Large bowel obstruction due to colorectal carcinoma can be safely treated by colonic stent insertion - case series from a UK district general hospital
Colorectal Disease,  Clinical Article

Blake P et al. – The experience shows that stenting for obstructing colorectal cancer is a safe and effective method of alleviating acute and impending bowel obstruction and can be provided safely and effectively in a district general hospital.

Methods
  • Retrospective audit of all stent insertions in a single district general hospital between August 2003 and December 2009.
  • All patients had presented with acute bowel obstruction caused by malignant colorectal disease and details were collected prospectively and contemporaneously onto a database.
  • Stent insertion was a combined endoscopic and fluoroscopic procedure involving a colorectal surgeon and consultant radiologist.

Results
  • Stenting was attempted on 62 occasions in 54 patients.
  • The technical success rate was 86% and clinical success rate 84%.
  • The indications for stenting were for relief of acute bowel obstruction, palliation and as a bridge to surgery.
  • There were complications in fourteen cases (22.5%) including three perforations and one peri-operative mortality.
  • There were three cases of stent migration, six cases of re-stenosis and two stents became impacted with stool.
  • There were no incidents of acute or delayed haemorrhage in any patients.

Please login or register to follow this author.
Are you sure you want to Unfollow this Author?
► Click here to access PubMed, Publisher and related articles...
<< Previous Article | Next Article >>

Your Unread Messages in Oncology

See All >> Messages include industry-sponsored communications and special communications from MDLinx

Most Popular Oncology Articles

1 Long-term results of a randomised phase III trial of weekly versus three-weekly paclitaxel/platinum induction therapy followed by standard or extended three-weekly paclitaxel/platinum in European patients with advanced epithelial ovarian cancer European Journal of Cancer, August 6, 2014    Clinical Article

2 Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): survival outcomes of a randomised, open-label, multicentre, phase 3 trial and their association with pathological complete response The Lancet Oncology, August 19, 2014    Clinical Article

3 Prognosis of synchronous bilateral breast cancer: a review and meta-analysis of observational studies Breast Cancer Research and Treatment, August 1, 2014    Evidence Based Medicine    Review Article

4 Impact of trastuzumab treatment beyond disease progression for advanced/metastatic breast cancer on survival – Results from a prospective, observational study in Germany The Breast, July 24, 2014

5 Hsp27 regulates EGF/β-catenin mediated epithelial to mesenchymal transition in prostate cancer International Journal of Cancer, August 11, 2014    Clinical Article

6 A randomized, open-label, multicentre, phase 2/3 study to evaluate the safety and efficacy of lumiliximab in combination with fludarabine, cyclophosphamide and rituximab versus fludarabine, cyclophosphamide and rituximab alone in subjects with relapsed chronic lymphocytic leukaemia British Journal of Haematology, August 11, 2014    Clinical Article

7 Observation after a positive sentinel lymph node biopsy in patients with melanoma Annals of Surgical Oncology, August 20, 2014    Clinical Article

8 Vasectomy and risk of aggressive prostate cancer: a 24-year follow-up study Journal of Clinical Oncology, July 17, 2014

9 Real world costs and cost-effectiveness of rituximab for diffuse large B-cell lymphoma patients: A population-based analysis Full Text BMC Cancer, August 21, 2014    Free full text    Clinical Article

10 A phase 3 non-inferiority study of 5-FU/l-leucovorin/irinotecan (FOLFIRI) versus irinotecan/S-1 (IRIS) as second-line chemotherapy for metastatic colorectal cancer: updated results of the FIRIS study Journal of Cancer Research & Clinical Oncology, August 29, 2014    Clinical Article

11 Screening for prostate cancer in the US? Reduce the harms and keep the benefit International Journal of Cancer, August 15, 2014    Clinical Article

12 Phase II study of temozolomide (TMZ) and everolimus (RAD001) therapy for metastatic melanoma: A North Central Cancer Treatment Group study, N0675 American Journal of Clinical Oncology, August 14, 2014    Clinical Article

13 Prognostic relevance of peritumoral vascular invasion in immunohistochemically defined subtypes of node-positive breast cancer Breast Cancer Research and Treatment, August 4, 2014    Clinical Article

14 FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer (FIRE-3): a randomised, open-label, phase 3 trial The Lancet Oncology, August 4, 2014    Clinical Article

15 Calcium, vitamin D, dairy products, and mortality among colorectal cancer survivors: The Cancer Prevention Study-II Nutrition Cohort Journal of Clinical Oncology, July 9, 2014    Clinical Article

16 Rituximab versus a watch-and-wait approach in patients with advanced-stage, asymptomatic, non-bulky follicular lymphoma: an open-label randomised phase 3 trial The Lancet Oncology, March 7, 2014    Clinical Article

17 Survival outcome and reduction rate of Ki-67 between pre- and post-neoadjuvant chemotherapy in breast cancer patients with non-pCR Breast Cancer Research and Treatment, August 12, 2014    Clinical Article

18 Incidence of nonmelanoma skin cancer in relation to ambient UV radiation in white populations, 1978-2012 empirical relationships JAMA Dermatology, August 13, 2014    Review Article

19 Noninvasive radiofrequency treatment effect on mitochondria in pancreatic cancer cells Cancer, July 2, 2014    Clinical Article

20 Prognostic impact of MGMT promoter methylation and MGMT and CD133 expression in colorectal adenocarcinoma Full Text BMC Cancer, August 1, 2014    Free full text

Indexed Journals in Oncology: Journal of Clinical Oncology, Cancer Research, Annals Oncologymore

Register now to view all the MDLinx contents (FREE)!

  • Stay current on the latest literature, research and clinical news
  • Get special communications and offers from MDLinx and our sponsors
  • Receive invitations to paid market research
View Samples and Register

Connect with us, stay current.

Receive the latest mecial news
updates for free via email

Sign up!

Subscribe to our free RSS feeds:

Get the latest news in your specialty automatically added to your newsreader or your personal My Yahoo!, Google, My MSN or My AOL page. Learn More

Close