Tumor volume delineation in head and neck cancer with 18-fluor-fluorodeoxiglucose positron emission tomography: adaptive thresholding method applied to primary tumors and metastatic lymph nodes
Clinical and Translational Oncology, 08/08/2012
Perez–Romasanta LA et al. – The present study highlights the considerable challenges involved in using 18–fluor–fluorodeoxiglucose (18F–FDG) PET imaging for the delineation of GTV in head and neck neoplasms. The methods that rely mainly on SUVmax for thresholding, as the RS/B method, are very sensitive to partial volume effects and may provide unreliable results when applied on small lesions.