Marked heterogeneity of ERG expression in large primary prostate cancers
Modern Pathology, 08/21/2012
Minner S et al. – Marked intrafocal heterogeneity challenges the concept of TMPRSS2–ERG fusion always representing an early step in prostate cancer development. Marked heterogeneity also compromises the concept of analyzing ERG status for treatment decisions in diagnostic needle core biopsies.