Methylation signature of lymph node metastases in breast cancer patients Full Text
BMC Cancer, 06/15/2012
Barekati Z et al. – The results of the present study showed methylation heterogeneity between primary tumors and metastatic lesion. The contribution of aberrant methylation alterations of BMP6, BRCA1 and P16 genes in lymph node metastasis might provide a further clue to establish useful biomarkers for screening metastasis, which might improve prognosis and therapeutic management of the breast cancer patients.