Effect of miR-34b Overexpression on the Radiosensitivity of Non-small Cell Lung Cancer Cell Lines
Anticancer Research, 05/21/2012
Balca–Silva J et al. – The findings suggest that there was a significant reduction in B–cell CLL/lymphoma 2 (BCL2) expression but no significant differences were observed in the apoptotic cell population or the cycle profile. No significant effect was recorded in the H1299 irradiated cells. In the p53 wild type, KRAS mutated NSCLC cells, the overexpression of miR–34b increases radiosensitivity at low doses of radiation.