2010

657 Ectopic primary type A thymoma located in two thoracic vertebras: a case report Full Text BMC Cancer, July 13, 2010

658 Phage Display Derived Peptides for Osteosarcoma Imaging Full Text Clinical Cancer Research, July 9, 2010

659 Expression of vascular endothelial growth factor and matrix metalloproteinase-9 in sacral chordoma Journal of Neuro-Oncology, July 8, 2010

660 Osteosarcoma is characterised by reduced expression of markers of osteoclastogenesis and antigen presentation compared with normal bone British Journal of Cancer, July 6, 2010

50 available pages First Previous 33 34 35 36 37 38 39 40 41 42 Next Last

Clinical Pearls in Oncology

The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 18F-FDG PET SUVmax as an indicator of histopathologic response after neoadjuvant chemotherapy in extremity osteosarcoma European Journal of Nuclear Medicine & Molecular Imaging, April 11, 2013

2 Preoperative and Therapeutic Embolization of Extremities of Bone and Soft Tissue Tumors Angiology, April 11, 2013

3 Pulmonary metastasectomy for osteogenic and soft tissue sarcoma: who really benefits from surgical treatment? European Journal of Cardio-Thoracic Surgery, April 5, 2013 Review Article

4 Incidence and relative survival of chordomas Cancer, April 4, 2013 Review Article

5 Osteosarcoma of the mobile spine Annals of Oncology, April 26, 2013

6 Risk of cancer following primary total hip replacement or primary resurfacing arthroplasty of the hip: a retrospective cohort study in Scotland British Journal of Cancer, April 5, 2013

7 Biological Reconstruction Following the Resection of Malignant Bone Tumors of the Pelvis Sarcoma, April 17, 2013

8 Do Malignant Bone Tumors of the Foot Have a Different Biological Behavior than Sarcomas at Other Skeletal Sites Sarcoma, April 1, 2013

9 The Correlation Between Dose of Folinic Acid and Neurotoxicity in Children and Adolescents Treated for Osteosarcoma With High-dose Methotrexate (HDMTX): A Neuropsychological and Psychosocial Study Journal of Pediatric Hematology/Oncology, April 29, 2013

10 MicroRNA-199b-5p is involved in the Notch signaling pathway in osteosarcoma Human Pathology, April 11, 2013

11 Repiphysis prosthesis for limb preservation in pediatric patients with bone cancer: a literature review Orthopaedic Nursing, April 8, 2013 Review Article

12 Soft Tissue Chordomas: A Clinicopathologic Analysis of 11 Cases American Journal of Surgical Pathology , April 26, 2013

13 Retrospective analysis of antitumor effects of zoledronic acid in breast cancer patients with bone-only metastases Cancer, April 16, 2012 Free full text

14 Giant Cell Tumor of Bone: Review, Mimics, and New Developments in Treatment RadioGraphics, January 21, 2013 Review Article

15 Osseous Myxochondroid Sarcoma: A Detailed Study of 5 Cases of Extraskeletal Myxoid Chondrosarcoma of the Bone American Journal of Surgical Pathology , April 29, 2013

16 Satb2 is a novel marker of osteoblastic differentiation In bone and soft tissue tumors Histopathology, April 4, 2013

17 A systematic review of vascular endothelial growth factor expression as a biomarker of prognosis in patients with osteosarcoma Tumor Biology, April 18, 2013 Review Article

18 A Disintegrin And Metalloproteinase 12 produced by tumour cells accelerates osteosarcoma tumour progression and associated osteolysis European Journal of Cancer, April 29, 2013

19 The Combination of Sorafenib and Everolimus Abrogates mTORC1 and mTORC2 Upregulation in Osteosarcoma Preclinical Models Clinical Cancer Research, April 12, 2013

20 Evaluation of Quercetin as a Potential Drug in Osteosarcoma Treatment Anticancer Research, April 11, 2013

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more

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Oncology - Bone/Cartilage News & Articles

Articles

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

HCC risk increased in patients with AIDS

RAB25 is a prognostic marker for ovarian cancer

Most Popular Oncology Articles

Other Topics in Oncology