Contrasting effects of diclofenac and ibuprofen on active imatinib uptake into leukaemic cells
British Journal of Cancer, 04/30/2012
Wang J et al. – On the basis of the expected impact of these two drugs on OCT–1 activity (OA), ibuprofen should be avoided in combination with imatinib. Further studies are warranted regarding the potential benefit of diclofenac to improve OA in a clinical setting.