Immune Function in Newly Diagnosed Children With Malignancy
Journal of Pediatric Hematology/Oncology, 06/29/2012
Wiegering V et al. – The authors detected higher values of CD4+ T cells and consecutively shifted CD4+/CD8+ ratio in all patients compared with the control group. In patients with lymphoma, interleukin–2 was upregulated in all subpopulations. On the basis of these findings an altered immune function could be found in children with different malignancies at diagnosis.