Effect of all-trans retinoic acid on the growth of two nasopharyngeal cancer cell lines and its treatment potential in combination with cisplatin
European Archives of Oto-Rhino-Laryngology, 06/13/2012
Hung SH et al. – Only a low concentration of all–trans retinoid acid (ATRA) was required to produce a synergistic effect when combined with cisplatin, indicating the potential usefulness of a combination therapy regimen. Therefore, the combination of ATRA and cisplatin is a viable treatment option for nasopharyngeal cancer (NPC) and should be further investigated.