Oncology News Articles

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The latest Cancer and Oncology news articles published daily by MDLinx physician editors who comb through the top peer-reviewed clinical journals for the medical articles that will make a difference to you and your practice. Organized by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants can stay current on latest oncology topics, symptoms, treatments, risk factors in Cancer and Hematology.

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Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Trends in central nervous system tumor incidence relative to other common cancers in adults, adolescents, and children in the United States, 2000 to 2010 Cancer, August 28, 2014    Clinical Article

2 Final results of a phase II study of paclitaxel, bevacizumab, and gemcitabine as first-line therapy for patients with HER2-negative metastatic breast cancer Clinical and Translational Oncology, August 28, 2014    Clinical Article

3 EMMPRIN and ADAM12 in prostate cancer: Preliminary results of a prospective study Tumor Biology, August 28, 2014    Clinical Article

4 Dose selection, pharmacokinetics, and pharmacodynamics of BRAF inhibitor dabrafenib (GSK2118436) Clinical Cancer Research, August 28, 2014    Clinical Article

5 Prostate volume index and chronic inflammation of the prostate type IV with respect to the risk of prostate cancer Urologia Internationalis, August 28, 2014    Clinical Article

6 Outcome of laparoscopic versus open resection for rectal cancer in elderly patients Revised(June 15, 2014) Journal of Surgical Research, August 28, 2014    Clinical Article

7 An investigation of the support needs of men and partners throughout the prostate cancer journey Psycho-Oncology, August 28, 2014    Clinical Article

8 Coffee plus honey versus topical steroid in the treatment of chemotherapy-induced oral mucositis: A randomized controlled trial Full Text BMC Complementary and Alternative Medicine, August 28, 2014    Clinical Article

9 Breast conserving treatment for ductal carcinoma in situ in the elderly: Can Radiation Therapy be Avoided? Our experience International Journal of Surgery, August 28, 2014    Clinical Article

10 Racial differences in adipose tissue distribution and risk of aggressive prostate cancer among men undergoing radiation therapy Cancer Epidemiology, Biomarkers & Prevention, August 28, 2014    Clinical Article

11 Melphalan and dexamethasone with or without bortezomib in newly diagnosed AL amyloidosis: A matched case–control study on 174 patients Leukemia, August 28, 2014    Clinical Article

12 Hypercoagulability in celiac disease - An update Autoimmunity Reviews, August 28, 2014    Review Article

13 Determination of dabigatran, rivaroxaban and apixaban by UPLC-MS/MS and coagulation assays for therapy monitoring of novel direct oral anticoagulants Journal of Thrombosis and Haemostasis, August 28, 2014    Clinical Article

14 Molecular pathways: regulation and targeting of kinetochore-microtubule attachment in cancer Clinical Cancer Research, August 28, 2014    Review Article

15 Factor XIII stiffens fibrin clots by causing fiber compaction Journal of Thrombosis and Haemostasis, August 28, 2014    Clinical Article

16 The effect of corn trypsin inhibitor and inhibiting antibodies for FXIa and FXIIa on coagulation of plasma and whole blood Journal of Thrombosis and Haemostasis, August 28, 2014    Clinical Article

17 Stem cell therapy in autoimmune rheumatic diseases: a comprehensive review Clinical Reviews in Allergy and Immunology, August 28, 2014    Review Article

18 Characteristics and associations of high-mitotic-rate melanoma JAMA Dermatology, August 28, 2014    Clinical Article

19 Genomic and epigenomic co-evolution in follicular lymphomas Leukemia, August 28, 2014    Clinical Article

20 Discovery and development of the Polo-like kinase inhibitor volasertib in cancer therapy Leukemia, August 28, 2014    Review Article

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Clinical Pearls in Oncology

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Highlights in Oncology

Increased incidence of second primary cancers in patients with salivary gland tumors

As reported in JAMA—Otolaryngology-Head & Neck Surgery, patients with salivary gland tumors have an increased risk of second primary tumors and newly developed cancers. Specifically, the cumulative 2-, 5-, and 10-year rates for second primary cancers are 4.4%, 8.3%, and 12.4%, respectively. Similarly, the cumulative 2-, 5-, and 10-year rates for newly diagnosed cancers are 1.1%, 3.4%, and 10.5%, respectively.

VPAC1 overexpression associated with colon cancer aggression

As reported in Tumor Biology, VPAC1 expression is increased in poorly differentiated compared to well-differentiated colon cancer. VPAC1 expression is also increased in the blood vessels and macrophages adjacent to colon cancer tissues compared to healthy tissues. The overexpression of VPAC1 is related to EGFR overexpression.

Loss of PTEN expression portends poor prognosis in IPMNs of the pancreas

As reported in Clinical Cancer Research, loss of PTEN in intraductal papillary mucinous neoplasms (IPMNs) of the pancreas (n=36) is associated with invasiveness and poor survival.

Other Topics in Oncology

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