Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
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21 Determination of the apoptotic index in osteosarcoma tissue and its relationship with patients prognosis Cancer Cell International, June 6, 2013 Clinical Article
22 Activating transcription factor 4, an ER stress mediator, is required for, but excessive ER stress suppresses osteoblastogenesis by bortezomib International Journal of Hematology, June 6, 2013 Clinical Article
23 Reverse sural rotational flap in the coverage of the lower leg after musculoskeletal oncologic resection European Journal of Plastic Surgery, June 5, 2013
24 Usefulness of bone turnover markers as predictors of mortality risk, disease progression and skeletal-related events appearance in patients with prostate cancer with bone metastases following treatment with zoledronic acid: TUGAMO study British Journal of Cancer, June 4, 2013 Clinical Article
25 Efficacy of bevacizumab-containing chemotherapy for non-squamous non-small cell lung cancer with bone metastases Cancer Chemotherapy and Pharmacology, June 4, 2013 Clinical Article
26 Minimal clinically important differences in the brief pain inventory in patients with bone metastases Supportive Care in Cancer, June 4, 2013 Clinical Article
27 Pre- and postoperative lower extremity motor power and ambulatory status of patients with spinal cord compression due to a metastatic spinal tumor Spine, June 4, 2013 Review Article
28 Efficacy and safety of 12-weekly versus 4-weekly zoledronic acid for prolonged treatment of patients with bone metastases from breast cancer (ZOOM): a phase 3, open-label, randomised, non-inferiority trial The Lancet Oncology, June 3, 2013 Clinical Article
29 Dual pathology proximal median nerve compression of the forearm Journal of Plastic, Reconstructive & Aesthetic Surgery, May 31, 2013
30 Castlemans disease in the retroperitoneal space mimicking a paraspinal schwannoma: a case report Full Text World Journal of Surgical Oncology, May 30, 2013
31 Reduced intensity-conditioned allogeneic stem cell transplantation for multiple myeloma relapsing or progressing after autologous transplantation: a study by the European Group for Blood and Marrow Transplantation Bone Marrow Transplantation, May 29, 2013 Review Article
32 Smad3 is the key to transforming growth factor-β1-induced osteoclast differentiation in giant cell tumor of bone Medical Oncology, May 28, 2013 Clinical Article
33 CXCR4-targeted therapy inhibits VEGF expression and chondrosarcoma angiogenesis and metastasis Molecular Cancer Therapeutics, May 28, 2013 Clinical Article
34 The use of free microvascular techniques to improve the results of van nes rotationplasty Annals of Plastic Surgery, May 28, 2013 Clinical Article
35 Survival analysis of patients with chondrosarcomas of the pelvis Journal of Surgical Oncology, May 23, 2013 Clinical Article
36 IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma Full Text BMC Cancer, May 22, 2013 Clinical Article
37 Osteosarcoma of the jaw: An analysis of a series of 74 cases Histopathology, May 21, 2013 Clinical Article
38 Synergistic relationship between dipeptidyl peptidase IV and neutral endopeptidase expression and the combined prognostic significance in osteosarcoma patients Medical Oncology, May 21, 2013 Clinical Article
39 Efficacy and safety of 12-weekly versus 4-weekly zoledronic acid for prolonged treatment of patients with bone metastases from breast cancer (ZOOM): a phase 3, open-label, randomised, non-inferiority trial The Lancet Oncology, May 17, 2013 Clinical Article
40 Benefits and adverse events in younger versus older patients receiving neoadjuvant chemotherapy for osteosarcoma: findings from a meta-analysis Journal of Clinical Oncology, May 17, 2013 Review Article
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summary1 Chemotherapy in pediatric bone and soft-tissue sarcomas Current Orthopaedic Practice , May 15, 2013 Review Article
2 Feasibility and dose discovery analysis of zoledronic acid with concurrent chemotherapy in the treatment of newly diagnosed metastatic osteosarcoma European Journal of Cancer, May 13, 2013
3 IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma BMC Cancer, May 22, 2013 Free full text
4 The Cancer Stem Cell Marker CD44 Promotes Bone Metastases by Enhancing Tumorigenicity, Cell Motility, and Hyaluronan Production Cancer Research, May 3, 2013
5 RANKL Synthesized by Both Stromal Cells and Cancer Cells Plays a Crucial Role in Osteoclastic Bone Resorption Induced by Oral Cancer American Journal of Pathology, May 10, 2013
6 Comparing cost-effectiveness analyses of denosumab versus zoledronic acid for the treatment of bone metastases Supportive Care in Cancer, May 6, 2013
7 Efficacy and safety of 12-weekly versus 4-weekly zoledronic acid for prolonged treatment of patients with bone metastases from breast cancer (ZOOM): a phase 3, open-label, randomised, non-inferiority trial The Lancet Oncology, May 17, 2013
8 CD99 suppresses osteosarcoma cell migration through inhibition of ROCK2 activity Oncogene, May 8, 2013
9 Costal osteochondroma spicule associated with pleural effusion Pediatric Surgery International, May 14, 2013
10 Preoperative and Therapeutic Embolization of Extremities of Bone and Soft Tissue Tumors Angiology, April 11, 2013
11 CXCR4-targeted therapy inhibits VEGF expression and chondrosarcoma angiogenesis and metastasis Molecular Cancer Therapeutics, May 28, 2013
12 Survival analysis of patients with chondrosarcomas of the pelvis Journal of Surgical Oncology, May 23, 2013
13 The effect of individualized exercise interventions during treatment in pediatric patients with a malignant bone tumor Supportive Care in Cancer, May 6, 2013
14 Synergistic relationship between dipeptidyl peptidase IV and neutral endopeptidase expression and the combined prognostic significance in osteosarcoma patients Medical Oncology, May 21, 2013
15 Complete Necrosis of a Giant Cell Tumor with High Expression of PPARγ: A Case Report Anticancer Research, May 14, 2013
16 99mTc-MDP- and 18F-FDG-Avid Florid Reactive Periostitis Ossificans Mimicking Recurrent Osteosarcoma Clinical Nuclear Medicine , May 13, 2013
17 Incidence and relative survival of chordomas Cancer, April 4, 2013 Review Article
18 Osteosarcoma of the jaw: An analysis of a series of 74 cases Histopathology, May 21, 2013
19 The Correlation Between Dose of Folinic Acid and Neurotoxicity in Children and Adolescents Treated for Osteosarcoma With High-dose Methotrexate (HDMTX): A Neuropsychological and Psychosocial Study Journal of Pediatric Hematology/Oncology, May 6, 2013
20 Minnelide reduces tumor burden in preclinical models of osteosarcoma Cancer Letters, May 1, 2013
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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