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Oncology - Bone/Cartilage News & Articles
Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Oncology
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Articles
Latest Full Text Articles (52) Focus on Neurologic321 Occipitocervical Reconstruction Through Direct Lateral and Posterior Approach for the Treatment of Primary Osteosarcoma in the Atlas: A Case Report Spine, January 11, 2012
322 Prognostic Value of Tc-99m-MIBI Performed During Middle Course of Preoperative Chemotherapy in Patients With Malignant Bone and Soft-Tissue Tumors Clinical Nuclear Medicine , January 10, 2012
323 Gemcitabine With or Without Docetaxel and Resection for Recurrent Osteosarcoma Journal of Pediatric Hematology/Oncology, January 9, 2012 Clinical Article
324 Tanshinone IIA induces apoptosis and inhibits the proliferation, migration, and invasion of the osteosarcoma MG-63 cell line in vitro Anti-Cancer Drugs, January 4, 2012
325 Spinal cord tumor versus transverse myelitis The Spine Journal, January 4, 2012
326 Extraskeletal Osteosarcoma: Spectrum of Imaging Findings American Journal of Roentgenology, December 30, 2011
327 Predictors of bony morbidity in children with acute lymphoblastic leukemia Pediatric Blood & Cancer, December 28, 2011
328 Length of Symptoms Before Referral: Prognostic Variable for High-grade Soft Tissue Sarcoma Clinical Orthopedics and Related Research, December 22, 2011
329 Immunotherapy targeting HER2 with genetically modified T cells eliminates tumor-initiating cells in osteosarcoma Cancer Gene Therapy, December 21, 2011
330 Dynamic contrast-enhanced magnetic resonance imaging as a prognostic factor in predicting event-free and overall survival in pediatric patients with osteosarcoma Cancer, December 20, 2011
331 Predicting survival in women with breast cancer and brain metastasis Cancer, December 20, 2011
332 Prognostic factors for patients with solitary bone metastasis International Journal of Clinical Oncology, December 20, 2011
333 Strong expression of CXCL12 is associated with a favorable outcome in osteosarcoma Modern Pathology, December 19, 2011
334 The contrasting age-incidence patterns of bone tumours in teenagers and young adults International Journal of Cancer, December 16, 2011
335 MAPK7 and MAP2K4 as prognostic markers in osteosarcoma Human Pathology, December 14, 2011
336 Case of Juxta-Articular Osteoid Osteoma of Calcaneus Mimicking Arthritis The Journal of Foot & Ankle Surgery, December 13, 2011
337 High Long-term Local Control with Sacrectomy for Primary High-grade Bone Sarcoma in Children Full Text Clinical Orthopedics and Related Research, December 12, 2011
338 Osteosarcoma: A rare cause of painful enlargement of the hallux The Foot, December 9, 2011
339 153Samarium-EDTMP administration followed by hematopoietic stem cell support for bone metastases in osteosarcoma patients Full Text Annals of Oncology, December 1, 2011
340 Removal of Osteoid Osteoma of the Tibia Using Two-portal Posterior Ankle Arthroscopy The Journal of Foot & Ankle Surgery, November 23, 2011
Clinical Pearls in Oncology
- The ZORO study demonstrated that the addition of goserelin to neoadjuvant chemotherapy for early breast cancer in premenopausal women resulted in no change in post-chemotherapy rates of amenorrhea
- A little over 50% of tumors in women with ER-positive, node-negative breast cancers will have a RS <18, and current data suggests that these women are UNLIKELY to receive a benefit from adjuvant chemotherapy
- In patients with completely resected ER-positive DCIS when the surgical specimen also has LCIS, consider breast MRI screening in addition to mammography due to the lower sensitivity of mammograms for lobular disease
Highlights in Oncology
VEGFR-1 is a prognostic marker for HCC
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryHCC risk increased in patients with AIDS
As reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryRAB25 is a prognostic marker for ovarian cancer
As reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summaryMost Popular Oncology Articles
Last month's top read Top Articles of 2012Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
Other Topics in Oncology
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