An ex vivo co-culture model system to evaluate stroma-epithelial interactions in breast cancer
International Journal of Cancer, 06/15/2012
Salameh TS et al. – This novel co–culture system provides an ideal model to study epithelial–stromal interactions in the mammary gland. Understanding the relationship between adipose tissue, the most abundant and least studied component of the breast stroma, and tumor epithelial cells is critical to clarifying the influence of obesity on the development, progression and prognosis of breast cancer.