Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
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1 Splenectomy versus conservative management for acute sequestration crises in people with sickle cell disease Cochrane Reviews, June 20, 2013 Evidence Based Medicine
2 An optimized fluorogenic ADAMTS13 assay with increased sensitivity for the investigation of patients with thrombotic thrombocytopenic purpura Journal of Thrombosis and Haemostasis, June 19, 2013 Clinical Article
3 Pre-operative anaemia in colon cancer patients became normal after more than a year post-operatively but did not influence oncological outcome in the final analysis Scandinavian Journal of Gastroenterology, June 19, 2013 Clinical Article
4 A multicenter, randomized, active-controlled study to investigate the efficacy and safety of intravenous ferric carboxymaltose in patients with iron deficiency anemia Transfusion, June 19, 2013
5 Evaluating the prognostic significance of preoperative thrombocytosis in epithelial ovarian cancer Gynecologic Oncology, June 18, 2013 Clinical Article
6 Polymorphisms in the F8 gene and MHC-II variants as risk factors for the development of inhibitory anti-factor VIII antibodies during the treatment of hemophilia A: A computational assessment Full Text PLoS Neglected Tropical Diseases, June 18, 2013
7 The impact of anemia in moderate to severe traumatic brain injury European Journal of Trauma and Emergency Surgery, June 18, 2013 Review Article
8 Incidence and predictors of severe anemia in Asian HIV-infected children using first-line antiretroviral therapy International Journal of Infectious Diseases, June 17, 2013 Clinical Article
9 Postoperative hemolytic uremic syndrome with renal cortical necrosis following laparoscopic hemicolectomy Renal Failure, June 17, 2013
10 Iron deficiency anemia in heart failure Heart Failure Reviews, June 17, 2013 Review Article
11 A phase II study of vorinostat (MK-0683) in patients with polycythaemia vera and essential thrombocythaemia British Journal of Haematology, June 14, 2013 Clinical Article
12 Peginesatide as a new approach for treating anemia of CKD patient: is it like a falling star? Expert Opinion on Pharmacotherapy, June 14, 2013 Review Article
13 Thrombocytopenia in neonates: causes and outcomes Annals of Hematology, June 13, 2013 Clinical Article
14 ATR-Dependent Phosphorylation of FANCM at Serine 1045 is Essential for FANCM Functions Cancer Research, June 12, 2013 Clinical Article
15 Genetic regulation of fetal haemoglobin in inherited bone marrow failure syndromes British Journal of Haematology, June 12, 2013 Clinical Article
16 Blood conservation devices in critical care: a narrative review Full Text Annals of Intensive Care, June 12, 2013 Review Article
17 Iron deficiency anemia in patients with inflammatory bowel disease Full Text Clinical and Experimental Gastroenterology, June 12, 2013 Clinical Article
18 The impact of post-transplant hemoglobin level on renal allograft outcome Transplantation Proceedings, June 11, 2013 Review Article
19 Allogeneic stem cell transplantation for children with acquired severe aplastic anaemia: a retrospective study by the Viva-Asia Blood and Marrow Transplantation Group British Journal of Haematology, June 10, 2013 Clinical Article
20 Low expression of glucocorticoid receptor alpha isoform in adult immune thrombocytopenia correlates with glucocorticoid resistance Annals of Hematology, June 10, 2013 Clinical Article
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summaryIndexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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