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von Hippel–Lindau protein promotes Skp2 destabilization on DNA damage
Oncogene, 03/10/2011

Roe J–S et al. – These results identify the tumor suppressor function of pVHL in delaying the S–phase progression to inhibit cell proliferation on DNA damage. Clinically, this report explains as to why Skp2 accumulates abnormally in renal cell carcinoma tissues.

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