Upgrading and Downgrading of Prostate Cancer from Biopsy to Radical Prostatectomy: Incidence and Predictive Factors Using the Modified Gleason Grading System and Factoring in Tertiary Grades Full Text
European Urology, 05/02/2012
Epstein JI et al. – Almost 20% of radical prostatectomy (RP) cases have tertiary patterns. A needle biopsy can sample a tertiary higher Gleason pattern in the RP, which is then not recorded in the standard Gleason score reporting, resulting in an apparent overgrading on the needle biopsy.