Assessment of the redox profile and oxidative DNA damage (8-OHdG) in squamous cell carcinoma of head and neck
Journal of Cancer Research and Therapeutics, 07/27/2012
Kumar A et al. – The present results demonstrate significant Redox imbalance in cancer patients suggesting their paramount importance in the development of SCCHN. The 8–OHdG could be the potential biomarker for evaluating risk of SCCHN. To develop new approaches of SCCHN prevention, there is a need of detailed study and better understanding of the molecular mechanisms underlying oxidative stress and DNA damage.