Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Oncology
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D Scott Cunningham MD, PhD
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1 Maternal Complications and The Association with Baseline Variables in Pregnant Women with Sickle Cell Disease Hemoglobin, May 20, 2013 Review Article
2 Hepatitis C in patients with β-thalassemia major. A single-centre experience Annals of Hematology, May 17, 2013 Clinical Article
3 Pathogenesis and management of inherited thrombocytopenias: rationale for the use of thrombopoietin-receptor agonists International Journal of Hematology, May 17, 2013 Clinical Article
4 Age, JAK2V617F and SF3B1 mutations are the main predicting factors for survival in refractory anaemia with ring sideroblasts and marked thrombocytosis Leukemia, May 16, 2013 Clinical Article
5 Prevalence and incidence of anemia in the German Heinz Nixdorf Recall Study Annals of Hematology, May 16, 2013 Review Article
6 Iron-deficiency anaemia, gastric hyperplasia, and elevated gastrin levels due to potassium channel dysfunction in the Jervell and Lange-Nielsen Syndrome Cardiology in the Young, May 16, 2013 Clinical Article
7 Ocular manifestations and visual functions in patients with Fanconi anaemia Acta Ophthalmologica, May 16, 2013 Review Article
8 Performance of a clinical prediction score for thrombotic thrombocytopenic purpura in an independent cohort Vox Sanguinis, May 15, 2013 Clinical Article
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Association of anemia and renal function test among diabetes mellitus patients attending Fenote Selam Hospital, West Gojam, Northwest Ethiopia: a cross sectional study Full Text
BMC Hematology, May 15, 2013
Clinical Article
Exclusive Author Commentary
10 Anaemia and cognitive performances in the elderly: a systematic review European Journal of Neurology, May 14, 2013 Evidence Based Medicine Review Article
11 Sensitivity of assays for the detection of HPA-1a antibodies: results of an international workshop demonstrating the impact of cation chelation from integrin αIIbβ3 on three widely used assays Vox Sanguinis, May 14, 2013 Clinical Article
12 Interpreting elevated fetal hemoglobin in pathology and health at the basic laboratory level: new and known - gene mutations associated with hereditary persistence of fetal hemoglobin International Journal of Laboratory Hematology, May 14, 2013 Review Article
13 Using HitAlert flow cytometry to detect heparin-induced thrombocytopenia antibodies in a tertiary care hospital Blood Coagulation & Fibrinolysis, May 14, 2013 Clinical Article
14 Aquagenic pruritus in polycythemia vera: Characteristics and influence on quality of life in 441 patients American Journal of Hematology, May 13, 2013 Clinical Article
15 Hemolytic Anemia After Placement of an Intraluminal Pulmonary Artery Band Annals of Thoracic Surgery, May 13, 2013
16 Population pharmacokinetics of ciclosporin in Chinese children with aplastic anemia: effects of weight, renal function and stanozolol administration Acta Pharmacologica Sinica, May 13, 2013 Clinical Article
17 Travel behaviour of patients with haemophilia Travel Medicine and Infectious Disease , May 13, 2013 Review Article
18 Prognostic value of telomere attrition in patients with aplastic anemia International Journal of Hematology, May 13, 2013 Review Article
19 Treatment of Iron Deficiency Anemia in Children: A Comparative Study of Ferrous Ascorbate and Colloidal Iron The Indian Journal of Pediatrics, May 13, 2013 Review Article
20 Evaluation of ICSH schistocyte measurement guidelines in France International Journal of Laboratory Hematology, May 10, 2013 Clinical Guideline
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summary1 Management of Newly Diagnosed Symptomatic Multiple Myeloma: Updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) Consensus Guidelines 2013 Mayo Clinic Proceedings, April 2, 2013 Clinical Guideline
2 High-dose cyclophosphamide compared with antithymocyte globulin for treatment of acquired severe aplastic anemia Experimental Hematology, April 12, 2013
3 Cytoreduction plus low-dose aspirin versus cytoreduction alone as primary prophylaxis of thrombosis in patients with high-risk essential thrombocythaemia: an observational study British Journal of Haematology, April 15, 2013
4 Low Serum Lipocalin Levels in Patients With Iron Deficiency Anemia Journal of Pediatric Hematology/Oncology, April 1, 2013
5 Intravenous ferric carboxymaltose versus standard medical care in the treatment of iron deficiency anemia in patients with chronic kidney disease: a randomized, active-controlled, multi-center study Nephrology Dialysis Transplantation, April 1, 2013
6 Problems and pitfalls regarding WHO-defined diagnosis of early/prefibrotic primary myelofibrosis versus essential thrombocythemia Leukemia, April 10, 2013 Review Article
7 Comparative Review of the Safety and Efficacy of Ferric Carboxymaltose Versus Standard Medical Care for the Treatment of Iron Deficiency Anemia in Bariatric and Gastric Surgery Patients Obesity Surgery, April 12, 2013 Review Article
8 Long-term safety and efficacy of sustained eculizumab treatment in patients with paroxysmal nocturnal haemoglobinuria British Journal of Haematology, April 26, 2013
9 Hematological and hemorheological determinants of resting and exercise-induced hemoglobin oxygen desaturation in children with sickle cell disease Haematologica, April 3, 2013 Free full text
10 Defective telomere elongation and hematopoiesis from telomerase-mutant aplastic anemia iPSCs The Journal of Clinical Investigation, April 25, 2013 Free full text
11 Genetic modifiers of sickle cell anemia in the BABY HUG cohort: Influence on laboratory and clinical phenotypes American Journal of Hematology, April 24, 2013
12 Successful treatment of non-Hodgkin lymphoma associated immune thrombocytopenia with involved field radiotherapy Hematological Oncology, April 24, 2013
13 Verifying Hellström-Lindberg score as predictive tool for response to erythropoietin therapy according to the International Working Group criteria, in anemic patients affected by myelodysplastic syndrome: a monocentric experience International Journal of Hematology, April 4, 2013 Review Article
14 Population PK/PD modeling of eltrombopag in subjects with advanced solid tumors with chemotherapy-induced thrombocytopenia Cancer Chemotherapy and Pharmacology, April 10, 2013
15 Sustained remissions of immune thrombocytopenia associated with the use of thrombopoietin receptor agonists Transfusion, March 11, 2013
16 High response rate and improved exercise capacity and quality of life with a new regimen of darbepoetin alfa with or without filgrastim in lower-risk myelodysplastic syndromes: a phase II study by the GFM Annals of Hematology, April 10, 2013 Review Article
17 Comparison of diagnostic performance of the heparin-induced thrombocytopenia expert probability and the 4Ts score in screening for heparin-induced thrombocytopenia Blood Coagulation & Fibrinolysis, April 10, 2013
18 Chemotherapy-induced anemia: the story of darbepoetin alfa Current Medical Research and Opinion, April 10, 2013 Review Article
19 Allogeneic Hematopoietic Cell Transplantation for Fanconi Anemia in Patients With Pretransplantation Cytogenetic Abnormalities, Myelodysplastic Syndrome, or Acute Leukemia Journal of Clinical Oncology, April 5, 2013
20 Prevalence of iron deficiency across different tumors and its association with poor performance status, disease status and anemia Annals of Oncology, April 15, 2013
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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