Oncology - Basic Science/Genetics News & Articles

1 PARP1 and DNA-PKcs synergize to suppress p53 mutation and telomere fusions during T-lineage lymphomagenesis Oncogene, May 23, 2012

2 The Expression of HMGA2 Varies Strongly among Colon Carcinomas Anticancer Research, May 22, 2012

3 In vitro analysis of ovarian cancer response to cisplatin, carboplatin, and paclitaxel identifies common pathways that are also associated with overall patient survival British Journal of Cancer, May 21, 2012

4 Driver mutations determine survival in smokers and never-smokers with stage IIIB/IV lung adenocarcinomas Cancer, May 21, 2012

5 MSH3 Protein Expression and Nodal Status in MLH1-Deficient Colorectal Cancers Clinical Cancer Research, May 18, 2012

6 Phase I study of RO4929097, a gamma secretase inhibitor of Notch signaling, in patients with refractory metastatic or locally advanced solid tumors Journal of Clinical Oncology, May 17, 2012

7 Inhibition of autophagy and tumor growth in colon cancer by miR-502 Oncogene, May 16, 2012

8 Heparanase and cyclooxygenase-2 gene and protein expressions during progression of oral epithelial dysplasia to carcinoma Annals of Diagnostic Pathology, May 14, 2012

9 Regulation of thrombomodulin expression in prostate cancer cells Cancer Letters, May 14, 2012

10 Carbonic anhydrase ix promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy Clinical Cancer Research, May 11, 2012

11 PPARγ agonists regulate the expression of stemness and differentiation genes in brain tumour stem cells British Journal of Cancer, May 11, 2012

12 Allelic Transcripts Dosage Effect in Morphologically Normal Ovarian Cells from Heterozygous Carriers of a BRCA1/2 French Canadian Founder Mutation Cancer Prevention Research, May 10, 2012

13 B-cell regulator of immunoglobulin heavy-chain transcription (Bright)/ARID3a is a direct target of the oncomir microRNA-125b in progenitor B-cells Leukemia, May 8, 2012

14 Down-regulation of KRAS-interacting miRNA-143 predicts poor prognosis but not response to EGFR-targeted agents in colorectal cancer British Journal of Cancer, May 8, 2012

15 Toll-like receptors gene polymorphisms may confer increased susceptibility to breast cancer development The Breast, May 7, 2012

16 E2F4 plays a key role in Burkitt lymphoma tumorigenesis Leukemia, May 3, 2012

17 MiR182 overexpression in tumorigenesis of high-grade ovarian papillary serous carcinoma The Journal of Pathology, May 3, 2012

18 A cross-sectional analysis of the association between diet and insulin-like growth factor (IGF)-I, IGF-II, IGF-binding protein (IGFBP)-2, and IGFBP-3 in men in the United Kingdom Cancer Causes and Control, May 3, 2012

19 Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer Full Text Breast Cancer Research, May 3, 2012

20 Activation of silenced tumor suppressor genes in prostate cancer cells by a novel energy restriction-mimetic agent The Prostate, April 30, 2012

Stereotactic ablative radiotherapy for stage I NSCLC: Recent advances and controversies Journal of Thoracic Disease, 08/05/2011

1 Cancer of unknown primary site The Lancet - Early Online Publication, March 16, 2012

2 HLA-G inhibition of NK-cell cytolytic function is uncoupled from tumor cell lipid raft reorganization European Journal of Immunology, April 19, 2012

3 Receptor Tyrosine Kinase Genes Amplified in Glioblastoma Exhibit a Mutual Exclusivity in Variable Proportions Reflective of Individual Tumor Heterogeneity Cancer Research, April 6, 2012

4 Variants of the MTHFR gene and susceptibility to acute lymphoblastic leukemia in children: A synthesis of genetic association studies Cancer Epidemiology, March 30, 2012

5 Proteomic analysis identifies differentially expressed proteins in AML1/ETO acute myeloid leukemia cells treated with DNMT inhibitors azacitidine and decitabine Leukemia Research, March 29, 2012

6 Plerixafor salvage is safe and effective in hard-to-mobilize patients undergoing chemotherapy and filgrastim-based peripheral blood progenitor cell mobilization Journal of Oncology, April 12, 2012

7 Circadian genes and breast cancer susceptibility in rotating shift workers International Journal of Cancer, April 13, 2012

8 Down-regulation of Cbl-b by bufalin results in up-regulation of DR4/DR5 and sensitization of TRAIL-induced apoptosis in breast cancer cells Journal of Cancer Research & Clinical Oncology, March 30, 2012

9 Correlations of TOP2A gene aberrations and expression of topoisomerase II protein and TOP2A mRNA expression in primary breast cancer Pathology International, April 2, 2012

10 USP22 nuclear expression is significantly associated with progression and unfavorable clinical outcome in human esophageal squamous cell carcinoma Journal of Cancer Research & Clinical Oncology, March 30, 2012

11 Changes in cardiac biomarkers during doxorubicin treatment of pediatric patients with high-risk acute lymphoblastic leukemia: Associations with long-term echocardiographic outcomes Journal of Clinical Oncology, March 1, 2012

12 Nuclear expression of Rac1 in cervical premalignant lesions and cervical cancer cells BMC Cancer, March 28, 2012    Free full text

13 Carbonic anhydrase IX up-regulation is associated with adverse clinicopathologic and biologic factors in neuroblastomas Human Pathology, March 30, 2012

14 Cellular apoptosis susceptibility (chromosome segregation 1-like, CSE1L) gene is a key regulator of apoptosis, migration and invasion in colorectal cancer The Journal of Pathology, March 30, 2012

15 A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy Pharmacogenetics and genomics, March 30, 2012

16 MiR-124 inhibits cell proliferation in gastric cancer through downregulation of SPHK1 The Journal of Pathology, March 30, 2012

17 Novel, gross chromosomal alterations involving PTEN cooperate with allelic loss in prostate cancer Modern Pathology, April 4, 2012