Transfusion of cryopreserved human red blood cells into healthy humans is associated with rapid extravascular hemolysis without a proinflammatory cytokine response
Transfusion, 06/04/2012
Hult A et al. – Although a significant level of extravascular hemolysis already occurred at 2 hours after transfusion of cryopreserved red blood cells (RBCs) ), there were no signs of proinflammatory cytokine production up to 48 hours after transfusion.



