The clinical determinants of malignant transformation in oral epithelial dysplasia
Oral Oncology , 05/15/2012
Ho MW et al. – Although a number of these clinical determinants have previously been associated with higher malignant transformation in oral epithelial dysplasia (OED), the high–risk nature of lesions in non–smokers is of particular note and requires a greater emphasis and recognition amongst clinicians dealing with OED. It suggests that those non–smokers with OED, have an inherited or acquired predisposition and should be treated more aggressively; these should form the focus for further investigation.