A randomized phase II study of pomegranate extract for men with rising PSA following initial therapy for localized prostate cancer
Prostate Cancer & Prostatic Diseases, 06/13/2012
Paller CJ et al. – Pomegranate extract treatment was associated with 6 month increases in PSA doubling time (PSADT) in both treatment arms without adverse effects. The significance of this on–study slowing of PSADT remains unclear, reinforcing the need for placebo–controlled studies in this patient population.