Oncology News Articles

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The latest Cancer and Oncology news articles published daily by MDLinx physician editors who comb through the top peer-reviewed clinical journals for the medical articles that will make a difference to you and your practice. Organized by topic including breast, hematologic, thoracic, gastrointestinal and genitourinary cancers. In a matter of minutes, oncologists, oncology nurses, physician assistants can stay current on latest symptoms, treatments, risk factors, and clinical trials in Cancer and Hematology.

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Ranked, sorted, and summarized by MDLinx editors from the latest literature
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1 Impact of the National Breast and Cervical Cancer Early Detection Program on cervical cancer mortality among uninsured low-income women in the U.S., 1991–2007 American Journal of Preventive Medicine, July 28, 2014    Clinical Article

2 SWOG0919: a Phase 2 study of idarubicin and cytarabine in combination with pravastatin for relapsed acute myeloid leukaemia British Journal of Haematology, July 28, 2014    Clinical Article

3 Decreased expression of cystathionine β-synthase promotes glioma tumorigenesis Molecular Cancer Research, July 28, 2014

4 Targeting survival and cell trafficking in multiple myeloma and Waldenstrom macroglobulinemia using pan-class I PI3K inhibitor, buparlisib American Journal of Hematology, July 28, 2014    Clinical Article

5 Relationship between primary colorectal tumour and location of colorectal liver metastases ANZ Journal of Surgery, July 28, 2014    Clinical Article

6 Do chronic myeloid leukemia patients with late “warning” responses benefit from “watch and wait” or switching therapy to a second generation tyrosine kinase inhibitor? American Journal of Hematology, July 28, 2014    Clinical Article

7 Long progression-free survival with first-line paclitaxel plus platinum is associated with improved response and progression-free survival with second-line docetaxel in advanced non-small-cell lung cancer Cancer Chemotherapy and Pharmacology, July 28, 2014    Clinical Article

8 Utility of radiotherapy for treatment of basal cell carcinoma: review British Journal of Dermatology, July 28, 2014    Clinical Article

9 Effects of a short messaging service–based skin cancer prevention campaign in adolescents American Journal of Preventive Medicine, July 28, 2014    Clinical Article

10 Red blood cells of sickle cell disease patients exhibit abnormally high abundance of N-methyl D-aspartate receptors mediating excessive calcium uptake British Journal of Haematology, July 28, 2014    Clinical Article

11 Loss of MIR15A and MIR16-1 at 13q14 is associated with increased TP53 mRNA, de-repression of BCL2 and adverse outcome in chronic lymphocytic leukaemia British Journal of Haematology, July 28, 2014    Clinical Article

12 The role of serum erythropoietin level and JAK2 V617F allele burden in the diagnosis of polycythaemia vera British Journal of Haematology, July 28, 2014    Clinical Article

13 The genetics of hemoglobin A2 regulation in sickle cell anemia American Journal of Hematology, July 28, 2014    Clinical Article

14 A Phase 1 dose escalation study of idarubicin combined with methotrexate, vindesine and prednisolone for untreated elderly patients with Primary Central Nervous System Lymphoma: The GOELAMS LCP 99 trial American Journal of Hematology, July 28, 2014    Clinical Article

15 Germ cell tumors in children and adolescents in Finland: trends over 1969–2008 Cancer Causes and Control, July 28, 2014    Clinical Article

16 Sedentary behavior is associated with colorectal adenoma recurrence in men Cancer Causes and Control, July 28, 2014    Clinical Article

17 Mortality from lymphohematopoietic neoplasms and other causes in a cohort of laminated plastic workers exposed to formaldehyde Cancer Causes and Control, July 28, 2014    Clinical Article

18 Human papillomavirus 16/18 E7 viral loads predict distant metastasis in oral cavity squamous cell carcinoma Journal of Clinical Virology, July 28, 2014    Clinical Article

19 Risk and outcomes of chemotherapy-induced diarrhea (CID) among patients with colorectal cancer receiving multi-cycle chemotherapy Cancer Chemotherapy and Pharmacology, July 28, 2014    Clinical Article

20 Liposomal anthracycline chemotherapy and the risk of second malignancies in patients with Kaposi's sarcoma (KS) Cancer Chemotherapy and Pharmacology, July 28, 2014    Clinical Article

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Clinical Pearls in Oncology

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Highlights in Oncology

VPAC1 overexpression associated with colon cancer aggression

As reported in Tumor Biology, VPAC1 expression is increased in poorly differentiated compared to well-differentiated colon cancer. VPAC1 expression is also increased in the blood vessels and macrophages adjacent to colon cancer tissues compared to healthy tissues. The overexpression of VPAC1 is related to EGFR overexpression.

CHD7 associated with survival in pancreatic ductal adenocarcinoma patients receiving gemcitabine

As reported in Cancer Research, low CHD7 expression is associated with increased RFS and OS in pancreatic ductal adenocarcinoma patients receiving gemcitabine. There was no association between CHD7 expression and RFS or OS in patients who were not treated with gemcitabine.

CTC count predicts survival in mBC

As reported in The Lancet Oncology, circulating tumor cell (CTC) quantification in patients (20 studies; n = 1944) with metastatic breast cancer (mBC) predicts progression-free survival (PFS) and overall survival (OS), especially when coupled with clinicopathologic data. A CTC count ≥ 5/7.5 mL at baseline is associated with decreased PFS (HR = 1.92) and OS (HR = 2.78). An elevated CTC count 3-5 weeks and 6-8 weeks after treatment commences is also associated with decreased PFS (HR = 1.85 and 2.20) and OS (HR = 2.26 and 2.91).


Other Topics in Oncology

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