Role and Regulation of STAT3 Phosphorylation at Ser727 in Melanocytes and Melanoma Cells

Journal of Investigative Dermatology, 04/06/2012

The results indicate that signal transducer and activator of transcription 3 (STAT3) phosphorylation on STAT3 is not necessarily a secondary event after Tyr705 phosphorylation and suggest that it has a role in the regulation of cell survival activity and nuclear translocation of STAT3 in melanocytic cells.

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