Therapeutic effects of metformin in breast cancer: Involvement of the immune system?
Cancer Immunology, Immunotherapy, 06/22/2011
Schott S et al. – The biguanide class oral antidiabetic metformin has been shown capable of enhancing cell cycle arrest and inducing apoptosis as well as reducing growth factor signaling.Methods
- Several studies are underway to evaluate possible role of metformin in breast cancer treatment
- Authors discuss metformin’s anticancer effects including potential impact of immune system