LRP1B Deletion in High-Grade Serous Ovarian Cancers Is Associated with Acquired Chemotherapy Resistance to Liposomal Doxorubicin
Cancer Research, 08/17/2012
Cowin PA et al. – The findings underscore the large degree of variation in DNA copy number in spatially and temporally separated tumors in High–grade serous cancer (HGSC) patients, and they define LRP1B as a potential contributor to the emergence of chemotherapy resistance in these patients.



