Oncology - Bone/Cartilage News & Articles

Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.

On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.

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D Scott Cunningham MD, PhD
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Articles

Latest (3) Full Text Articles (52) Focus on Liver

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

421 Chemotherapeutic adjuvant treatment for osteosarcoma: Where do we stand European Journal of Cancer, June 29, 2011 Evidence Based Medicine Clinical Article

422 Targeting myeloma-osteoclast interaction with V gamma 9Vδ2 T cells International Journal of Hematology, June 28, 2011

423 TAK1-TAB2 signaling contributes to bone destruction by breast carcinoma cells Molecular Cancer Research, June 27, 2011

424 Quantitative Sensory Testing to assess the sensory characteristics of cancer-induced bone pain after radiotherapy and potential clinical biomarkers of response European Journal of Pain, June 21, 2011 Clinical Article

425 Intercalary Segmental Reconstruction of Long Bones After Malignant Bone Tumor Resection Using Primary Methyl Methacrylate Cement Spacer Interposition and Secondary Bone Grafting: The Induced Membrane Technique Journal of Pediatric Orthopaedics , June 21, 2011

426 Calpain-6 is an endothelin-1 signaling dependent protective factor in chemoresistant osteosarcoma International Journal of Cancer, June 21, 2011

427 Primary bone lymphoma: a clinicopathological retrospective study of 28 patients in a single institution Journal of Research in Medical Sciences, June 20, 2011

428 New developments for treatment and prevention of bone metastases Current Opinion in Oncology, June 14, 2011 Clinical Article

429 Highlights from ASCO 2011-Denosumab versus zoledronic acid in patients with bone metastases from solid tumors other than breast and prostate cancers or multiple myeloma: A number needed to treat (NNT) analysis Clinical Impact, from MDLinx , June 8, 2011

430 Giant cell tumour of tendon sheath of the digits. A systematic review HAND, June 8, 2011 Evidence Based Medicine

431 Long-term risks of subsequent primary neoplasms among survivors of childhood cancer JAMA, June 7, 2011

432 Glucocorticoid Receptor {alpha} Isoform-Selective Regulation of Antiapoptotic Genes in Osteosarcoma Cells: A New Mechanism for Glucocorticoid Resistance Full Text Molecular Endocrinology, June 2, 2011

433 Tandem chemo-mobilization followed by high-dose melphalan and carmustine with single autologous hematopoietic cell transplantation for multiple myeloma Bone Marrow Transplantation, June 2, 2011

434 The immunophenotype of osteoclasts and macrophage polykaryons Journal of Clinical Pathology, May 25, 2011

435 Osteoclast formation and function in, pigmented villonodular synovitis The Journal of Pathology, May 24, 2011

436 PROX1 is a predictor of survival for gliomas WHO grade II British Journal of Cancer, May 16, 2011

437 Circulating osteopontin: a dual marker of bone destruction and angiogenesis in patients with multiple myeloma. Journal of Hematology & Oncology, May 12, 2011

438 Quantifying sclerotic bone metastases with 2D ultra short TE MRI: A feasibility study Cancer Biomarkers, May 12, 2011

439 Cementoplasty for painful bone metastases: a series of 42 cases Medical Oncology, May 11, 2011

440 Involvement of Cancer Biomarker C7orf24 in the Growth of Human Osteosarcoma Anticancer Research, May 10, 2011

50 available pages First Previous 22 23 24 25 26 27 28 29 30 31 Next Last

Clinical Pearls in Oncology

The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.

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HCC risk increased in patients with AIDS

As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.

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RAB25 is a prognostic marker for ovarian cancer

As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.

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Most Popular Oncology Articles

Last month's top read Top Articles of 2012

1 18F-FDG PET SUVmax as an indicator of histopathologic response after neoadjuvant chemotherapy in extremity osteosarcoma European Journal of Nuclear Medicine & Molecular Imaging, April 11, 2013

2 Preoperative and Therapeutic Embolization of Extremities of Bone and Soft Tissue Tumors Angiology, April 11, 2013

3 Pulmonary metastasectomy for osteogenic and soft tissue sarcoma: who really benefits from surgical treatment? European Journal of Cardio-Thoracic Surgery, April 5, 2013 Review Article

4 Incidence and relative survival of chordomas Cancer, April 4, 2013 Review Article

5 Osteosarcoma of the mobile spine Annals of Oncology, April 26, 2013

6 Risk of cancer following primary total hip replacement or primary resurfacing arthroplasty of the hip: a retrospective cohort study in Scotland British Journal of Cancer, April 5, 2013

7 Biological Reconstruction Following the Resection of Malignant Bone Tumors of the Pelvis Sarcoma, April 17, 2013

8 Do Malignant Bone Tumors of the Foot Have a Different Biological Behavior than Sarcomas at Other Skeletal Sites Sarcoma, April 1, 2013

9 The Correlation Between Dose of Folinic Acid and Neurotoxicity in Children and Adolescents Treated for Osteosarcoma With High-dose Methotrexate (HDMTX): A Neuropsychological and Psychosocial Study Journal of Pediatric Hematology/Oncology, April 29, 2013

10 MicroRNA-199b-5p is involved in the Notch signaling pathway in osteosarcoma Human Pathology, April 11, 2013

11 Repiphysis prosthesis for limb preservation in pediatric patients with bone cancer: a literature review Orthopaedic Nursing, April 8, 2013 Review Article

12 Soft Tissue Chordomas: A Clinicopathologic Analysis of 11 Cases American Journal of Surgical Pathology , April 26, 2013

13 Retrospective analysis of antitumor effects of zoledronic acid in breast cancer patients with bone-only metastases Cancer, April 16, 2012 Free full text

14 Giant Cell Tumor of Bone: Review, Mimics, and New Developments in Treatment RadioGraphics, January 21, 2013 Review Article

15 Osseous Myxochondroid Sarcoma: A Detailed Study of 5 Cases of Extraskeletal Myxoid Chondrosarcoma of the Bone American Journal of Surgical Pathology , April 29, 2013

16 Satb2 is a novel marker of osteoblastic differentiation In bone and soft tissue tumors Histopathology, April 4, 2013

17 A systematic review of vascular endothelial growth factor expression as a biomarker of prognosis in patients with osteosarcoma Tumor Biology, April 18, 2013 Review Article

18 A Disintegrin And Metalloproteinase 12 produced by tumour cells accelerates osteosarcoma tumour progression and associated osteolysis European Journal of Cancer, April 29, 2013

19 The Combination of Sorafenib and Everolimus Abrogates mTORC1 and mTORC2 Upregulation in Osteosarcoma Preclinical Models Clinical Cancer Research, April 12, 2013

20 Evaluation of Quercetin as a Potential Drug in Osteosarcoma Treatment Anticancer Research, April 11, 2013

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more

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Oncology - Bone/Cartilage News & Articles

Articles

Clinical Pearls in Oncology

Highlights in Oncology

VEGFR-1 is a prognostic marker for HCC

HCC risk increased in patients with AIDS

RAB25 is a prognostic marker for ovarian cancer

Most Popular Oncology Articles

Other Topics in Oncology