Global analysis of L1-transcriptomes identified IGFBP-2 as a target of ezrin and NF-κB signaling that promotes colon cancer progression
Oncogene, 08/08/2012
Ben–Shmuel A et al. – The authors found that IGFBP–2 and L1 can form a molecular complex suggesting that L1–mediated signaling by the L1–ezrin–NF–κB pathway, that induces IGFBP–2 expression, has an important role in colorectal cancer (CRC) progression.



