Expression of the T-cell regulatory marker FOXP3 in primary cutaneous large B-cell lymphoma tumor cells
British Journal of Dermatology, 05/04/2012
Felcht M et al. – High numbers of Treg in the lymphoma microenvironment correlate with a better prognosis in Primary cutaneous B–cell lymphomas (PCBCL). In primary cutaneous diffuse large B–cell lymphoma, leg type (PCLBCL, LT) the presence of FOXP3+ tumor cells is beneficial for prognosis suggesting that FOXP3 expression of PCLBCL, LT tumor cells might serve as a tumor suppressor.