Looking for the latest in oncology clinical literature? You've found the right page. MDLinx Oncology medical editors comb through the top peer-reviewed clinical journals for the articles they think will make a difference to you and your practice. You'll find them organized here by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants and the whole cancer care team can stay current on the literature as it is published.
On this page, you'll also find MDLinx exclusive content, including monthly highlights from our physician editor, D. Scott Cunningham, MD, PhD. We feature clinical pearls as well, from The Smartest Oncologist to oncology topics in The Smartest Pediatrician daily quiz challenges.
Your Unread Messages in Oncology
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D Scott Cunningham MD, PhD
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121 Higher n3-fatty acid status is associated with lower risk of iron depletion among food insecure Canadian Inuit women Full Text BMC Public Health, April 4, 2013 Clinical Article
122 Verifying Hellström-Lindberg score as predictive tool for response to erythropoietin therapy according to the International Working Group criteria, in anemic patients affected by myelodysplastic syndrome: a monocentric experience International Journal of Hematology, April 4, 2013 Review Article
123 Association in Cis of the Mutations 20 (CT) in the 5 Untranslated Region and IVS-II-745 (CG) on the -Globin Gene Hemoglobin, April 4, 2013 Clinical Article
124 Identification of the First Mutation in a Bre Motif of the -Globin Gene and its Inheritance with two Other α-Globin Gene Mutations in a Lebanese Family Hemoglobin, April 4, 2013
125 Novel Mutations Responsible for α-Thalassemia in Iranian Families Hemoglobin, April 4, 2013 Clinical Article
126 A retrospective study to evaluate the time burden associated with outpatient red blood transfusions indicated for anemia due to concomitantly administered chemotherapy in cancer patients Supportive Care in Cancer, April 4, 2013 Clinical Article
127 Hematological and hemorheological determinants of resting and exercise-induced hemoglobin oxygen desaturation in children with sickle cell disease Full Text Haematologica, April 3, 2013 Clinical Article
128 FcRIIa proteolysis as a diagnostic biomarker for heparin-induced thrombocytopenia Journal of Thrombosis and Haemostasis, April 3, 2013 Clinical Article
129 Moxifloxacin is more effective than tosufloxacin in reducing chemotherapy-induced febrile neutropneia in patients with hematological malignancies Leukemia and Lymphoma, April 3, 2013 Clinical Article
130 Automated quantitation of fetomaternal hemorrhage by flow cytometry for HbF-containing fetal red blood cells using probability state modeling International Journal of Laboratory Hematology, April 3, 2013 Clinical Article
131 Management of Newly Diagnosed Symptomatic Multiple Myeloma: Updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) Consensus Guidelines 2013 Mayo Clinic Proceedings, April 2, 2013 Clinical Guideline
132 Safety and efficacy of CYT387, a JAK1 and JAK2 inhibitor, in myelofibrosisOpen Leukemia, April 2, 2013 Clinical Article
133 Risk of Topical Anesthetic–Induced Methemoglobinemia: A 10-Year Retrospective Case-Control Study JAMA Internal Medicine, April 2, 2013 Evidence Based Medicine Clinical Article
134 Interferon-γ mediates anemia but is dispensable for fulminant toll-like receptor 9-induced macrophage activation syndrome and hemophagocytosis Arthritis & Rheumatism, April 2, 2013 Review Article
135 Low Serum Lipocalin Levels in Patients With Iron Deficiency Anemia Journal of Pediatric Hematology/Oncology, April 1, 2013 Clinical Article
136 Intravenous ferric carboxymaltose versus standard medical care in the treatment of iron deficiency anemia in patients with chronic kidney disease: a randomized, active-controlled, multi-center study Nephrology Dialysis Transplantation, April 1, 2013 Clinical Article
137 Dynamics of Anemia in Relation to Parasitic Infections, Micronutrient Status, and Increasing Age in South-Central Cote dIvoire The Journal of Infectious Diseases, March 29, 2013 Clinical Article
138 A randomized phase I/II trial of HQK-1001, an oral fetal globin gene inducer, in β-thalassaemia intermedia and HbE/β-thalassaemia British Journal of Haematology, March 29, 2013 Clinical Article
139 Thrombotic risk in patients with immune thrombocytopenia and its association with antiphospholipid antibodies British Journal of Haematology, March 29, 2013 Clinical Article
140 Thrombin Generation in Children with Sickle Cell Disease: Relationship with Age, Hemolysis, Transcranial Doppler Velocity and Hydroxyurea Treatment European Journal of Haematology, March 29, 2013 Clinical Article
As reported in the Journal of Pathology, the expression of vascular endothelial growth factor receptor (VEGFR)-1 is elevated in invasive hepatocellular cancer (HCC) specimens. In a study based on 135 HCC specimens, elevated VEGFR-1 was also associated with worse recurrence-free and overall survival.
Read the article summaryAs reported in Cancer, researchers from the NCI have reported that patients with AIDS have a 4-fold increased risk of HCC compared to the general population. The study findings were based on 615,150 patients with AIDS between 1980 and 2009. The risk for HCC in patients with AIDS was essentially the same during the monotherapy/dual therapy and highly active anti-retroviral therapy eras.
Read the article summaryAs reported in the International Journal of Cancer Research and Treatment, the pre-operative level of RAB25 is a predictor of disease-free survival (HR=18.2) and overall survival (HR=33.6) in patients with ovarian cancer. The study involved 36 and 16 women with ovarian cancer and benign tumors, respectively. The pre-operative cell-free DNA of genes (B2M, RAB25, CLDN4, and ABCF2) were measured and RAB25 was shown to be an independent prognostic factor.
Read the article summary1 Management of Newly Diagnosed Symptomatic Multiple Myeloma: Updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) Consensus Guidelines 2013 Mayo Clinic Proceedings, April 2, 2013 Clinical Guideline
2 High-dose cyclophosphamide compared with antithymocyte globulin for treatment of acquired severe aplastic anemia Experimental Hematology, April 12, 2013
3 Cytoreduction plus low-dose aspirin versus cytoreduction alone as primary prophylaxis of thrombosis in patients with high-risk essential thrombocythaemia: an observational study British Journal of Haematology, April 15, 2013
4 Low Serum Lipocalin Levels in Patients With Iron Deficiency Anemia Journal of Pediatric Hematology/Oncology, April 1, 2013
5 Intravenous ferric carboxymaltose versus standard medical care in the treatment of iron deficiency anemia in patients with chronic kidney disease: a randomized, active-controlled, multi-center study Nephrology Dialysis Transplantation, April 1, 2013
6 Problems and pitfalls regarding WHO-defined diagnosis of early/prefibrotic primary myelofibrosis versus essential thrombocythemia Leukemia, April 10, 2013 Review Article
7 Comparative Review of the Safety and Efficacy of Ferric Carboxymaltose Versus Standard Medical Care for the Treatment of Iron Deficiency Anemia in Bariatric and Gastric Surgery Patients Obesity Surgery, April 12, 2013 Review Article
8 Long-term safety and efficacy of sustained eculizumab treatment in patients with paroxysmal nocturnal haemoglobinuria British Journal of Haematology, April 26, 2013
9 Hematological and hemorheological determinants of resting and exercise-induced hemoglobin oxygen desaturation in children with sickle cell disease Haematologica, April 3, 2013 Free full text
10 Defective telomere elongation and hematopoiesis from telomerase-mutant aplastic anemia iPSCs The Journal of Clinical Investigation, April 25, 2013 Free full text
11 Genetic modifiers of sickle cell anemia in the BABY HUG cohort: Influence on laboratory and clinical phenotypes American Journal of Hematology, April 24, 2013
12 Successful treatment of non-Hodgkin lymphoma associated immune thrombocytopenia with involved field radiotherapy Hematological Oncology, April 24, 2013
13 Verifying Hellström-Lindberg score as predictive tool for response to erythropoietin therapy according to the International Working Group criteria, in anemic patients affected by myelodysplastic syndrome: a monocentric experience International Journal of Hematology, April 4, 2013 Review Article
14 Population PK/PD modeling of eltrombopag in subjects with advanced solid tumors with chemotherapy-induced thrombocytopenia Cancer Chemotherapy and Pharmacology, April 10, 2013
15 Sustained remissions of immune thrombocytopenia associated with the use of thrombopoietin receptor agonists Transfusion, March 11, 2013
16 High response rate and improved exercise capacity and quality of life with a new regimen of darbepoetin alfa with or without filgrastim in lower-risk myelodysplastic syndromes: a phase II study by the GFM Annals of Hematology, April 10, 2013 Review Article
17 Comparison of diagnostic performance of the heparin-induced thrombocytopenia expert probability and the 4Ts score in screening for heparin-induced thrombocytopenia Blood Coagulation & Fibrinolysis, April 10, 2013
18 Chemotherapy-induced anemia: the story of darbepoetin alfa Current Medical Research and Opinion, April 10, 2013 Review Article
19 Allogeneic Hematopoietic Cell Transplantation for Fanconi Anemia in Patients With Pretransplantation Cytogenetic Abnormalities, Myelodysplastic Syndrome, or Acute Leukemia Journal of Clinical Oncology, April 5, 2013
20 Prevalence of iron deficiency across different tumors and its association with poor performance status, disease status and anemia Annals of Oncology, April 15, 2013
Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncology more
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