Immunophenotypic heterogeneity of normal plasma cells: comparison with minimal residual plasma cell myeloma
Journal of Clinical Pathology, 08/21/2012
Liu D et al. – Non–neoplastic plasma cells in BM are more immunophenotypically heterogeneous than previously understood; however, these immunophenotypic variations differ from those of PCM. With advances in multicolour flow cytometry and application of recently validated markers, PCM MRD can still be reliably distinguished from non–neoplastic plasma cells.